Anticancer, anti-inflammatory and analgesic activities of aminoalcohol-based quinoxaline small molecules
Jannyely Moreira Neri,
Paula Emília Apolônio Siqueira,
Ana Luiza Cabral de Sá Leitão Oliveira
et al.
Abstract:Purpose:
Bioactive molecules are relevant to fight cancer and associated conditions. Quinoxaline is a privileged N-heterocycle, notably as anticancer agents. Herein, we report the evaluation of the quinoxaline derivatives DEQX and OAQX as anticancer agents, as well as in function of their anti-inflammatory and analgesic activities.
Methods:
Quinoxalines were synthesized and tested as anticancer agents based on cell viability and Annexin V-FITC apoptosis. Anti-inflammato… Show more
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