Antibiotic usage pattern among inpatients of a paediatric ward in a tertiary care hospital in Eastern India

Mukherjee, Shatavisa; Sen, Sukanta; Era, Nikhil; Biswas, Arunava; Datta, Kasturi; Tripathi, Santanu Kumar

doi:10.18203/2320-6012.ijrms20151422

Cited by 6 publications

(10 citation statements)

References 5 publications

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“…In this study, it was found that age, White Blood Cell (WBC) count status and system of illness were significantly associated with the use of antibiotics as shown in Table 3. Similar to these findings, studies that were done in India and Nigeria also found that these factors are associated with the use of antibiotics [18,36]. The age of paediatric patients was a factor that could influence the use of antibiotics.…”

Section: Discussionsupporting

confidence: 76%

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Antibiotic Prescribing Patterns in Paediatric Patients at Levy Mwanawasa University Teaching Hospital in Lusaka, Zambia

Mudenda¹

2020

Int J Pharm Pharmacol

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The use of antimicrobial agents has become a routine practice for the treatment of paediatric illnesses. The uncontrolled use of antibiotics has caused a rise in antimicrobial resistance. This study aimed to assess the antibiotic prescribing patterns in paediatric patients at Levy Mwanawasa University Teaching Hospital in Lusaka, Zambia. This was a cross-sectional study conducted between April 2019 to July 2019. The study population included both in-patients and outpatients aged between one month and eighteen years whose medical files were reviewed. A sample size of 357 medical files was conveniently sampled. Statistical Package for Social Sciences version 21.0 was used for data analysis. A chi-square test was used to assess the association between categorical variables. A p<0.05 was considered to be statistically significant at 95% confidence level. The majority of the medical files 230 (64.4%) were for paediatrics in the age group of 1 month to 5 years. Antibiotic prescribing was found to be 78.7%. The study revealed that 119 (33.3%) of patients required antibiotics and were on antibiotic treatment while 46 (12.9%) did not require antibiotics but were on antibiotic treatment. The most common diseases 147 (41.2%) were those affecting the respiratory system. The most commonly prescribed antibiotics were penicillins 154 (54.8%), followed by cephalosporins 88 (31.3%). The association between age, white blood cell count status, and system of illness with antibiotic use were statistically significant (χ 2 =15.083, p=0.001; χ 2 = 6.571, p=0.037 and χ 2 =27.717, p<0.0001). The study also found that the frequency of antibiotic use was high among paediatric patients as per the World Health Organization's prescribing indicators. The most commonly prescribed antibiotics to paediatric patients were penicillins.

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Section: Discussionsupporting

confidence: 76%

“…Excessive and inappropriate use of antibiotics has been a major contributor to the emerging problem of antibiotic resistance [17]. Paediatric patients are largely prone to be a victim of irrational antibiotic usage practice [18].…”

Section: Discussionmentioning

confidence: 99%

Antibiotic Prescribing Patterns in Paediatric Patients at Levy Mwanawasa University Teaching Hospital in Lusaka, Zambia

Mudenda¹

2020

Int J Pharm Pharmacol

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“…Moreover, a habit of recording adverse drug reaction must be also encouraged at all level of health care institution. 10 When treating infections, healthcare providers realize the importance of initiating antibiotic therapy as soon as possible. It is also recognized that tailoring pharmacologic therapy to the organism(s) responsible for the infection is equally important.…”

Section: Discussionmentioning

confidence: 99%

“…Obtaining appropriate cultures before initiating antimicrobial therapy plays an important role in patient care. 10 The foremost challenges in prescription of antibiotics are thus to achieve a rational choice and appropriate use of antibiotics and to recognize their potential problems. Physicians must also keep a clear understanding of need for microbiological diagnosis, use of antibiotics and make good judgment in clinical situations.…”

Section: Discussionmentioning

confidence: 99%

Prescription pattern of antibiotics in respiratory disorders in a tertiary care teaching hospital in Eastern part of India

Gupta

Chatterjee

2017

Int J Res Med Sci

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Background: Respiratory infections are increasing globally with parallel increase in world population, pollution, urbanization, overcrowding, global warming and poverty. Multi drug resistant virulent bacteria are growing very rapidly. The objective of this study was to know the prescribing pattern of antibiotics in hospitalized patients suffering from different common respiratory disorders.Methods: This was a retrospective and observational study. Data was captured from 1st January 2016 to 31st December 2016 at ICARE Institute of Medical Sciences and Research and Dr. B.C.Roy Hospital. Total 200 patients were taken for the study of age range from 10 to 50 years.Results: COPD, bronchial asthma, pneumonia and ARIs were the most frequent respiratory illnesses among patients attended Medicine OPD. Most common antibiotics prescribed were co-amoxyclav, ceftriaxone, moxifloxacin, clarithromycin, azithromycin and aminoglycosides.Conclusions: Injudicious use of antibiotics in trivial viral respiratory infections may give rise to antibiotic resistant strains in the community.

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“…[1] The rising incidence of bacterial resistance to most commonly used antibiotics, especially multi-drug resistant pneumococci, has mandated the judicious use of antibiotics in pediatric practice. [13] Most of the antibiotics are prescribed unnecessarily for viral infections like common cold. Appropriate drug utilization studies have been found to be effective in evaluating whether the drugs are utilized properly in medical, social, and economic aspects.…”

Section: Introductionmentioning

confidence: 99%

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Prabahar

2017

AJP

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Introduction: Children have high rates of minor infection, and because of their increased susceptibility to serious bacterial infection, they are frequently prescribed with antibiotics. The main aim of the study was to evaluate the antibiotics utilization pattern and check the adherence to the antibiotic policy in pediatric patients of a tertiary care teaching hospital. Materials and Methods: This prospective observational study was conducted for a period of 6 months in the inpatient Department of Pediatrics of a tertiary care teaching hospital after getting approval from the Research and Ethics Committee. 90 children from 1 month to 18 years age of either sex admitted to pediatric ward prescribed with antibiotics were included for the study, after getting informed consent from their parents. The lab data were noted down on follow-up. The patient charts were followed up throughout the period of hospitalization for drug interactions. The antibiotic utilization pattern was studied from the revised antibiotic prescribing policy of the Department of Pediatrics. The drug interactions were found using drugs.com. Results: Cephalosporins was the common class of antibiotics prescribed and majority of antibiotics were prescribed for a period of 1-5 days.

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Antibiotic usage pattern among inpatients of a paediatric ward in a tertiary care hospital in Eastern India

Cited by 6 publications

References 5 publications

Antibiotic Prescribing Patterns in Paediatric Patients at Levy Mwanawasa University Teaching Hospital in Lusaka, Zambia

Antibiotic Prescribing Patterns in Paediatric Patients at Levy Mwanawasa University Teaching Hospital in Lusaka, Zambia

Prescription pattern of antibiotics in respiratory disorders in a tertiary care teaching hospital in Eastern part of India

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