Antibiotics for mastitis in breastfeeding women

Jahanfar, Shayesteh; Ng, Christina; Teng, Cheong Lieng

doi:10.1002/14651858.cd005458.pub2

Cited by 47 publications

(48 citation statements)

References 25 publications

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“…The incidence of acute mastitis could be as high as 33% in the breastfeeding women . Presumably bacteria can get into the mammary tissue through cracked skin, and cause acute inflammation and abscess formation .…”

Section: Discussionmentioning

confidence: 99%

“…Histologic evaluation is required when the clinical picture is confusing. Antibiotics are commonly used, although its efficacy needs further study . Percutaneous drainage with urokinase irrigation can be used for large abscesses .…”

Section: Discussionmentioning

confidence: 99%

“…Mastitis is a benign inflammatory process of the breast with heterogeneous histopathological findings. The most common type of mastitis is the acute mastitis caused by bacterial infections in breastfeeding women . In surgical pathology practice, acute mastitis is less challenging than other types of mastitis.…”

mentioning

confidence: 99%

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Mastitis, a Radiographic, Clinical, and Histopathologic Review

et al. 2015

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Mastitis is a benign inflammatory process of the breast with heterogeneous histopathological findings, which clinically and radiographically may mimic a mammary carcinoma. We undertook a retrospective study on 37 cases of mastitis in our institution to correlate the radiographic imaging features and the clinical presentation with the histopathological findings. Histologically, there were 21 granulomatous, 7 fibrous, 3 plasma cell, 3 lupus, 2 lymphocytic, and 1 case of acute mastitis. Radiographically, 16/25 (64%) patients with ultrasound studies showed irregular hypoechoic masses suspicious for malignancy. Clinically, 38% of patients had an associated systemic disease.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Mastitis, a Radiographic, Clinical, and Histopathologic Review

et al. 2015

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“…Demographic variables and treatment details were analyzed using ANOVA and Pearson's Chi-square test. Ten women with lactational phlegmon (19.2%), 15 women with abscess (28.8%), and 27 women with UM (51.9%) were identified.…”

Section: Introductionmentioning

confidence: 99%

Lactational phlegmon: A distinct clinical entity affecting breastfeeding women within the mastitis‐abscess spectrum

Johnson

Mitchell

2019

Breast J

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We aimed to describe the presentation and treatment of lactational phlegmon, a unique complication of mastitis in breastfeeding women that may require surgical management. We retrospectively analyzed medical charts of breastfeeding women treated by a single breast surgeon for lactational phlegmon or the related conditions of abscess or uncomplicated mastitis (UM) from July 2016 to October 2018. Demographic variables and treatment details were analyzed using ANOVA and Pearson's Chi‐square test. Ten women with lactational phlegmon (19.2%), 15 women with abscess (28.8%), and 27 women with UM (51.9%) were identified. Phlegmon presented as a tender, erythematous, and nonfluctuant mass in a ductal distribution. Ultrasonography demonstrated an ill‐defined, complex fluid collection. Epidemiologically, women with phlegmon were similar to patients with abscess and UM. Women with phlegmon reported more intense deep breast massage than patients in the other two groups, but significantly lower rates of breast pump use than women with abscess (30.0% vs 80.0%, P < .05). Relative to women with UM, patients with complicated mastitis (CM, defined as phlegmon or abscess) reported greater utilization of nipple shields (36.0% vs 11.1%, P < .05). Treatment of phlegmon entailed effective milk removal, antibiotics (range 10‐30 days), and close follow‐up until both clinical and radiographic resolution (range 8 days to >3 months), with biopsy of persistent masses. Antibiotic duration was significantly longer for patients with phlegmon compared to those with UM (mean 15.0 days vs 9.7 days, P < .05). Two phlegmons coalesced into abscesses within 1 week of diagnosis. Lactational phlegmon is a complication of mastitis in breastfeeding women that is distinct from abscess and UM. Optimal treatment consists of an extended course of antibiotics and close follow‐up to monitor for coalescence into a drainable fluid collection and/or persistence of mass requiring biopsy.

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“…These findings reappear in the current WHO recommendations 2 . Major reasons mentioned for early weaning within this suggested time period are inflammatory reactions of the breast (milk stasis, mastitis) 3–7 . When symptoms of inflammatory breast disease appear, even the earliest interventions in clinical practice as breast feeding counselling or local application of ointments cannot provide the necessary conditions to continue breast feeding and take advantage of the associated long‐term health benefits 8 …”

Section: Introductionmentioning

confidence: 99%