Antibody-containing cell response of sheep to intestinal infusion of killed Brucella abortus cells

Beh, K.J.

doi:10.1016/0008-8749(80)90190-2

Cited by 2 publications

(1 citation statement)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These immunocytes mostly have the appearance of mature plasma cells (CEBRA et al, 1977;HUSBAND, 1982 andGELDOF et al, 1984). The immunoglobulins secreted by these cells may pass across the basement membrane and epithelium and enter the gut lumen or pass into the collecting terminal of the intestinal lymphatics (BEH, 1980(BEH, , 1985KAWANASHI et al, 1983;HUSBAND & DUNKLEY, 1985).…”

Section: Introductionmentioning

confidence: 99%

Hymenolepis citelli, H. diminutaandH. microstoma: immunoglobulin-containing cells in the lamina propria of the mouse gut during primary and secondary infections

Alghali

1987

J. Helminthol.

View full text Add to dashboard Cite

The indirect immunofluorescent technique was used to determine the occurrence of IgA, IgM and IgG1 immunoglobulin-containing cells in local intestinal mucosal immune responses to Hymenolepis citelli, H. diminuta and H. microstoma infections in mice. In the intestinal lamina propria of H. citelli and H. diminuta infected mice there was no increase in the mean numbers of immunoglobulin-containing cells when compared with uninfected control mice, but there was in H. microstoma infected mice. The numbers of IgG1 – positive cells in both infected and uninfected mice were very small relative to IgA and IgM immunocytes. The distribution of immunocytes in the lamina propria of infected and uninfected mice was essentially similar and the localization of isotypes in duodenal sections showed no immunoglobulins in the villous epithelial cells. There was also no marked difference between primary and secondary infections indicating that immunoglobulin-containing cells play no major role in functional immunity against hymenolepid infections in the mouse. The presence of IgA and IgM was also demonstrated on the tegument of the tapeworms, although the distribution was patchy and more abundant on H. microstoma than on H. diminuta or H. citelli. The time of appearance of both isotypes was latest on H. citelli.

show abstract

Section: Introductionmentioning

confidence: 99%