Anticancer property of sediment actinomycetes against MCF–7 and MDA–MB–231 cell lines

Molecular analysis and anticancer properties of two identified isolates, Fusarium solani and Emericella nidulans isolated from Wady El–Natron soil in Egypt against Caco–2 (ATCC) cell line

“…Macroconidia were formed after [4][5][6][7] days from short multi-branched conidiophores which may form sporodochia. They are 3-septate, fusiform, cylindrical, often moderately curved, with an indistinctly pedicellate foot cell and a short blunt apical cell, (28)(29)(30)(31)(32)(33)(34)(35)(36)(37)(38)(39)(40)(41)(42) 毺m 暳 4-6 毺m).…”

“…Many of the developed antitumor drugs are derived from algal metabolites [4] and these metabolites play an important role in identification of new pharmaceutical compounds [5,6] . Also actinomycetes are one of the most important sources for new bioactive compounds such as antibiotics and enzymes [7,8] . The use of fungi for the production of commercial products is ancient, but it has increased rapidly over the last 50 years.…”

Statistical optimization and anticancer activity of a red pigment isolated from Streptomyces sp. PM4

“…It was found that 50 µg/mL of pigment could greatly inhibit the cell growth. The 20 ìg/mL [19] . Ravikumar et al [20] also reported the anticancer property of sediment actinomycetes against and MDA-MB-231 cell lines with the IC 50 value range from 10.13 to 18.54.…”

“…The 20 ìg/mL [19] . Ravikumar et al [20] also reported the anticancer property of sediment actinomycetes against and MDA-MB-231 cell lines with the IC 50 value range from 10.13 to 18.54. Thus the present study also indicating that the pigment is having potential cytotoxic activity against cancer cell lines.…”

Review on bioactive potential of marine microbes

“…nov. DVR D4 (Dasari et al, 2012). Actinomycetes from marine sediment have anticancer activity against breast cancer cell lines MCF-7 and MDA-MB-231 (Ravikumar et al, 2012). The cytotoxicity and antioxidant activity of 5-(2,4-dimethylbenzyl)pyrrolidin-2-one (DMBPO) extracted from marine Streptomyces VITSVK5 sp.…”