Anticardiolipin Antibodies in Patients with Behçet's Disease

Prevalence of antiphospholipid antibodies in Behçet's disease: A systematic review and meta-analysis

“…A total of 13 studies were considered as eligible, however, three studies were excluded due to unusable data format. Therefore, finally, based on the study objectives and inclusion/exclusion criteria, ten studies [22][23][24][33][34][35][36][37][38][39] (a total of 999 participants from 380 BD patients and 619 controls) were included in this meta-analysis (Fig 1) and full texts of all the included ten studies were retrieved.…”

“…The major characteristics of the included studies are presented in Table 1. All of the included case-control studies were journal articles and on adult subjects [22][23][24][33][34][35][36][37][38][39]. Among these ten studies, five were conducted on European populations across five different countries (Serbia [39], Turkey [23], Spain [37], the UK [35] and Israel [34]), while the remaining five studies were from Asia (Iran [24], Oman [36] and Korea [22,38]) and Africa (Egypt [33]).…”

“…All of the included case-control studies were journal articles and on adult subjects [22][23][24][33][34][35][36][37][38][39]. Among these ten studies, five were conducted on European populations across five different countries (Serbia [39], Turkey [23], Spain [37], the UK [35] and Israel [34]), while the remaining five studies were from Asia (Iran [24], Oman [36] and Korea [22,38]) and Africa (Egypt [33]). All of the ten studies assessed the prevalence of aCL [22][23][24][33][34][35][36][37][38][39], while anti-β2-GPI antibody was screened in one study [36] and LA in a single study [33].…”

“…The median score of NOS was 7. Therefore, among the ten studies, five were considered as of high methodological quality (low risk of bias) which scored �7 [23,33,[36][37][38], whereas, the other five studies [22,24,34,35,39] which scored <7 were therefore considered as of low methodological quality studies (high risk of bias).…”