Antibody mimetics: The next generation antibody engineering, a retrospective and prospective analysis
Siran Zhang,
Longjiang Wu,
Mei Dang
Abstract:Antibody mimetics represent the fourth generation of antibody engineering, following polyclonal antibodies, monoclonal antibodies, and genetically engineered antibody fragments. Despite cumulative studies highlighting the advantages of antibody mimetics, including enhanced recognition properties, superior affinity, stability, penetrability, and cost‐effectiveness, a comprehensive review of this evolving field is notably absent. In this study, spanning 1986–2023 and analyzing 24,318 publications, we undertake a… Show more
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