Antibiotic Resistance: A Frightening Health Dilemma

Tiwari, Ruchi; Dhama, Kuldeep

doi:10.3844/ajptsp.2014.174.176

Cited by 8 publications

(3 citation statements)

References 17 publications

(15 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Superficial skin infections are primarily caused by aerobic micro-organism such as Staphylococcus, Streptococcus (Flesh eating bacteria), Vibrio or Aeromonas species, Corynebacteria spp., Pseudomonas aeruginosa, Pasteurella multocida and deeper wounds may be infected with anaerobic pathogens such as Bacteroides, Fusobacterium and Clostridium species. Bacterial infections are typically caused by colonizing normal flora and may also be by antibiotic resistant bacteria such as Methicillin Resistant Staphylococcus aureus (MRSA), Vancomycin Resistant Enterococcus faecium (VREF) and Extended Spectrum Beta lactamases (Watanabe, 1971;Duse, 1998;Boucher and Corey, 2008;Tiwari and Dhama, 2014). Fungal infections may arise later on as they are not inhibited by antibacterial treatment.…”

mentioning

confidence: 99%

Bacterial Etiology of Skin and Wound Infections along with Antibiogram Profiling in Reference to Emerging Antibiotic Resistance in Animals

Tiwari¹,

Yadav²,

Singh³

et al. 2015

Adv. Anim. Vet. Sci.

Self Cite

View full text Add to dashboard Cite

| The present study demonstrated bacterial etiology of skin affections and their antibiogram profiling of different animal species of various age groups. A total of 255 samples from cattle, buffalo, dogs, goats, sheep, camel and horses were collected over a period of two years (2012)(2013)(2014) from Mathura, (U.P.) India, and nearby surrounding areas. Clinical samples were collected from variety of skin disorders, subjected to laboratory isolation and identification as per standard protocols. The bacterial infection, Staphylococcus aureus, was the most common isolate (36.22 %), followed by E. coli (34.59 %), Pseudomonas (20.54), Bacillus (16.21), Klebsiella (12.43), Micrococcus spp (8.11 %), Streptococcus pyogens (7.56), Proteus (6.49), Clostridium (3.78), Gram negative non-lactose fermenter (2.7%), Gram positive non-spore producing bacilli (2.16) and Fusobacterium (0.54 %). Bacterial isolates obtained were subjected to in vitro antibiotic sensitivity testing by disc diffusion method against 23 commercially available antimicrobial discs. Results of the current study revealed maximum sensitivity to gatifloxacin (94.03%), amikacin (85.7%), mild sensitivity to sparfloxacin (44.85%) and gentamicin (43.48%); emergence of multi-drug resistant bacterial strains of Staphylococcus aureus, Pseudomonas aeruginosa, E.coli appeared to be an important finding. Present study is intended to document the complex microbial inhabitants of wounds from animals and their antimicrobial sensitivity pattern and strongly recommended the use of antimicrobial sensitivity testing to know the rapidly changing pattern of antibiotic activity. The study will further aid to the existing literature for planning new alternative therapeutic strategies against rising global health havoc of multidrug resistance.

show abstract

mentioning

confidence: 99%

Bacterial Etiology of Skin and Wound Infections along with Antibiogram Profiling in Reference to Emerging Antibiotic Resistance in Animals

Tiwari¹,

Yadav²,

Singh³

et al. 2015

Adv. Anim. Vet. Sci.

Self Cite

View full text Add to dashboard Cite

show abstract

“…Over time, microorganisms are developing resistance to the available antimicrobials, highlighting the urgent need to develop alternatives for treating these resilient microorganisms (Rudramurthy et al, 2016;Frieri et al, 2017;Kongkham et al, 2020;Larsson and Flach, 2021). Target-specific resistance has been developed against nearly every class of antibiotic (Schmieder and Edwards, 2012;Tiwari et al, 2013;Hassoun-Kheir et al, 2020;Stracy et al, 2022;He et al, 2022;Zhu et al, 2022). Due to drug resistance, antibiotics are frequently administered in high doses, leading to potential toxicity.…”

Section: Introductionmentioning

confidence: 99%

Green Synthesis and Characterization of Silver Nanoparticles from Ficus palmata Forssk. and Evaluation of their Antibacterial Activity Against Resistant Bacteria

Rehman,

Shumail,

Khalid

et al. 2023

J. Plant Environ.

View full text Add to dashboard Cite

In the present study, the synthesis and characterization of silver nanoparticles were carried out through a green chemistry approach. The purpose was to determine the antibacterial potential of environmentally safe nanoparticles against commonly reported resistant bacteria. The nanoparticles were synthesized using the aqueous extract of Ficus palmata Forssk. leaves. The active components present in the leaf extract acted as reducing and capping agents. The method used was easy, cost-effective, eco-friendly, and less time-consuming. To determine the shape, size, and crystalline nature, the nanoparticles underwent X-ray diffraction, and scanning electron microscopy. The synthesized nanoparticles were found to be crystalline in nature and spherical in shape, with an average diameter of about 30 nm. The antibacterial activity of the silver nanoparticles (20 µl) was evaluated against a range of antibiotic-resistant bacteria using standard microbiological procedures. They were found to be effective against MRSA, Bacillus subtilis, Staphylococcus aureus, and Klebsiella pneumonia.

show abstract

“…Antibiotic resistance in many bacteria including zoonotic salmonellas has been attributed to the injudicious use of antibiotics in food-producing animals with onward transmission to humans through the food chain (Threlfall, 2002;Tiwari and Dhama, 2014).…”

mentioning

confidence: 99%

Reduced Minimum Inhibitory Concentration of Antibiotics Associated with DT 104 Phage Type of Salmonella Enterica Serovar Typhimurium

Ahmad¹,

Agarwal²,

John³

et al. 2014

Adv. Anim. Vet. Sci.

View full text Add to dashboard Cite

Antibiotic Resistance: A Frightening Health Dilemma

Cited by 8 publications

References 17 publications

Bacterial Etiology of Skin and Wound Infections along with Antibiogram Profiling in Reference to Emerging Antibiotic Resistance in Animals

Bacterial Etiology of Skin and Wound Infections along with Antibiogram Profiling in Reference to Emerging Antibiotic Resistance in Animals

Green Synthesis and Characterization of Silver Nanoparticles from Ficus palmata Forssk. and Evaluation of their Antibacterial Activity Against Resistant Bacteria

Reduced Minimum Inhibitory Concentration of Antibiotics Associated with DT 104 Phage Type of Salmonella Enterica Serovar Typhimurium

Contact Info

Product

Resources

About