Antibiotic resistance of Vibrio parahaemolyticus and Vibrio vulnificus in various countries: A review

Abstract

Vibrio parahaemolyticus and Vibrio vulnificus are the leading causes of seafood associated infections and mortality in the United States. The main syndromes caused by these pathogens are gastroenteritis, wound infections, and septicemia. This article reviewed the antibiotic resistance profile of V. parahaemolyticus and V. vulnificus in the United States and other countries including Italy, Brazil, Philippines, Malaysia, Thailand, China, India, Iran, South Africa and Australia. The awareness of antimicrobial resistance of these two pathogens is not as well documented as other foodborne bacterial pathogens. Vibrio spp. are usually susceptible to most antimicrobials of veterinary and human significance. However, many studies reported that V. vulnificus and V. parahaemolyticus showed multiple-antibiotic resistance due to misuse of antibiotics to control infections in aquaculture production. In addition, both environmental and clinical isolates showed similar antibiotic resistance profiles. Most frequently observed antibiotic resistance profiles involved ampicillin, penicillin and tetracycline regardless of the countries. The presence of multiple-antibiotic resistant bacteria in seafood and aquatic environments is a major concern in fish and shellfish farming and human health.

Spreading of Pandemic Vibrio parahaemolyticus O3:K6 and Its Serovariants: A Re-analysis of Strains Isolated from Multiple Studies

“…Our results revealed similar antibiotic susceptibility profiles in pandemic ST3, ST88, and non-pandemic isolates. This finding was similar to that in the work of Elmahdi et al (2016). They concluded that the sampling location or month in which the samples were collected did not significantly impact V. parahaemolyticus resistance patterns because isolates from both environmental and clinical sources shared similar antibiotic resistance profiles.…”

“…They concluded that the sampling location or month in which the samples were collected did not significantly impact V. parahaemolyticus resistance patterns because isolates from both environmental and clinical sources shared similar antibiotic resistance profiles. Unsurprisingly, the majority of the isolates tested in this study showed ampicillin resistance, which is very common in V. parahaemolyticus isolates recovered from different sources (Sun et al, 2013; de Jesús Hernández-Díaz et al, 2015; Elmahdi et al, 2016; Mala et al, 2016). This result suggests that ampicillin should have a negligible role in the treatment of V. parahaemolyticus infection.…”

Mechanism of anti-Vibrio activity of marine probiotic strain Bacillus pumilus H2, and characterization of the active substance

“…In the past, vibriosis was controlled (prevented or treated) almost exclusively through application of antibiotics or chemotherapeutic agents, either as feed additives or in immersion baths. However, extensive use of this approach over time has resulted in increased resistance of pathogenic Vibrio strains to the commonly used antibiotics: ampicillin, amikacin, kanamycin, penicillin G, streptomycin, and tetracycline (Austin and Austin 2007; Li et al 1999; Elmahdi et al 2016). …”

“…In association with the rapid expansion of intensive mariculture and consequent deterioration of culture conditions, a steadily increasing number of Vibrio species are recognized as pathogens in vibriosis outbreaks (Austin and Zhang 2006; Cui et al 2014; Hou et al 2016). A limited number of antibiotics have been successfully applied, and resistance to these antibiotics may reduce the success of treatment programs (Al-Othrubi et al 2014; Elmahdi et al 2016). …”

Importance and implications of antibiotic resistance development in livestock and wildlife farming in South Africa: A Review

“…Seafood-associated infections is usually caused by V. cholera, V. parahaemolyticus and V. vulnificus (Raissy et al, 2012). Recent studies have shown that these species have become multidrug resistant (MDR) owing to the misuse of antibiotics in aquaculture production, and are thus major health threats to the public who become infected with seafood-borne diseases causes by antibiotic resistant Vibrio species (Elmahdi et al, 2016).…”