Antibiotics for preventing infection at the surgical site: Single dose vs. multiple doses

Ahmed, Nehad J.; Haseeb, Abdul; AlQarni, Abdullmoin; AlGethamy, Manal; Mahrous, Ahmad J.; Alshehri, Ahmed M.; Alahmari, Abdullah K; Almarzoky Abuhussain, Safa S.; Mohammed Ashraf Bashawri, Ahmed; Khan, Amer H.

doi:10.1016/j.jsps.2023.101800

Search citation statements

Order By: Relevance

Paper Sections

Select...

Introduction1

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article2

Relationship

Self Cite0

Independent2

Authors

Journals

Cited by 2 publications

(1 citation statement)

References 93 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As a result of the extensive and inappropriate use of antibiotics the bacterial-resistant strains has become a key concern ( Mancuso et al, 2021 , Paulsamy et al, 2023 ). The effectiveness of antibiotics in killing bacteria has become increasingly limited ( Ahmed et al, 2023 ). In order to eliminate intracellular bacteria, higher concentrations of antibiotics are often required, potentially leading to side effects and toxicity ( Kamat and Kumari, 2023 , MubarakAli et al, 2015 , Radwan et al, 2023 ).…”

Section: Introductionmentioning

confidence: 99%

A significant antibiofilm and antimicrobial activity of chitosan-polyacrylic acid nanoparticles against pathogenic bacteria

AL-Fawares,

Alshweiat,

Al-Khresieh

et al. 2024

Saudi Pharmaceutical Journal

View full text Add to dashboard Cite

Section: Introductionmentioning

confidence: 99%

A significant antibiofilm and antimicrobial activity of chitosan-polyacrylic acid nanoparticles against pathogenic bacteria

AL-Fawares,

Alshweiat,

Al-Khresieh

et al. 2024

Saudi Pharmaceutical Journal

View full text Add to dashboard Cite

The pharmacological and clinical aspects of using gentamicin in cardiac surgery

Mohammed,

Saleh Alkaaby,

Alshawi

2024

PHAR

View full text Add to dashboard Cite

Surgical site infection (SSI) is a serious postoperative complication after cardiac surgery. The objective of this research is to examine the efficacy of administering gentamicin in minimizing the incidence of SSI while closely monitoring the therapeutic level of the drug. Prospective research included 50 Iraqi patients divided into two groups, 25 in each: Group 1 received a combination of flucloxacillin and ceftriaxone, while Group 2 received a combination of flucloxacillin and gentamicin 2 mg/kg of ideal body weight given before surgery, then 80 mg*3 for 48 hours after surgery. A total of five patients had an infection at the surgical site, with four patients in Group 1 and one patient in Group 2. Additionally, two patients in each group exhibited increased renal indices. Among the patients in Group 2, the highest concentration of gentamicin in the blood was ≤ 2.5 µg/ml for eight patients, while for 17 patients, the gentamicin concentration in the blood ranged from 3 to 4.4 µg/ml.

show abstract

Antibiotics for preventing infection at the surgical site: Single dose vs. multiple doses

Cited by 2 publications

References 93 publications

A significant antibiofilm and antimicrobial activity of chitosan-polyacrylic acid nanoparticles against pathogenic bacteria

A significant antibiofilm and antimicrobial activity of chitosan-polyacrylic acid nanoparticles against pathogenic bacteria

The pharmacological and clinical aspects of using gentamicin in cardiac surgery

Contact Info

Product

Resources

About