Antibiotic Resistance: The Silent Pandemia (in the COVID-19 Era)

Salgado-Peralvo, Ángel-Orión; Kewalramani, Naresh; Mateos-Moreno, María-Victoria

doi:10.1016/j.identj.2023.01.003

Cited by 1 publication

(1 citation statement)

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“…It should also be considered that when ATB are prescribed for preventive purposes, they should be administered preoperatively (at least 1 h before surgery) to achieve an adequate blood concentration, sufficient to exceed the minimum inhibitory concentration by 2 to 4 times. Exceeding this therapeutic range creates a window of selection for therapeutic overdose known as the "mutant selection window", which modifies the susceptibility of bacteria to ATB, making them resistant ( 34 ). The non-prescription of PAT could also not be considered a wrong approach in healthy, young, non-smoking patients, and in the presence of certain techniques such as, possibly, guided surgery which allows the placement of DIs in a minimally invasive way without elevating mucoperiosteal flaps ( 35 ).…”

Section: Discussionmentioning

confidence: 99%

Antibiotic prescribing patterns in the placement of dental implants in Europe: A systematic review of survey-based studies

Salgado-Peralvo,

Kewalramani,

Pérez-Jardón

et al. 2024

Med Oral

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Background The present systematic review aims to investigate the guidelines for prescribing Preventive Antibiotic Therapy (PAT) in the placement of dental implants (DIs) without anatomical constraints in healthy patients by clinicians in Europe and to compare them with current recommendations. Material and Methods A search was performed in 4 databases: Medline (via PubMed), Web of Science, Scopus, and LILACS. The criteria employed were those described in the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) declaration (PROSPERO Registration number: CRD42022382278). Results The electronic search identified 10 studies published between 2010 and 2023 that met the established criteria. Overall, 60.8% ± 24.1% of European professionals routinely prescribe PAT, with the most frequent regimen being perioperative (mean= 46.7% ± 24.3%), followed by postoperative PAT only (mean= 20.3% ± 9.7%). Conclusions The most commonly prescribed antibiotic both pre- and postoperatively is amoxicillin and, in allergic patients, clindamycin. In Europe, more doses of PAT are being prescribed than suggested by current recommendations. For this reason, more PAT education is needed in educational curricula to promote a more rational use of antibiotics to reduce the occurrence of antimicrobial resistance. Key words: Antimicrobial stewardship, surveys and questionnaires, antibiotic prophylaxis, dental implants, dental implantation, dental implantation, endosseous, surgical wound infection.

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Section: Discussionmentioning

confidence: 99%