Antibacterial Shoe Insole-Coated CuO-ZnO Nanocomposite Synthesized by the Sol-Gel Technique

Abstract

In this study, CuO-ZnO composite was synthesized via the sol-gel method using oxalic acid to form the medium complex and its applications in antibacterial have been conducted with B. cereus, E. coli, S. aureus, Salmonella, and P. aeruginosa. Then, nanopowder of CuO-ZnO was coated on shoe insoles and their antibacterial effect with S. aureus was tested. The nanocomposite products were characterized by XRD, XPS, SEM, TEM, and UV-Vis. The results showed that the CuO-ZnO composite has the average particle size in a range of 20-50 nm, the point of zero charge of 7.8, and the bandgap of 1.7 eV. XPS result shows the composite structure with Cu2+ in the product. The minimum inhibitory concentration (MIC) of CuO-ZnO nanocomposite was 0.313 mg·mL-1 for S. aureus and Samonella, 0.625 mg·mL-1 for E. coli, and 5 mg·mL-1 for B. cereus and P. aeruginosa. The shoe insoles coated with 0.35 wt.% of CuO-ZnO nanocomposite also had high antibacterial activity against S. aureus, and this antibacterial nanocomposite was implanted durably on the surface of the shoe insoles.

Biogenic Synthesis of CuO, ZnO, and CuO–ZnO Nanoparticles Using Leaf Extracts of Dovyalis caffra and Their Biological Properties

“…On the other hand, the SEM micrograph of CuO nanoparticles in Figure 4 b showed that they are mostly composed of uniform nanoflakes that are aggregated in a repetitive pattern, with interconnected thin flakes similar to other report [ 46 ]. Additionally, the SEM micrograph of ZnO Nps in Figure 4 c shows densely stacked short hexagonal rod-like structures that are randomly distributed similar to earlier report [ 47 , 48 ]. Furthermore, from the obtained TEM images in Figure 5 c, CuO–ZnO shows an array of spherical-shaped particles with a diameter ranging from 20–32 nm, which are somewhat arranged like a short nanorod.…”

Green Synthesis of a CuO–ZnO Nanocomposite for Efficient Photodegradation of Methylene Blue and Reduction of 4-Nitrophenol

“…CuO–ZnO NCs can be fabricated by various methods including precipitation, sol–gel, solvothermal, electrospinning, photodeposition, microwave-assisted, electrochemical, thermal decomposition, and spray pyrolysis . Among these methods, a microwave-assisted method has several benefits in comparison to conventional heating methods, such as fast reactions, uniform particle size distribution, high yield, and highly pure nanomaterials .…”