Antibiotic-loaded lactoferrin nanoparticles as a platform for enhanced infection therapy through targeted elimination of intracellular bacteria

Wang, Wei; Mo, Wanying; Xiao, Xue; Cai, Manying; Feng, Songfu; Wang, Yupeng; Zhou, Dongfang

doi:10.1016/j.ajps.2024.100926

Cited by 3 publications

(1 citation statement)

References 48 publications

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“…Developed nanotechnology has also brought significant impetus to the pharmaceutical and medical fields, bringing new diagnosis or treatment methods for many diseases, such as cancer, 16–18 acquired immune deficiency syndrome (AIDS), 19 tuberculosis, 20 osteoarthritis 21,22 and infection. 23,24 As mentioned earlier, due to the lack of special and effective treatment methods for ICH, it forces researchers to seek new treatment methods. In addition to relying on surgery to reduce the mortality rate due to ICH, many studies are currently seeking breakthroughs in secondary injury and functional recovery after ICH.…”

Section: Introductionmentioning

confidence: 99%

Application of biomaterials in the treatment of intracerebral hemorrhage

Wang,

Liu,

Wang

et al. 2024

Biomater. Sci.

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Section: Introductionmentioning

confidence: 99%

Application of biomaterials in the treatment of intracerebral hemorrhage

Wang,

Liu,

Wang

et al. 2024

Biomater. Sci.

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Manipulation of protein corona for nanomedicines

Li,

Wang,

Zhou

2024

WIREs Nanomed Nanobiotechnol

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Nanomedicines have significantly advanced the development of diagnostic and therapeutic strategies for various diseases, while they still encounter numerous challenges. Upon entry into the human body, nanomedicines interact with biomolecules to form a layer of proteins, which is defined as the protein corona that influences the biological properties of nanomedicines. Traditional approaches have primarily focused on designing stealthy nanomedicines to evade biomolecule adsorption; however, due to the intricacies of the biological environment within body, this method cannot completely prevent biomolecule adsorption. As research on the protein corona progresses, manipulating the protein corona to modulate the in vivo behaviors of nanomedicines has become a research focus. In this review, modern strategies focused on influencing the biological efficacy of nanomedicines in vivo by manipulating protein corona, along with their wide‐ranging applications across diverse diseases are critically summarized, highlighted and discussed. Finally, future directions for this important yet challenging research area are also briefly discussed.This article is categorized under: Nanotechnology Approaches to Biology > Nanoscale Systems in Biology Therapeutic Approaches and Drug Discovery > Emerging Technologies Biology‐Inspired Nanomaterials > Protein and Virus‐Based Structures

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Research Interest in Copper Materials for Caries Management: A Bibliometric Analysis

Xu,

Nizami,

Yin

et al. 2024

JFB

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This study examined research interest in copper materials for caries management. We conducted an exhaustive literature search of English publications on copper materials for caries management. We removed duplicate publications and screened the titles and abstracts to identify relevant publications. Then, we analyzed the bibliometric data of the publications using the Bibliometrix and VOSviewer programs. This study included 75 laboratory studies, six clinical trials, and 17 reviews. Most of the original research studied copper or copper oxide nanoparticles (45/81, 56%). The materials could be doped into topical agents, restorative fillers, dental adhesives, dental implants, and orthodontic appliances. Since the first paper was published in 1980, publication counts gradually increased and surged in 2019. Among publications on copper materials for caries management, the publication counts and citations from 2019 to 2024 accounted for 65% (64/98) and 74% (1677/2255) over the last 45 years. Cocitation analysis revealed that the two main keywords were nanoparticles and antibacterial activity, and their burst strengths (period) were 3.84 (2021–2024) and 2.21 (2020–2021). The topics of the top two publications with the highest citation burst strength (period) are the antimicrobial effect of copper oxide nanoparticles (3.14, 2021–2022) and the dental application of copper nanoparticles (2.84, 2022–2024). In conclusion, this study revealed a growing interest in copper materials for caries management.

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Antibiotic-loaded lactoferrin nanoparticles as a platform for enhanced infection therapy through targeted elimination of intracellular bacteria

Cited by 3 publications

References 48 publications

Application of biomaterials in the treatment of intracerebral hemorrhage

Application of biomaterials in the treatment of intracerebral hemorrhage

Manipulation of protein corona for nanomedicines

Research Interest in Copper Materials for Caries Management: A Bibliometric Analysis

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