Antibiotic Resistance in Neisseria

Bash, Margaret C.; McKnew, Durrie L; Tapsall, John W.

doi:10.1007/978-1-60327-595-8_6

Cited by 4 publications

(2 citation statements)

References 162 publications

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“…The emergence of fluoroquinolone resistance in various species of Neisseria is particularly instructive. The prevalence of gonococcal ciprofloxacin resistance in China increased from 10% in 1996 to 95% in 2003 [6]. By way of contrast the median prevalence of ciprofloxacin resistance in 2009 was 24% in the Americas and 6% in Africa [7].…”

Section: Introductionmentioning

confidence: 99%

Positive Association between the Use of Quinolones in Food Animals and the Prevalence of Fluoroquinolone Resistance in E. coli and K. pneumoniae, A. baumannii and P. aeruginosa: A Global Ecological Analysis

Kenyon

2021

Antibiotics

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(1) Background: It is unclear what underpins the large global variations in the prevalence of fluoroquinolone resistance in Gram-negative bacteria. We tested the hypothesis that different intensities in the use of quinolones for food-animals play a role. (2) Methods: We used Spearman’s correlation to assess if the country-level prevalence of fluoroquinolone resistance in human infections with Acinetobacter baumannii, Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa was correlated with the use of quinolones for food producing animals. Linear regression was used to assess the relative contributions of country-level quinolone consumption for food-animals and humans on fluoroquinolone resistance in these 4 species. (3) Results: The prevalence of fluoroquinolone resistance in each species was positively associated with quinolone use for food-producing animals (E. coli [ρ = 0.55; p < 0.001], K. pneumoniae [ρ = 0.58; p < 0.001]; A. baumanii [ρ = 0.54; p = 0.004]; P. aeruginosa [ρ = 0.48; p = 0.008]). Linear regression revealed that both quinolone consumption in humans and food animals were independently associated with fluoroquinolone resistance in E. coli and A. baumanii. (4) Conclusions: Besides the prudent use of quinolones in humans, reducing quinolone use in food-producing animals may help retard the spread of fluoroquinolone resistance in various Gram-negative bacterial species.

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Section: Introductionmentioning

confidence: 99%

Positive Association between the Use of Quinolones in Food Animals and the Prevalence of Fluoroquinolone Resistance in E. coli and K. pneumoniae, A. baumannii and P. aeruginosa: A Global Ecological Analysis

Kenyon

2021

Antibiotics

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“…Why has gonococcal resistance to fluoroquinolones emerged so explosively in East Asia? The prevalence of ciprofloxacin resistance in China, for example, increased from 10% to 95% between 1996 and 2003 [1]. In comparison, the country-level median prevalence of ciprofloxacin resistance in 2009 was 24% in the Americas and 6% in Africa [2].…”

Section: Introductionmentioning

confidence: 99%

Association between quinolone use in food animals and gonococcal resistance to ciprofloxacin: an ecological study

González

Manoharan-Basil

Kenyon

2021

Preprint

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Positive Association between the Use of Quinolones in Food Animals and the Prevalence of Fluoroquinolone Resistance in E. Coli and K. Pneumoniae, A. Baumanii and P. Aeruginosa: A Global Ecological Analysis

Kenyon¹

2021

Preprint

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BackgroundIt is unclear what underpins the large global variations in the prevalence of fluoroquinolone resistance in gram-negative bacteria. We tested the hypothesis that different intensities in the use of quinolones for food-animals plays a role. MethodsWe used Spearman’s correlation to assess if the country-level prevalence of fluoroquinolone resistance in human infections with Acinetobacter baumannii, Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa was correlated with the use of quinolones for food producing animals. Linear regression was used to assess the relative contributions of country-level quinolone consumption for food-animals and humans on fluoroquinolone resistance in these 4 species. ResultsThe prevalence of fluoroquinolone resistance in each species was positively associated with quinolone use for food-producing animals (E. coli [ρ=0.55; P<0.001], K. pneumoniae [ρ=0.58; P<0.001]; A. baumanii [ρ=0.54; P=0.004]; P. aeruginosa [ρ=0.48; P=0.008]). Linear regression revealed that both quinolone consumption in humans and food animals were independently associated with fluoroquinolone resistance in E. coli and A. baumanii. ConclusionsReducing quinolone use in food-producing animals may help retard the spread of fluoroquinolone resistance in various gram negative bacterial species.

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Antibiotic Resistance in Neisseria

Cited by 4 publications

References 162 publications

Positive Association between the Use of Quinolones in Food Animals and the Prevalence of Fluoroquinolone Resistance in E. coli and K. pneumoniae, A. baumannii and P. aeruginosa: A Global Ecological Analysis

Positive Association between the Use of Quinolones in Food Animals and the Prevalence of Fluoroquinolone Resistance in E. coli and K. pneumoniae, A. baumannii and P. aeruginosa: A Global Ecological Analysis

Association between quinolone use in food animals and gonococcal resistance to ciprofloxacin: an ecological study

Positive Association between the Use of Quinolones in Food Animals and the Prevalence of Fluoroquinolone Resistance in <em>E. Coli</em> and <em>K. Pneumoniae, A. Baumanii</em> and <em>P. Aeruginosa</em>: A Global Ecological Analysis

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