Antibiotic Resistance Pattern of Urinary Isolates in a Tertiary Care Hospital in Berhampore, West Bengal

Bose, Mohua; Basu, Ranjan

doi:10.14260/jemds/2018/781

Cited by 1 publication

(1 citation statement)

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“…In this study, UTI was reported from 58.9% females and 48.1% males, which was similar to the findings by Bose et al, who reported UTI from 65.82% females and 34.18% males. 9 Female preponderance reported from various studies which were similar to this study: (58.28%) were female and (41.72%) were male by Rajabnia et al, (62.42%) females and (37.67%) males by Gupta et al, 65.82% females and 34.18% males by Bose et al [9][10][11] Most common organism isolated in this study were gramnegative bacteria like E. coli with 52.4% followed by Klebsiella with 26%, 20 (7.9%) each of Citrobacter and pseudomonas aeruginosa, Acinetobacter 8 (2.83%), Staph aureus 6 (2.12%), Proteus 4 (1.41%), Enterococcus 2 (0.7%), mixed organism 2 (0.7%). The percentage of bacterial species isolated in other studies also showed similar results (Hooton et al, 1996;García-Morúa et al, 2009).…”

Section: Discussionmentioning

confidence: 99%

Antibiotic resistance pattern in patients with urinary tract infection: an observational study

Mallam

Kiran

2019

Int J Basic Clin Pharmacol

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Background: Urinary tract infection (UTI) is one of the most common diseases caused by bacteria in communities and hospital settings. With the irrational prescription of antibiotics and their misuse leads to constant increase in resistance. This study aims to evaluate the spectrum and antibiotic resistance pattern of uropathogens and to provide a basis for appropriate antimicrobial therapy in patients with UTI.Methods: A retrospective observational study was carried out for a period of 6 months from April 2018 to September 2018 at general hospital Kakinada. Data of 282 positive urine culture reports and their antibiotic susceptibility test results were collected from the records of the Microbiology department and were analyzed and depicted in percentages. Sample processing, identification of organisms, and pattern of antimicrobial sensitivity were carried out as per the Clinical and Laboratory Standards Institute guidelines.Results: Out of 282 positive reports, Escherichia coli was the most common isolated uropathogen with a total of 148 (52.4%) followed by Klebsiella 72 (26%), 20 (7.9%) each of Citrobacter and pseudomonas aeruginosa. E. coli were resistant to nalidixic acid (59.5%), cotrimoxazole (58.1%), ciprofloxacin (54%) amoxyclav (52.7%), ampicilin (45.9%), cefatoxime (37.8%), cefaperazone and salbactum (25.3%). Klebsiella were resistant to amoxyclav (77.7%), cotrimazole (50%), nalidixic acid (41.6%), ampicilin (44.4%), cefatoxime (27.7%), ciprofloxacin (25%). E. coli and Klebsiella were highly susceptible to nitrofurantoin, cefaperazone and salbactum, piperacillin and tazobactum, amikacin, imipenem, gentamicin.Conclusions: The majority of the isolated bacteria were resistant to many antibiotics commonly used in clinical practices. So prior culture reports and institutional antibiograms are necessary for prescribing antibiotics rationally.

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