CompoundNormal human mammary Cell line
Concentrations
Critical findings ReferenceCapsaicin MCF-10A 10, 25, 50 and 100µM 90% of the cells survived after 72 h of treatment even with 100µM concentration compared to the IC 50 value of 56.3 µM achieved in transformed phenotype in H-ras MCF10A cells Kang et al, 2003 Alpha-santalol MCF-10A 10, 25, 50, 75 and 100µM Cell viability was affected only at 100 µM concentrations after 48 h treatment. 85% of cells were viable when compared to MCF-7 and MDA-MB231 breast cancer cells having significant cell death staring at 25 µM concentration. Santha et al, 2013 DATS MCF-10A 20 and 40µM Cell viability was unaffected at the indicated concentrations compared to cancerous cells (MCF-7, MDA-MB231). MCF-10A cells were more resistant to DATS-induced apoptosis Kumar et al, 2013