Antibiotics for treating osteomyelitis in people with sickle cell disease

Martí‐Carvajal, Arturo J; Agreda-Pérez, Luis H; Cortés-Jofré, Marcela

doi:10.1002/14651858.cd007175

Cited by 10 publications

(12 citation statements)

References 22 publications

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“…A recent Cochrane review found no randomised trials on antibiotic approaches for osteomyelitis in people with sickle cell disease. 36 Over the past few decades the pattern of causative organisms has been changing, with more resistant strains emerging.…”

Section: Which Organisms Cause Acute Osteomyelitis?mentioning

confidence: 99%

Acute haematogenous osteomyelitis in children

Yeo

Ramachandran

2014

BMJ

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Section: Which Organisms Cause Acute Osteomyelitis?mentioning

confidence: 99%

Acute haematogenous osteomyelitis in children

Yeo

Ramachandran

2014

BMJ

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“…Of the 39 reviews that reported the use of a website, 34 reviews (87%) reported this in the Search methods for identification of studies section. The remaining 5 reviews reported searching websites in the Potential biases section . This was usually a statement that websites were searched for unpublished literature to counteract bias in the published literature.…”

Section: Resultsmentioning

confidence: 99%

A review of the reporting of web searching to identify studies for Cochrane systematic reviews

Briscoe

2017

Research Synthesis Methods

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The literature searches that are used to identify studies for inclusion in a systematic review should be comprehensively reported. This ensures that the literature searches are transparent and reproducible, which is important for assessing the strengths and weaknesses of a systematic review and re-running the literature searches when conducting an update review. Web searching using search engines and the websites of topically relevant organisations is sometimes used as a supplementary literature search method. Previous research has shown that the reporting of web searching in systematic reviews often lacks important details and is thus not transparent or reproducible. Useful details to report about web searching include the name of the search engine or website, the URL, the date searched, the search strategy, and the number of results. This study reviews the reporting of web searching to identify studies for Cochrane systematic reviews published in the 6-month period August 2016 to January 2017 (n = 423). Of these reviews, 61 reviews reported using web searching using a search engine or website as a literature search method. In the majority of reviews, the reporting of web searching was found to lack essential detail for ensuring transparency and reproducibility, such as the search terms. Recommendations are made on how to improve the reporting of web searching in Cochrane systematic reviews.

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“…In the absence of randomized controlled trials evidence is lacking about best practices. (Marti‐Carvajal & Agreda‐Perez, ) Targeted antibiotics should be started as soon as bone or articular infection is suspected. Incision and drainage should be undertaken in any case with abscess formation, or if a patient does not respond to initial therapy.…”

Section: Specific Infectionsmentioning

confidence: 99%

How we prevent and manage infection in sickle cell disease

et al. 2015

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Summary Sickle cell disease (SCD) affects approximately 100 000 people in the US, 12 500 in the UK, and millions worldwide. SCD is typified by painful vaso‐occlusive episodes, haemolytic anaemia and organ damage. A secondary complication is infection, which can be bacterial, fungal or viral. Universal newborn screening, routine use of penicillin prophylaxis, availability of conjugated vaccines against S. pneumoniae and comprehensive care programmes instituted during the past few decades in industrialized countries have dramatically reduced childhood mortality and improved life expectancy. Yet patients with SCD remain at increased risk of infection. Unfortunately, the treatment of most bacterial infections that are common in SCD is not based on the results of randomized controlled clinical trials. In their absence, treatment decisions are based on consensus guidelines, clinical experience or adapting treatment applied in other diseases. This leads to wide variation in treatment among institutions and even between treating physicians in a single institution. Prevention of infection, when possible, is most important and we focus on prevention through targeted prophylaxis and vaccination. We will share our management strategies for managing the more common infections in SCD and provide the rationale for our recommendations.

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Antibiotics for treating osteomyelitis in people with sickle cell disease

Cited by 10 publications

References 22 publications

Acute haematogenous osteomyelitis in children

Acute haematogenous osteomyelitis in children

A review of the reporting of web searching to identify studies for Cochrane systematic reviews

How we prevent and manage infection in sickle cell disease

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