Anticancer profile of coumarin 6-based Ir(<scp>iii</scp>) photocatalysts under normoxia and hypoxia by ROS generation and NADH oxidation

Yadav, Ashish Kumar; Upadhyay, Aarti; Bera, Arpan; Kushwaha, Rajesh; Mandal, Arif Ali; Acharjee, Sagar; Kunwar, Amit; Banerjee, Samya

doi:10.1039/d4qi01601g

Inorg. Chem. Front.

2024

DOI: 10.1039/d4qi01601g

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Anticancer profile of coumarin 6-based Ir(iii) photocatalysts under normoxia and hypoxia by ROS generation and NADH oxidation

Ashish Kumar Yadav,

Aarti Upadhyay,

Arpan Bera

et al.

Abstract: Coumarin 6 appended Ir(iii) photocatalysts exhibited light activated anticancer effects against cancer cells via mitochondrial depolarization driven apoptosis by inducing type-I (NADH oxidation) and type-II (ROS generation) mechanisms.

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Anticancer profile of coumarin 6-based Ir(iii) photocatalysts under normoxia and hypoxia by ROS generation and NADH oxidation

Abstract: Coumarin 6 appended Ir(iii) photocatalysts exhibited light activated anticancer effects against cancer cells via mitochondrial depolarization driven apoptosis by inducing type-I (NADH oxidation) and type-II (ROS generation) mechanisms.

Cited by 0 publications

References 86 publications

No citations

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