Antibiotic activity of marine microorganisms

Baam, Roshan B.; Gandhi, N. M.; Freitas, Yvonne M.

doi:10.1007/bf01612663

Cited by 22 publications

(9 citation statements)

References 21 publications

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“…Pseudoalteromonas luteoviolacea, Pseudoalteromonas tunicata and Pseudoalteromonas aurantia isolated from sponges and algae, which inhibited the growth of other bacteria in the marine environment . In this study, the most active isolates were closely related to Bacillus species and moreover, showed a broader spectrum of activity, which agrees with the findings of Baam et al (1966).…”

Section: Discussionsupporting

confidence: 90%

Antifouling activity of symbiotic bacteria from sponge Aplysina gerardogreeni

Águila-Ramírez

Hernández-Guerrero

González‐Acosta

et al. 2014

International Biodeterioration & Biodegradation

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Section: Discussionsupporting

confidence: 90%

Antifouling activity of symbiotic bacteria from sponge Aplysina gerardogreeni

Águila-Ramírez

Hernández-Guerrero

González‐Acosta

et al. 2014

International Biodeterioration & Biodegradation

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“…DISCUSSION Marine bacteria showing antibacterial (3,13,18,20,25), antiviral (12,27,30), and antiyeast (6, 31) activities have been described for more than 20 years. However, at present, the literature concerning the isolation and characterization of the inhibitory compounds is scarce.…”

Section: Resultsmentioning

confidence: 99%

“…Antibiotic production by marine bacteria has been documented for a long time (3,6,8,13,18,20,25). However, there is a paucity of information dealing with the isolation and purification of the active inhibitory substances.…”

mentioning

confidence: 99%

Purification and characterization of an antibacterial substance produced by a marine Alteromonas species

Barja

Lemos

Toranzo

1989

Antimicrob Agents Chemother

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An extracellular inhibitory substance produced by the marine Alteromonas strain P-31 (NCMB 2144) was isolated and purified. The inhibitor was a macromolecule with a molecular weight of 90,000 estimated by Sephadex G-100 chromatography and sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The inhibitory activity was antagonized by proteinase K and I-amylase and inactivated by heating at 80°C for 30 min. The purified substance exhibited two typical absorption bands in the infrared spectrum at 1,650 and 1,075 cm-l, corresponding to peptide linkages and carbohydrate residues, respectively. These findings allowed us to characterize the antimicrobial compound as a thermolabile glycoprotein. The substance exhibited a broad inhibitory spectrum, being active against clinical and environmental isolates from related and nonrelated taxonomical bacterial groups as well as against the producer strain and other similar marine bacterial strains. The inhibitory glycoprotein did not display cytotoxicity toward mammalian and fish cell lines.

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“…The production of antibiotics by marine bacteria is well documented [1][2][3][4][5][6][7][8][9] although, until now, no studies on marine photosynthetic bacteria have been performed despite their widespread occurrence [10]. A current and widely applicable definition of an antibiotic is a compound which in small quantities can inhibit the growth of, or kill, microbes.…”

Section: Introductionmentioning

confidence: 99%

Antibiotic production by the marine photosynthetic bacterium Chromatium purpuratum NKPB 031704: localization of activity to the chromatophores

Burgess

1991

FEMS Microbiology Letters

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Over 200 strains of marine purple photosynthetic bacteria were isolated. Two strains showed antibiotic activity towards Saccharomyces cerevisiae and were tentatively identified as Chromatium purpuratum. Crude antibiotic, prepared by solvent extraction, showed a broad antimicrobial spectrum. The highest activity was found in the chromatophore fraction. Chromatographic separation of purified light harvesting complex from one strain, NKPB 031704, showed the presence of two separate pigmented compounds which were responsible for antimicrobial activity. Our findings reveal the unexpected ability of photosynthetic bacteria to produce broad spectrum antibiotics. In addition, this is the first example of intracellular localization of antibiotic activity in a marine bacterium.

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Antibiotic activity of marine microorganisms

Cited by 22 publications

References 21 publications

Antifouling activity of symbiotic bacteria from sponge Aplysina gerardogreeni

Antifouling activity of symbiotic bacteria from sponge Aplysina gerardogreeni

Purification and characterization of an antibacterial substance produced by a marine Alteromonas species

Antibiotic production by the marine photosynthetic bacterium Chromatium purpuratum NKPB 031704: localization of activity to the chromatophores

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