Antibiotics Are Associated With Lower Relapse Rates in Outpatients With Acute Exacerbations of COPD

Adams, Sandra G.; Melo, J C; Luther, M; Anzueto, Antonio

doi:10.1378/chest.117.5.1345

Cited by 201 publications

(125 citation statements)

References 38 publications

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“…These results are further supported by Adams and colleagues [64] whose findings suggest that individuals treated with antibiotics had significantly lower relapse rates than those who did not receive antibiotics.…”

Section: Medications and Vaccinationssupporting

confidence: 72%

“…A number of researchers have linked AECOPD to bacterial infection by pathogens such as Streptococcus pneumoniae, Haemophilus influenzae, Pseudomonas aeruginosa and M. catarrhalis, these bacteria may be associated with increased sputum volume and purulence [59][60][61][62][63] . Antibiotics are often prescribed to alleviate and treat the cough and increased purulent sputum production that leads to increased breathlessness, and in these instances, the use of antibiotics is controversial [59,62,[64][65][66] . More recently, it has been suggested that there is an increased recognition that exacerbations may be due to viral infections of the upper respiratory tract so antibiotic treatment may not always be warranted.…”

Section: Medications and Vaccinationsmentioning

confidence: 99%

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Best practice in nursing care of dyspnea: The 6th vital sign in individuals with COPD

Bailey

Boyles

Cloutier

et al. 2013

JNEP

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Aim: The aim of this paper is to highlight evidence and key nursing practice, education, organization and policy recommendations from the original and revised Registered Nurses' Association of Ontario Best Practice Guideline, Nursing Care of Dyspnea: The 6th Vital Sign in Individuals with Chronic Obstructive Pulmonary Disease (COPD). This paper introduces the notion of dyspnea as the sixth vital sign and presents evidence from the RNAO Best Practice Guideline and other relevant literature to support and enhance nursing care of dyspnea in clients with COPD.Background: COPD is an increasingly serious health issue. Nurses have significant opportunity to positively influence client outcomes and quality of life by assessing dyspnea, identifying problems, and applying appropriate evidence-based interventions. Best practice guidelines developed by the RNAO provide a framework to enhance nursing practice and client care.Design: A panel of nurses was assembled for the initial development of the guideline and more recently, the revision to the original guideline.Method: A structured evidence review based on the scope of the original guideline and supported by three clinical questions was conducted to capture the relevant literature and guidelines published since the original publication.Results: As a result of this work recommendations for nursing practice and education are discussed. Organizational and policy recommendations are also outlined. Conclusions:Nurses have opportunity to positively influence client outcomes and quality of life by assessing dyspnea, identifying problems, and applying appropriate evidence-based interventions.Relevance to Clinical Practice: Recommendations made in the best practice guideline will enhance nursing care of dyspnea in clients with COPD and dyspnea should be recognized as the sixth vital sign in individuals with COPD.

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Section: Medications and Vaccinationssupporting

confidence: 72%

Section: Medications and Vaccinationsmentioning

confidence: 99%

Best practice in nursing care of dyspnea: The 6th vital sign in individuals with COPD

Bailey

Boyles

Cloutier

et al. 2013

JNEP

View full text Add to dashboard Cite

show abstract

“…Result of this study showed that combination of Augmentin (amoxicillin/clavulanate acid) and azithromycin is the most frequently initial antibiotic administered in ED for AECOPD. Even though the administration of initial antibiotic in ED serves as empirical treatment, the efficacy of antibiotic therapy in AECOPD is still controversial and has been the focus of an extensive review [8].…”

Section: Medication Profile Evaluationmentioning

confidence: 99%

Profile Assessment for Hospital Readmissionamong Male Patients of Acute Exacerbationchronic Obstructive Pulmonary Diseaseat Selected Hospital in Malaysia

Dzakwan

Hariadha

2017

Asian J Pharm Clin Res

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Background: Acute exacerbation chronic obstructive pulmonary disease (AECOPD) is a common lung disease characterized by airflow limitation that is not fully reversible and is both chronic and progressive. AECOPD is a sudden worsening of COPD symptoms that typically lasts for several days. AECOPD readmission has been one of global concern and was the fifth leading cause of disease burden in Malaysia, both clinically and economically.

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“…Antibiotics also decrease the relapse rates of exacerbationsin outpatients (Adams et al 2000). Therefore, antibiotherapy is strongly indicated expecially if the patient has purulant sputum and increase in dyspnea.…”

mentioning

confidence: 99%

Management of Acute Exacerbations

Kıraklı¹

2012

Chronic Obstructive Pulmonary Disease - Current Concepts and Practice

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Antibiotics Are Associated With Lower Relapse Rates in Outpatients With Acute Exacerbations of COPD

Cited by 201 publications

References 38 publications

Best practice in nursing care of dyspnea: The 6th vital sign in individuals with COPD

Best practice in nursing care of dyspnea: The 6th vital sign in individuals with COPD

Profile Assessment for Hospital Readmissionamong Male Patients of Acute Exacerbationchronic Obstructive Pulmonary Diseaseat Selected Hospital in Malaysia

Management of Acute Exacerbations

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