Antibiotic prevention of infective endocarditis due to oral procedures: myth, magic, or science?

Sakamoto, Haruo; Karakida, Kazunari; Otsuru, Mitsunobu; Aoki, Takayuki; Hata, Yoshiki; Aki, Akira

doi:10.1007/s10156-007-0537-4

Cited by 9 publications

(6 citation statements)

References 74 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However no prospective randomized placebo-controlled trials exist on the efficacy of antibiotic prophylaxis to prevent infective endocarditis in patients who undergo a dental procedure. 50 Bacteremia can occur following brushing teeth and even from chewing food. 51 Because of a lack of proven benefit from using antibiotic prophylaxis and because it is now recognized that bacteremia can occur following routine daily activities, maintaining good oral hygiene is increasingly being emphasized as the primary means of limiting the development of this highly morbid disease.…”

Section: Preventing Nonoral Infections By Using Antibiotic Prophylaxi...mentioning

confidence: 99%

The Prevention of Infections in Older Adults: Oral Health

Coll

Lindsay

Meng

et al. 2019

J American Geriatrics Society

View full text Add to dashboard Cite

The oral cavity is exposed to the external environment and from a very young age is colonized by infectious agents. Under certain circumstances including poor oral hygiene, dry mouth, trauma, and the use of antibiotics, oral infections can occur. They can result in damage to the oral cavity including teeth and their support structures. Oral infections can also lead to the extension of infection into surrounding tissues and to systemic infections. Chronic oral infection is a recognized risk factor for heart disease. Older adults are at high risk for oral infections and associated complications. Tooth loss, for which infection is the most significant cause, leads to cosmetic changes and a decreased ability to masticate certain foods that can lead to malnutrition. Chronic oral infections and the manipulation of teeth and supporting structures can lead to the hematogenous spread of infection including the infection of artificial joints and endocardial implants. Good oral hygiene, the use of fluoride, regular dental care, and the appropriate use of antibiotics can all reduce oral infections and their associated complications. J Am Geriatr Soc 68:411–416, 2020

show abstract

Section: Preventing Nonoral Infections By Using Antibiotic Prophylaxi...mentioning

confidence: 99%

The Prevention of Infections in Older Adults: Oral Health

Coll

Lindsay

Meng

et al. 2019

J American Geriatrics Society

View full text Add to dashboard Cite

show abstract

“…In common inflammatory conditions such as gingivitis and chronic periodontitis, the periodontal vasculature proliferates and dilates, producing an even greater surface area and facilitating the entry of microorganisms into the bloodstream (Parahitiyawa et al 2009). Consequently, it has been assumed that the patients with periodontal disease may have a much higher risk of developing B-EOA and, hence, systemic diseases of oral origin (Gendron et al 2000, Li et al 2000, Carmona et al 2002Sakamoto et al 2007, Olsen 2008, Bolger 2009). Even some Expert Committee guidelines concurred with the premise: "Maintenance of optimal oral hygiene and periodontal health may reduce the incidence of B-EOA and is more important than prophylactic antibiotics for a dental procedure to reduce the risk of IE" (Wilson et al 2007, National Institute for Health andClinical Excellence 2008).…”

mentioning

confidence: 99%

Periodontal health status and bacteraemia from daily oral activities: systematic review/meta‐analysis

Tomás

Dios

Tobías

et al. 2011

J Clinic Periodontology

242

232

View full text Add to dashboard Cite

show abstract

“…Sin embargo, a pesar de que estas recomendaciones son seguidas mayoritariamente, no existen ensayos clínicos controlados aleatorizados prospectivos a gran escala publicados que muestren la eficacia de la profilaxis antibió tica. Por ello, estas prá cticas han sido criticadas duramente 23 .…”

Section: Relationship Between Odontogenic Infections and Infective Enunclassified