Antibacterial Sesquiterpene Lactones from Kaunia lasiophthalma

Abstract

Phytochemical study of the species Kaunia lasiophthalma enabled the isolation of three undescribed and three known guaianolide‐type sesquiterpene lactones, and one new benzofuran. The bioguided fractionation methodology was successful in detecting antimicrobial metabolites against Staphylococcus aureus strains and permitted the description of undescribed guaianolide‐type sesquiterpene lactones with substitution patterns matching all those described in the Oxylobinae subtribe.