Antibiotic Prescription Practices for Surgical Prophylaxis in India: An Observational Study

Anand, Sanu; Raman, Dileep; Shetty, Divya; Joshi, Dhruv; Hamsaveni, C. G.; Unnikrishnan, Dileep

doi:10.4269/ajtmh.19-0267

Cited by 4 publications

(2 citation statements)

References 8 publications

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“…It is noticed that a large number males underwent surgery and received prophylactic antibiotics. The result is consistent to previous studies and contrary to other studies wherein more number of females than males underwent surgery and received antibiotics [17,[22][23][24]. Furthermore, the age group 31-45 years had the most antibiotic exposure, followed by 46-60 years, indicating that these age groups had the most surgical procedures.…”

Section: Discussionsupporting

confidence: 90%

Hospital Antibiotic Prescribing Pattern in General Surgery Specialty: Analysis Based on the WHO Access, Watch and Reserve (AWaRe) Classification

Mounika¹,

Juveriya²,

Uppu³

et al. 2021

JPRI

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Background: Surgical site infections are a prevalent cause of nosocomial infections that require antibiotic prophylaxis. Emergence and spread of antimicrobial resistance is a major global public health issue that must be addressed. Eventually, antibiotic prescribing pattern should be examined in order to ensure that antibiotics are used appropriately and that their effectiveness is preserved. Objective: To evaluate hospital antibiotic prescribing pattern emphasizing on cephalosporins in general surgery specialty using the WHO Access, Watch, and Reserve (AWaRe) classification. Methodology: A cross-sectional study was carried out in 658 hospitalized patients who received prophylactic antibiotics in general surgery specialty for six months. The data were analysed using the ‘WHO prescribing indicators’ and examined for the WHO ‘AWaRe’ categories. The acquired data was subjected to descriptive statistics. Results: Per encounter, the average number of drugs and antibiotics prescribed were 3.8 and 1.3, respectively. 83.4% encounters were with at least one antibiotic and 94.5% encounters had parenteral antibiotics. 31.3% and 77.8% antibiotics were prescribed by generic name and from the Essential Medicines List, respectively. The most frequently prescribed antibiotics were the third generation cephalosporins (36.8%) wherein ceftriaxone (22.0%) and cefoperazone (7.2%) were the two most commonly prescribed. A total of 14 specific antibiotics, ‘Access’ 5 and ‘Watch’ 9 were prescribed. Based on the WHO AWaRe classification, 42.3% ‘Access’ and 57.7% ‘Watch’ group antibiotics prescribed. All the prescribed cephalosporins (100%) were from the ‘Watch’ category. Amikacin (13.5%) and ceftriaxone (22.0%) were the most commonly prescribed ‘Access’ and ‘Watch’ group antibiotics, respectively. Amoxicillin index was 7.5 and ‘Access-to-Watch’ index was 0.7, which were much below the priority values. Conclusion: The antibiotic prescription pattern seen in this study did not entirely meet the WHO recommendations. Antibiotics from the ‘Watch’ category, notably cephalosporins, were commonly prescribed. To retain antibiotic effectiveness and encourage rational antibiotic use, as well as to overcome antibiotic resistance, changes and surveillance antibiotics prescribing are required.

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Section: Discussionsupporting

confidence: 90%

Hospital Antibiotic Prescribing Pattern in General Surgery Specialty: Analysis Based on the WHO Access, Watch and Reserve (AWaRe) Classification

Mounika¹,

Juveriya²,

Uppu³

et al. 2021

JPRI

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“…In this study a total of 180 patients undergoing post-operative care were included. [11][12][13][14] In gender wise distribution 98 (54.44%) patients were diagnosis (48/90) followed by colorectal cases (20/90) and other gastro duodenal procedures (12/90). Majority of prophylaxis antibiotic (90%) was administered by intravenous route and only 10% was administered by oral route.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Prescription Pattern of Antibiotic for Surgical Prophylaxis Use in a Tertiary Care Hospital

Vigneswaran¹,

Cresenciya²,

Jeevithalakshmi³

et al. 2023

Ind. J. Pharm. Pract.

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Objectives:The aim of this study was to evaluate the utilization pattern of antibiotics for surgical prophylaxis in patients undergone surgery at Government District Headquarters Hospital, Virudhunagar. Materials and Methods: This study was conducted for 6months (May-October 2021). Patients who were more than 18 years of age admitted in general surgical, orthopedic and gynecology wards receiving at least one dose of any class of antibiotics orally or intravenously were included in this study. Results: A total of 180 patients were undergoing post operative care during the study period in surgery ward of Government Headquarters Hospital, Virudhunagar. Among 180 patients 34% (62) patients were aged between 31 to 45, 32% (58) patients were aged between 46-60, 18% (32) patients were aged between 18-30, 13% (24) patients were between 61-75, 2% (4) patients were aged between 76-90. Conclusion: Reduction of surgical site infections decreases the post-operative morbidity, mortality rate. Combination therapy of antibiotic use gives more success in treat infection when compared with monotherapy use of antibiotics.

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Overview of COVID-19 Pandemic: Its Management and Prevention in Light of the Indian Traditional Medicine System

Singh

Yadav

et al. 2023

CTM

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With the global death toll nearing 3.3 million, India being amongst the top 4 countries, the condition is more than fearsome. World Health Organization (WHO) recommends one doctor per 1000 population ratio, but India lags it by one doctor to 1456 people, which sets a lot of pressure on the healthcare system. Traditional remedies are becoming increasingly popular in India as a result of the lack of a proper medical system. Due to the rich diversity of medicinal herbs and drugs; India has been managing health issues with its 5000 years old medication system. Amidst all this, the traditional medicine system has given relief to plenty of diseases and remains the primary defence system against COVID-19. Therefore, COVID-19 is also managed by its different medicinal systems, which are collectively known as the AYUSH regime. It had been a recognized system to tackle diseases in the past. In this mini-review, we performed a deep study of the Indian traditional medicine system in managing the COVID-19 situation.

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Antibiotic Prescription Practices for Surgical Prophylaxis in India: An Observational Study

Cited by 4 publications

References 8 publications

Hospital Antibiotic Prescribing Pattern in General Surgery Specialty: Analysis Based on the WHO Access, Watch and Reserve (AWaRe) Classification

Hospital Antibiotic Prescribing Pattern in General Surgery Specialty: Analysis Based on the WHO Access, Watch and Reserve (AWaRe) Classification

Evaluation of Prescription Pattern of Antibiotic for Surgical Prophylaxis Use in a Tertiary Care Hospital

Overview of COVID-19 Pandemic: Its Management and Prevention in Light of the Indian Traditional Medicine System

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