2014
DOI: 10.1002/14651858.cd001807.pub2
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Antibiotics for prelabour rupture of membranes at or near term

Abstract: Analysis 2.3. Comparison 2 Any antibiotic compared with placebo or no antibiotic (subgrouped by timing of induction of labour), Outcome 3 Maternal infectious morbidity (chorioamnionitis and/or endometritis).. .. .. .. Analysis 2.4. Comparison 2 Any antibiotic compared with placebo or no antibiotic (subgrouped by timing of induction of labour), Outcome 4 Stillbirth.

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Cited by 49 publications
(38 citation statements)
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“…A meta-analysis of 5 RCTs including 2699 women who were randomized to antibiotic group vs control group shows that antibiotic prophylaxis for term or near-term PROM is not associated with maternal or neonatal benefits. However, subgroup analysis of women with latency longer than 12 hours shows that women who received prophylactic antibiotics experience lower rates of chorioamnionitis and endometritis (risk ratio (RR) = 0.49, 95% CI = 0.27-0.91) and 0.12 (95% CI = 0.02-0.62), respectively [56]. Nevertheless, data from a local RCT conducted in Egypt in 2014 did not show statistical differences in the incidence of maternal infection or neonatal sepsis when prophylactic antibiotics were administered at or beyond 36 weeks of gestation [57].…”
Section: At 37 Weeks Of Gestation or Beyondmentioning
confidence: 99%
“…A meta-analysis of 5 RCTs including 2699 women who were randomized to antibiotic group vs control group shows that antibiotic prophylaxis for term or near-term PROM is not associated with maternal or neonatal benefits. However, subgroup analysis of women with latency longer than 12 hours shows that women who received prophylactic antibiotics experience lower rates of chorioamnionitis and endometritis (risk ratio (RR) = 0.49, 95% CI = 0.27-0.91) and 0.12 (95% CI = 0.02-0.62), respectively [56]. Nevertheless, data from a local RCT conducted in Egypt in 2014 did not show statistical differences in the incidence of maternal infection or neonatal sepsis when prophylactic antibiotics were administered at or beyond 36 weeks of gestation [57].…”
Section: At 37 Weeks Of Gestation or Beyondmentioning
confidence: 99%
“…15,16 The complication risk of PROM is increased if the mother has previous PROM, low body mass index, concomitant infection of the gestational tissues, and longer the time elapsed between the rupture and delivery. 17 PROM has essential significance for the further fate of pregnancy. Late diagnosis means wasted opportunity of appropriate intervention.…”
Section: B a C K G R O U N Dmentioning
confidence: 99%
“…Кохрановский метаанализ 2014 г. не выявил существенных различий между группами пациенток, получавшими и не получавшими антибиотики в связи с преждевременным излитием околоплодных вод при родах в срок или близких к сроку [23]. Отсутствие антибиотикопрофилактики не увеличивало риск развития хориоамнионита, эндометрита или раневой инфекции у матери, не повышало частоту раннего неонатального сепсиса [23].…”
Section: рекомендуется введение антибиотика в родах пациенткам-носитеunclassified