Antibacterial Studies and Effect of Poloxamer on Gold Nanoparticles by Zingiber Officinale Extracted Green Synthesis

Abstract

Poloxamer finds excellent clinical and therapeutic uses for curing of various ailments. The Zin- giber officinale (Z. officinale) is one of the well-known medicinal plants. The poloxamer188 and the rhizome extract of Z. officinale have been used to synthesize the gold nanoparticles (AuNPs) by a green approach. The Z. officinale extract has been used as a reducing agent while the polox- amerl88 has been used as a stabilizing agent. The effect of addition of poloxamer on the controlling the shape and size of the AuNPs has been investigated by transmission electron microscopy (TEM) and dynamic light scattering techniques. The formation of AuNPs has also been confirmed by UV-Visible spectral, energy dispersive X-ray (EDX) and powder X-ray diffraction (XRD) analyses. The anti-bacterial activity of the green synthesized AuNPs has been investigated on the three human pathogens Staphylococcus aureus, Escherichia coli, and Klebsiella pneumonia. The poloxamer188 protected AuNPs inhibit the bacterial growth more effectively than the pure Z. officinale extract and the standard tetracycline (TA).

Synthesis and comparative studies of MnFe2O4 nanoparticles with different natural polymers by sol–gel method: structural, morphological, optical, magnetic, catalytic and biological activities

“…The antimicrobial activity of nanoparticles depends on the size and morphologies of the samples [20,21]. So far limited information is available on the antimicrobial properties of MnFe 2 O 4 NPs.…”

A New Green Catalyst for Synthesis of bis-Macromonomers of Polyethylene Glycol (PEG)

“…The synthesis of these amphiphilic block copolymers and their applications in biomedical field such as in drug delivery has been largely described in the literature [1][2][3][4][5][6][7][8][9][10][11]. Recently, bioadsorbable hydrogels have been made from a block copolymer of PLA and PEG, both having biocompatible and biodegradable nature, and were applied to the development of micelle-like nanoparticles as chemotherapeutic carrier [12][13][14][15][16][17], short interfering RNA delivery system for 1 Laboratoire de Chimie des Polymères, Département de Chimie, FSEA, University of Oran 1 Ahmed Benbella BP N° 1524 El M'Naouar, 31000 Oran, Algeria 2 FSEI University of Abdelhamid Ibn Badis -Mostaganem * amineharrane@yahoo.fr Ó Benachour M., El-Kebir A., Harrane A., Meghabar R., Belbachir M., 2020 heart regeneration [18], vaccine delivery system against hepatitis B [19,20], injectable scaffolds in the tissue engineering [1][2][3], etc.…”

“…The principal method used for the synthesis of dimethacrylated block copolymer PLA-PEG-PLA consists of two steps: the synthesis of di-hydroxyl PLA-PEG-PLA by the polymerization of lactide in the presence of PEG as macro-initiator using organo-metallic catalysts, such as stannous octoate [1,13,[19][20][21][22][23], and esterification reaction by methacryloyl chloride or methacrylic anhydride to produce di-methacrylated copolymers [23][24]. For biomedical applications, traces of metallic catalysts must be absolutely removed from the polymer because of its toxicity.…”

Biological mediated Ag nanoparticles from Barleria longiflora for antimicrobial activity and photocatalytic degradation using methylene blue

“…In addition, an experimental setup can threaten the human health and the environment due to the excessive usage of toxic chemicals and their by-products during the synthesis process [13]. Extraction of nanoparticles from plant leaves naturally makes the process simple, eco-friendly and an efficient method [14][15][16][17]. Hence, it is very essential to focus on alternative techniques, which may lead to the consumption of fewer chemicals and natural sources (plant species), for the synthesis of Ag-NPs [18][19][20].…”