Antibiotic Potential of Endophytic Actinomycetes of Medicinal Herbs Against Human Pathogenic Bacteria

Chandrakar, Sandhya; Gupta, A. K.

doi:10.1007/s40011-015-0668-9

Cited by 13 publications

(2 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In addition, TCM herbs can inhibit the growth of pathogenic microorganisms, especially the harmful bacteria in the intestinal tract (Wang et al, 2010;Xuan et al, 2014;Chandrakar et al, 2015). This study also proved that treatments LM and LMT significantly inhibited the growth of Prevotella, Alloprevotella, and Clostridium.…”

Section: Discussionmentioning

confidence: 59%

Effects of a traditional Chinese medicine formula containing the Coix seed and Lotus seed on the intestinal morphology and microbiota of local piglets

Lin

Zheng

et al. 2021

AMB Expr

View full text Add to dashboard Cite

A traditional Chinese medicine formula based on the Coix seed and Lotus seed has been used as a general treatment of malnutrition, excessive fatigue, dysfunction of the spleen and stomach, and disorders of water transport in humans in China. However, there is limited information on its effects on the gut microbiota of piglets in vivo. In this study, the mix of Coix seed and Lotus were added the diet of forty weaned piglets (local piglets), and then evaluated it’s affected on the gut microbiota of piglets and on the relations within the gut bacterial community. The results indicated that this traditional Chinese medicine formula (LM) and the extract of the traditional Chinese medicine formula (LMT) downregulated pH of succus gastricus and raised pH of the ileum, and LMT obviously decreased the feed conversion ratio. Further study showed LMT and LM also significantly increased the thick and long of gastrointestinal villi. And then, 16S ribosomal DNA sequencing revealed that groups LMT and LM have higher relative abundance of the genus Lactobacillus in the colon, succus gastricus, and jejunum, which are beneficial bacteria sold as dietary supplements to aid digestion or to augment health. Meanwhile, the relative abundance levels of Prevotellaceae, Alloprevotella, and Prevotella in the colon and Clostridium in succus gastricus and jejunum were lower. These experiments highlight the usefulness of the traditional Chinese medicine formula based on the Coix seed and Lotus seed for decreasing pH in succus gastricus, for improving the structure of intestinal villi and gut microflora, and then for achieving improvements in pig production performance.

show abstract

Section: Discussionmentioning

confidence: 59%

Effects of a traditional Chinese medicine formula containing the Coix seed and Lotus seed on the intestinal morphology and microbiota of local piglets

Lin

Zheng

et al. 2021

AMB Expr

View full text Add to dashboard Cite

show abstract

“…strain HSTU-ABk15 possessing growth inhibitor traits against S. epidermidis can serve as sources of novel antibiotics [ 58 ]. Bacterial strains, such as the Bacillus sp., Lysinibacillus , Streptomyces , Streptomyces parvulus Av-R5, also had anti-bacterial activity against S. aureus [ 59 , 60 , 61 , 62 , 63 ]. Endophytes are also the storehouse of several kinds of bioactive metabolites, including phenolics, alkaloids, quinones, steroids, saponins, tannins, and terpenoids, which makes them serve as potential anti-cancer, anti-malarial, anti-tuberculosis, anti-viral, anti-diabetic, anti-inflammatory, anti-arthritis, and immunosuppressive agents, as well as helping host plants become more resistant to abiotic and biotic stresses [ 64 ].…”

Section: Discussionmentioning

confidence: 99%

Characterization of Growth-Promoting Activities of Consortia of Chlorpyrifos Mineralizing Endophytic Bacteria Naturally Harboring in Rice Plants—A Potential Bio-Stimulant to Develop a Safe and Sustainable Agriculture

Prodhan

Rahman

et al. 2023

Microorganisms

View full text Add to dashboard Cite

Eighteen pesticide-degrading endophytic bacteria were isolated from the roots, stems, and leaves of healthy rice plants and identified through 16S rRNA gene sequencing. Furthermore, biochemical properties, including enzyme production, dye degradation, anti-bacterial activities, plant-growth-promoting traits, including N-fixation, P-solubilization, auxin production, and ACC-deaminase activities of these naturally occurring endophytic bacteria along with their four consortia, were characterized. Enterobacter cloacae HSTU-ABk39 and Enterobacter sp. HSTU-ABk36 displayed inhibition zones of 41.5 ± 1.5 mm, and 29 ± 09 mm against multidrug-resistant human pathogenic bacteria Staphylococcus aureus and Staphylococcus epidermidis, respectively. FT-IR analysis revealed that all eighteen isolates were able to degrade chlorpyrifos pesticide. Our study confirms that pesticide-degrading endophytic bacteria from rice plants play a key role in enhancing plant growth. Notably, rice plants grown in pots containing reduced urea (30%) mixed with either endophytic bacterial consortium-1, consortium-2, consortium-3, or consortia-4 demonstrated an increase of 17.3%, 38.6%, 18.2%, and 39.1% yields, respectively, compared to the control plants grown in pots containing 100% fertilizer. GC–MS/MS analysis confirmed that consortia treatment caused the degradation of chlorpyrifos into different non-toxic metabolites, including 2-Hydroxy-3,5,6 trichloropyridine, Diethyl methane phosphonate, Phorate sulfoxide, and Carbonochloridic. Thus, these isolates could be deployed as bio-stimulants to improve crop production by creating a sustainable biological system.

show abstract

Screening of Endophytes for Antibacterial Properties

Veerapagu¹,

Jeya²,

Sankaranarayanan³

2022

Springer Protocols Handbooks

View full text Add to dashboard Cite

Antibiotic Potential of Endophytic Actinomycetes of Medicinal Herbs Against Human Pathogenic Bacteria

Cited by 13 publications

References 25 publications

Effects of a traditional Chinese medicine formula containing the Coix seed and Lotus seed on the intestinal morphology and microbiota of local piglets

Effects of a traditional Chinese medicine formula containing the Coix seed and Lotus seed on the intestinal morphology and microbiota of local piglets

Characterization of Growth-Promoting Activities of Consortia of Chlorpyrifos Mineralizing Endophytic Bacteria Naturally Harboring in Rice Plants—A Potential Bio-Stimulant to Develop a Safe and Sustainable Agriculture

Screening of Endophytes for Antibacterial Properties

Contact Info

Product

Resources

About