Antibody responses after two doses of SARS-CoV-2 mRNA-1273 vaccine in an individual with history of COVID-19 re-infection

Inada, Makoto; Ishikane, Masahiro; Terada, Mari; Matsunaga, Akira; Maeda, Kenji; Iwamoto, Noriko; Ujiie, Mugen; Kutsuna, Satoshi; Morioka, Shigefumi; Ishizaka, Yukihito; Mitsuya, Hiroaki; Ohmagari, Norio

doi:10.1016/j.ijid.2022.03.017

International Journal of Infectious Diseases

2022

DOI: 10.1016/j.ijid.2022.03.017

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Antibody responses after two doses of SARS-CoV-2 mRNA-1273 vaccine in an individual with history of COVID-19 re-infection

Makoto Inada

Masahiro Ishikane

Mari Terada

et al.

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2024

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Factors associated with SARS-CoV-2 vaccine hesitancy after stroke: a cross-sectional study

Hu,

Zhu,

Bai

et al. 2024

BMC Public Health

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Background The vaccination status of post-stroke patients, who are at high risk of severe outcomes from Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), is a significant concern, yet it remains unclear. We aimed to explore the vaccination status, factors associated with vaccine hesitancy, and adverse effects after vaccination among post-stroke patients. Methods This multi-center observational study enrolled hospitalized post-stroke patients from six Chinese hospitals (Oct 1, 2020 - Mar 31, 2021), examining vaccine uptake and self-reported reasons for vaccine hesitancy, utilizing logistic regression to investigate risk factors for vaccine hesitancy, and recording any adverse reactions post-vaccination. Results Of the total 710 post-stroke patients included in the study, 430 (60.6%) had completed the recommended full-3 dose SARS-CoV-2 vaccination, with 176 (24.8%) remaining unvaccinated. The most common reasons for vaccine hesitancy were concerns about vaccine side effects (41.5%) and impaired mobility (33.9%). Logistic regression identified advanced age (aOR = 1.97, 95%CI: 1.36–2.85, P = 0.001), lower Barthel Index score (aOR = 0.88, 95%CI: 0.82–0.93, P = 0.018), higher Modified Rankin Scale score (aOR = 1.85, 95%CI: 1.32–2.56, P = 0.004), and poorer usual activity level of EuroQol 5-Dimension (aOR = 2.82, 95%CI: 1.51–5.28, P = 0.001) as independent risk factors for vaccine hesitancy. Approximately 14.8% reported minor adverse reactions, mainly pain at the injection site. Conclusion We found that post-stroke patients have insufficient SARS-CoV-2 vaccination rates, with key risk factors for vaccine hesitancy including concerns about side effects, advanced age, and functional impairments. No severe adverse reactions were observed among the vaccinated population.

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Factors associated with SARS-CoV-2 vaccine hesitancy after stroke: a cross-sectional study

Hu,

Zhu,

Bai

et al. 2024

BMC Public Health

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Antibody responses after two doses of SARS-CoV-2 mRNA-1273 vaccine in an individual with history of COVID-19 re-infection

Cited by 1 publication

References 13 publications

Factors associated with SARS-CoV-2 vaccine hesitancy after stroke: a cross-sectional study

Factors associated with SARS-CoV-2 vaccine hesitancy after stroke: a cross-sectional study

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