Antibody fluorescein-doped silica nanobioconjugates for the ultrasensitive detection of prostate-specific antigen

Abstract

Herein, we report the bioconjugation of anti-prostate-specific antigen polyclonal antibodies (pAb) onto the fluorescein-doped silica nanoparticles to detection of prostate-specific antigen (PSA). Fluorescein-isothiocyanate (FITC) was the fluorescent dye used and...