Antibiotic-Impregnated Catheters Associated With Significant Decrease in Nosocomial and Multidrug-Resistant Bacteremias in Critically Ill Patients

Hanna, Hend; Raad, Issam; Hackett, Brenda; Wallace, Susannah Kish; Price, Kristen; Coyle, David; Parmley, C. Lee

doi:10.1378/chest.124.3.1030

Cited by 75 publications

(37 citation statements)

References 28 publications

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“…Use antiseptic-or antimicrobial-impregnated CVCs for adult patients (A-I). [64][65][66][67][68][69][70] a. The risk of CLABSI is reduced with some currently marketed catheters impregnated with antiseptics (eg, chlorhexidine-silver sulfadiazine) or antimicrobials (eg, minocycline-rifampin).…”

Section: Special Approaches For the Prevention Of Clabsimentioning

confidence: 99%

Strategies to Prevent Central Line–Associated Bloodstream Infections in Acute Care Hospitals

Marschall

Mermel

Classen

et al. 2008

Infect. Control Hosp. Epidemiol.

384

251

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Previously published guidelines are available that provide comprehensive recommendations for detecting and preventing healthcare-associated infections. The intent of this document is to highlight practical recommendations in a concise format designed to assist acute care hospitals in implementing and prioritizing their central line–associated bloodstream infection (CLABSI) prevention efforts. Refer to the Society for Healthcare Epidemiology of America/Infectious Diseases Society of America “Compendium of Strategies to Prevent Healthcare-Associated Infections” Executive Summary and Introduction and accompanying editorial for additional discussion.1. Patients at risk for CLABSIs in acute care facilitiesa. Intensive care unit (ICU) population: The risk of CLABSI in ICU patients is high. Reasons for this include the frequent insertion of multiple catheters, the use of specific types of catheters that are almost exclusively inserted in ICU patients and associated with substantial risk (eg, arterial catheters), and the fact that catheters are frequently placed in emergency circumstances, repeatedly accessed each day, and often needed for extended periods.b. Non-ICU population: Although the primary focus of attention over the past 2 decades has been the ICU setting, recent data suggest that the greatest numbers of patients with central lines are in hospital units outside the ICU, where there is a substantial risk of CLABSI.2. Outcomes associated with hospital-acquired CLABSIa. Increased length of hospital stayb. Increased cost; the non-inflation-adjusted attributable cost of CLABSIs has been found to vary from $3,700 to $29,000 per episode

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Section: Special Approaches For the Prevention Of Clabsimentioning

confidence: 99%

Strategies to Prevent Central Line–Associated Bloodstream Infections in Acute Care Hospitals

Marschall

Mermel

Classen

et al. 2008

Infect. Control Hosp. Epidemiol.

384

251

View full text Add to dashboard Cite

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“…When estimating the extra cost of a CRBSI, four of the 16 studies 40,85,86,87 refer to the paper by Pittet and colleagues. 88 This paper reports a pairwise-matched case-control study designed to determine the excess length of stay, extra costs and mortality attributable to nosocomial BSI in critically ill patients.…”

Section: Extra Cost Of a Crbsimentioning

confidence: 99%

The clinical effectiveness and cost-effectiveness of central venous catheters treated with anti-infective agents in preventing bloodstream infections: a systematic review and economic evaluation

Hockenhull¹,

Dwan²,

Boland³

et al. 2008

Health Technol Assess

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Non-UK purchasers will have to pay a small fee for post and packing. For European countries the cost is £2 per monograph and for the rest of the world £3 per monograph.You can order HTA monographs from our Despatch Agents:-fax (with credit card or official purchase order) -post (with credit card or official purchase order or cheque) -phone during office hours (credit card only).Additionally the HTA website allows you either to pay securely by credit card or to print out your order and then post or fax it. NHS libraries can subscribe free of charge. Public libraries can subscribe at a very reduced cost of £100 for each volume (normally comprising 30-40 titles). The commercial subscription rate is £300 per volume. Please see our website for details. Subscriptions can only be purchased for the current or forthcoming volume. Contact details are as follows: Payment methods Paying by chequeIf you pay by cheque, the cheque must be in pounds sterling, made payable to Direct Mail Works Ltd and drawn on a bank with a UK address. Paying by credit cardThe following cards are accepted by phone, fax, post or via the website ordering pages: Delta, Eurocard, Mastercard, Solo, Switch and Visa. We advise against sending credit card details in a plain email. Paying by official purchase orderYou can post or fax these, but they must be from public bodies (i.e. NHS or universities) within the UK. We cannot at present accept purchase orders from commercial companies or from outside the UK. How do I get a copy of HTA on CD?Please use the form on the HTA website (www.hta.ac.uk/htacd.htm). Or contact Direct Mail Works (see contact details above) by email, post, fax or phone. HTA on CD is currently free of charge worldwide.The website also provides information about the HTA Programme and lists the membership of the various committees. HTA NIHR Health Technology Assessment ProgrammeT he Health Technology Assessment (HTA) Programme, part of the National Institute for Health Research (NIHR), was set up in 1993. It produces high-quality research information on the effectiveness, costs and broader impact of health technologies for those who use, manage and provide care in the NHS. 'Health technologies' are broadly defined as all interventions used to promote health, prevent and treat disease, and improve rehabilitation and long-term care. The research findings from the HTA Programme directly influence decision-making bodies such as the National Institute for Health and Clinical Excellence (NICE) and the National Screening Committee (NSC). HTA findings also help to improve the quality of clinical practice in the NHS indirectly in that they form a key component of the 'National Knowledge Service'. The HTA Programme is needs-led in that it fills gaps in the evidence needed by the NHS. There are three routes to the start of projects. First is the commissioned route. Suggestions for research are actively sought from people working in the NHS, the public and consumer groups and professional bodies such as royal colleges and NHS trusts. These sugges...

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“…There are numerous solutions that have been presented in the literature in order to enhance the antimicrobial properties of polymeric materials e.g. antibiotics or silver containing coatings and composites [9][10][11][12][13]. Compared to some antibiotics, nano-silver coatings have shown superior antimicrobial properties.…”

mentioning

confidence: 99%

The influence of Ag+, Zn2+ and Cu2+ exchanged zeolite on antimicrobial and long term in vitro stability of medical grade polyether polyurethane

Kaali¹,

Pérez-Madrignal²,

Strömberg³

et al. 2011

Express Polym. Lett.

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This study aims to investigate the limitations and applicability of different ion exchanged zeolites as antimicrobial additive in thermoplastic polyether type polyurethanes. These composites were designed to improve the health quality of hospitalized patients by expressing both biocompatibility and relevant antimicrobial activity. The zeolites were exchanged with silver, copper and zinc ions and single, binary and ternary ion-exchanged zeolite-polyurethane composites were prepared. The antimicrobial activity and the resistance of the composites against the human environment play vital role in the applicability of the materials as a medical device therefore these properties were investigated. The antimicrobial test were performed on Methicillin-resistant Staphylococcus aureus, Pseudomonas aeruginosa and Candida tropicalis. The tests showed that the efficiency of the silver ions is superior to the other single ionic systems. Besides, the binary and ternary ion-exchanged samples had similar antimicrobial efficiency regardless the type of the ions in the zeolite. The biocompatibility tests were carried out in-vitro in artificial body fluids for a period of 12 weeks. As a result of the invitro test, degradation of the composites were observed and the structural changes of the materials were detected and described by Scanning Electron Microscopy, Contact Angle measurements and Attenuated Total Reflection Fourier Transform Infrared Spectroscopy

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Antibiotic-Impregnated Catheters Associated With Significant Decrease in Nosocomial and Multidrug-Resistant Bacteremias in Critically Ill Patients

Cited by 75 publications

References 28 publications

Strategies to Prevent Central Line–Associated Bloodstream Infections in Acute Care Hospitals

Strategies to Prevent Central Line–Associated Bloodstream Infections in Acute Care Hospitals

The clinical effectiveness and cost-effectiveness of central venous catheters treated with anti-infective agents in preventing bloodstream infections: a systematic review and economic evaluation

The influence of Ag+, Zn2+ and Cu2+ exchanged zeolite on antimicrobial and long term in vitro stability of medical grade polyether polyurethane

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