Antibiotic prophylaxis for prostate biopsy

Webb, Nathalie; Woo, Henry H.

doi:10.1046/j.1464-410x.2002.02735.x

Cited by 42 publications

(33 citation statements)

References 30 publications

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“…In 2007, 218,000 cases were diagnosed and approximately 27,000 of them died [12] . TRUSBP can cause mild complications as dysuria and perineal pain and life-threatening complications as hemorrhagia and infection [13] . As there are no strict criteria for biopsy decision, patient preparation and biopsy techniques can show variation.…”

Section: Discussionmentioning

confidence: 99%

Does Washing the Biopsy Needle with Povidone-Iodine Have an Effect on Infection Rates after Transrectal Prostate Needle Biopsy?

Koç¹,

Ün²,

Filiz³

et al. 2010

Urol Int

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Purpose: To determine the effect of washing the biopsy needle with povidone-iodine solution on infection rates after transrectal ultrasonography-guided prostate biopsy. Patients and Methods: 180 patients with transrectal prostate biopsy were included. Infection was excluded with midstream urine culture before biopsy, and patients were divided into two groups. In group 1 (n = 84), the needle was washed with povidone-iodine after each material reception during biopsy, and in group 2 (n = 96), it was not. At day 3 and 2 weeks after the biopsy, patients were checked. On day 3, midstream urine was cultured and patients were checked for fever, hematuria, rectal hemorrhagia, hematospermia and urinary retention. Also, the effect of rectal preparation on infection rate was evaluated. Results: There was no significant difference between the patients’ ages, PSA levels and prostate volumes. In total, 11 patients (6.1%; 4 from group 1 and 7 from group 2) developed infectious complications. There was no statistically significant difference between the groups. Fever, asymptomatic bacteriuria and urinary system infection rates were also not statistically different between the groups. The most frequent complication was hematuria with 83 cases (46.1%), but they did not need hospitalization and no patient had acute urinary obstruction. Conclusions: Washing the biopsy needle with povidone-iodine did not have an effect on the infection rates. Antibiotic prophylaxis and cleaning the biopsy equipment is adequate for low infection rates.

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Section: Discussionmentioning

confidence: 99%

Does Washing the Biopsy Needle with Povidone-Iodine Have an Effect on Infection Rates after Transrectal Prostate Needle Biopsy?

Koç¹,

Ün²,

Filiz³

et al. 2010

Urol Int

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“…[3,4] Generally infective complications which encounter us as asymptomatic bacteriuria can progress to urinary infection or sepsis. [9] Recently, thanks to developments of prebiopsy preparation of the patient, and biopsy technique, serious complication rates are at low levels. However, currently simple complication rates are still at considerable levels.…”

Section: Discussionmentioning

confidence: 99%

Comparison between ciprofloxacin and trimethoprim-sulfamethoxazole in antibiotic prophylaxis for transrectal prostate biopsy

Atılgan

Gençten

Kölükçü

et al. 2015

Turkish Journal of Urology

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Objective: The aim of this study was to compare the efficacies of oral ciprofloxacin administration and oral trimethoprim-sulfamethoxazole (TMP-SMX) regimens in preventing infectious complications following transrectal ultrasound guided biopsy of the prostate. Material and methods:Between 2011-2013, the medical records of 391 (mean age 64.62±7.64 years; range 40 to 87 years) patients who underwent transrectal prostate biopsies, due to suspicion of prostate cancer were retrospectively reviewed. While 500 mg ciprofloxacin was given orally twice daily starting one day before the procedure, continued for 3 days in the first 174 patients (group 1); was given orally twice daily starting one day before the procedure, continued for 3 days in the remaining 217 patients (group 2) for prophylaxis. Urine samples were obtained for urine culture before the procedure. The two groups were compared with respect to findings of urine cultures performed before and after the procedure and complications. Results:In the ciprofloxacin and groups, any positive urine culture before the procedure was not observed. Complications occured in 93 patients (37 in group 1 and 56 in group 2), after the procedure. Twenty-two (5.6%) (11 in group 1 and 11 in group 2). patients were admitted to our clinic because of high fever occurring after biopsy. Nine ciprofloxacin-treated (5.2%) and 16 TMP-SMX-treated (7.4%) patients had severe dysuria after the procedure. Twenty-one ciprofloxacin recipients (12.1%) and 40 TMP-SMX recipients (18.4%) had macroscopic hematuria. In the ciprofloxacin and TMP-SMX groups, the incidences of new culture positivity were 4% (n=7) and 2.8% (n=6) after the procedure, respectively. All of the isolated bacteria was Escherichia coli. While 11 patients were hospitalized due to signs of complicated urinary tract infections, and 2 patients were treated as outpatients. Rectal bleeding that did not require any intervention was observed in a patient 8 hours after biopsy. SIRS findings were detected in two patients. There were no significant differences between the two groups with respect to age, prostate volume, prostate spesific antigen (PSA) levels, and results of urine culture performed after the procedure (p>0.05). Conclusion:Despite the increasing resistance to antibiotics, ciprofloxacin and TMP-SMX are effective prophylactic treatment modalities for transrectal prostate biopsy. Both three-day ciprofloxacin and TMP-SMX regimens seem to be equally effective in the antibiotic prophylaxis for transrectal prostate biopsy.

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“…We used a Siemens SI-400 ultrasound device with biplane transrectal probe Siemens Patients took laxatives for one day and fluoroquinolone therapy for five days prior to biopsy, as recommended by Webb and Woo 20 and Sieber et al 21 Transrectal ultrasound and biopsy were performed in standard position without anesthesia. DRE was performed first, followed by the measurement of prostate volume.…”

Section: Methodsmentioning

confidence: 99%

The Incidence of Hyperechoic Prostate Cancer in Transrectal Ultrasound–Guided Biopsy Specimens

Spajić¹,

Eupic

Tomas

et al. 2007

Urology

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Antibiotic prophylaxis for prostate biopsy

Cited by 42 publications

References 30 publications

Does Washing the Biopsy Needle with Povidone-Iodine Have an Effect on Infection Rates after Transrectal Prostate Needle Biopsy?

Does Washing the Biopsy Needle with Povidone-Iodine Have an Effect on Infection Rates after Transrectal Prostate Needle Biopsy?

Comparison between ciprofloxacin and trimethoprim-sulfamethoxazole in antibiotic prophylaxis for transrectal prostate biopsy

The Incidence of Hyperechoic Prostate Cancer in Transrectal Ultrasound–Guided Biopsy Specimens

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