Antibiotic prescriptions to adults with acute respiratory tract infections by Italian general practitioners

Bianco, Aida; Papadopoli, Rosa; Mascaro, Valentina; Pileggi, Claudia; Pavia, Marco

doi:10.2147/idr.s170349

Cited by 43 publications

(46 citation statements)

References 32 publications

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“…For the fi rst two MCD, macrolide antibiotic was predominantly prescribed. Similar results were obtained in a study conducted in Italy where the MCD was acute pharyngitis (60.4%) and the second most frequent was acute bronchitis (18.2%) [11]. Globally, acute sinusitis in adults is usually of viral etiology.…”

Section: Discussionsupporting

confidence: 86%

“…In a study conducted in Italy in 2017, the most commonly prescribed were macrolides (32.5%), broad-spectrum penicillins (31.1%) and fl uoroquinolones (14.2%) [11]. Italy is a country with a high consumption of antibiotics [26], especially for prophylactic purposes [27] and one of the countries with the fastest growth of antibiotic resistance [28].…”

Section: Discussionmentioning

confidence: 99%

“…It is estimated that the European Union has been losing 1.5 billion euros annually at the expense of age-related bacterial resistance [10]. Considering that the vast majority of antibiotics are prescribed in primary care [11], we have decided to examine what prescribing practice is present in our country. National guidelines are contained in Pharmacotherapy Protocols in Primary Health Care -the most common diseases and conditions from 2014.…”

Section: Introductionmentioning

confidence: 99%

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The antibiotic prescription practice in primary health care from the pharmacist perspective

Čović¹,

Todorović²,

Čanji³

et al. 2019

Hosp Pharm Int Multi J

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Introduction: Antibiotic resistance is a growing problem. Adherence to national guidelines is one of the key factors necessary for the rational use of antibiotics. Aim: The aim of the study was to examine characteristics of antibiotic prescribing practice in primary health care in Novi Sad. Method: The analysis was designed as a descriptive, cross-sectional study based on the data obtained from the health institution Cvejić Pharmacy. The guidelines available to physicians at the time of prescribing were used to assess the compliance of the prescribed antibiotics with the guidelines. Additionally, the most frequently dispensed antibiotics for all diagnoses were recorded and results were expressed as a percentage of frequency of analyzed antibiotic prescriptions. Results: The study has shown that antibiotic prescriptions make 5.48% of all prescriptions (719 out of 13115), 513 (71.35%) of which were established by national guidelines, and 206 (28.65%) for less frequent diagnoses which was not included in national guidelines. In the study sample, 297 (65.42%) terapeutical regimes had adequate terapeutical dosage. The most commonly prescribed antibiotic groups were: macrolides (35.18%), penicillins (28.68%) and cephalosporins (14.60%). Conclusions: Irrational prescribing and dispensing of antibiotics is both national and global problem. It is necessary to pay close attention to antibiotics prescribing and dispensing. The focus should be on national guidelines and their extension.

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Section: Discussionsupporting

confidence: 86%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The antibiotic prescription practice in primary health care from the pharmacist perspective

Čović¹,

Todorović²,

Čanji³

et al. 2019

Hosp Pharm Int Multi J

View full text Add to dashboard Cite

show abstract

“…Indeed, it could lead to the patient demand for antibiotics for viral infections, such as acute respiratory tract infections (RTIs) that are frequent reasons for medical consultation in general practice and are commonly caused by viruses and do not require antibiotics. Indeed a very high frequency of nonevidence-based prescription of antibiotics at primary care among the adult population with RTIs was reported in the same area [ 26 ].…”

Section: Discussionmentioning

confidence: 99%

Knowledge and practices regarding antibiotics use

Bianco

Licata

Zucco

et al. 2020

Evolution, Medicine, and Public Health

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Background and objectives This study aimed to assess the knowledge of antibiotics and antimicrobial resistance (AMR) and the antibiotic use among the general public in Southern Italy and to analyze whether socio-demographic characteristics could be associated with poor knowledge and improper practices. Methodology From March to November 2019, a face to face interview was conducted with adult subjects attending the waiting room of 27 randomly selected general practitioners (GPs) in Southern Italy. The questionnaire covered socio-demographic characteristics, knowledge of antibiotics and AMR and practices regarding the consumption of and self-medication with antibiotics. Results The response rate was 89.7%. In the sample, 29.2% thought that antibiotics are effective for viral infections and 49.5% correctly recognized the definition of AMR. Predictors of good knowledge about antibiotics and AMR were female gender and a higher education level. Almost half of the respondents had used antibiotics in the previous year and 23.6% took antibiotics to treat a common cold and/or fever. Among participants, 25.5% reported to have bought antibiotics without a prescription, and 30.6% were classified as antibiotic self-medication users. Use of antibiotics in the previous 12 months and having taken an antibiotic after a phone consultation with the GP were positively associated with both antibiotic use for a common cold and/or fever and self-medication with antibiotics. Conclusions and implication The findings of this study highlighted a considerable antibiotic consumption in the adult population of Southern Italy together with misconceptions regarding the correct indication for antibiotic use that could foster indiscriminate antibiotic use. Lay summary The findings of this study highlighted a considerable antibiotic consumption in the adult Italian population together with misconceptions regarding the correct indication for antibiotic use that could foster indiscriminate antibiotic use. Almost a quarter of the respondents took antibiotics to treat a common cold and/or fever, and reported to have bought antibiotics without a prescription.

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“…Aus deutschen Allgemeinarztpraxen wurde berichtet, dass rund die Hälfte der Antibiotikaverordnungen bei Atemwegsinfektionen nicht leitlinienkonform erfolgen [5]. In Italien waren dies in einer Studie > 70 % hinsichtlich der Substanzauswahl [6]. In den Niederlanden hat man speziell bei (höchstwahrscheinlich) viralen Atemwegsinfektionen in der Situation Notfallpraxis/Notfallaufnahme in rund 50 % der Fälle (nicht angezeigte) Antibiotikaverordnungen beobachtet [7].…”

Section: Ambulanter Bereich Und Pflegeheimeunclassified

Fehler und Optimierungsbereiche bei der Verordnung von Antibiotika

Kern¹

2020

Dtsch Med Wochenschr

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Inadequate antibiotic prescribing has been observed in many settings both in hospitals as well as in primary care. Most often there is uncertainty about the indication for antibiotic treatment itself, prescribers are reluctant to deescalate, and therapy duration is too long which results most often in overprescribing. The burden of overprescribing is difficult to estimate, but many studies in the hospital setting report a rate of approximately 30 % of inadequate prescribing – with wide variation. Over- but also underprescribing of antimicrobial agents is a serious patient safety issue that needs to be addressed in specific programmes at different levels of the healthcare system. Interventional studies have shown that programmes implementing or intensifying audit and feedback with clinical reevaluation by experts can be very efficient to reduce inadequate prescribing.

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Antibiotic prescriptions to adults with acute respiratory tract infections by Italian general practitioners

Cited by 43 publications

References 32 publications

The antibiotic prescription practice in primary health care from the pharmacist perspective

The antibiotic prescription practice in primary health care from the pharmacist perspective

Knowledge and practices regarding antibiotics use

Fehler und Optimierungsbereiche bei der Verordnung von Antibiotika

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