Antibacterial properties of silver dendrite decorated silicon nanowires

Alhmoud, Hashim; Delalat, Bahman; Cetó, Xavier; Elnathan, Roey; Cavallaro, Alex; Vasilev, Krasimir; Voelcker, Nicolas H.

doi:10.1039/c6ra13734b

Cited by 37 publications

(22 citation statements)

References 53 publications

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“…Surfaces with tailored nanotopography are being investigated as novel cell culture substrate because they can be tuned to improve cell adhesion, modulate immune response and direct stem cells differentiation into targeted lineages . Additionally, careful surface nanoengineering can also help controlling bacterial adhesion and biofilm formation . Nanostructured thin films are therefore entering the biomedical field as novel low‐fouling coatings for implant and devices …”

Section: Why Nanotopography?supporting

confidence: 77%

Questions and Answers on the Wettability of Nano‐Engineered Surfaces

MacGregor

Vasilev

2017

Adv Materials Inter

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Surface roughening has long been used to confer materials remarkable wetting properties, such as super hydrophobicity. When roughness belongs to the microscale, existing models can, to some extent, explain and predict real‐world wetting states. With the advent of nanotechnology, however, a multitude of nano‐engineered materials are being developed and unexpected wetting behaviors have been observed which cannot be described by conventional theories. While it is clear that advanced nanotextured materials are essential to a vast range of ground breaking technologies, the intricate mechanisms governing the wetting of such surfaces—at the limit of validity of continuum theories—also need to be clarified. This review aims at presenting what is known and what remains to be discovered about the wettability of nanoengineered materials. The advantages and uniqueness of nanostructured substrates is highlighted first, with a focus on practical applications benefitting from the distinctive wetting properties of nanorough substrates. Classic wetting theories and their limitations are briefly discussed, before describing with a top down vision, why the wetting of nanostructured substrates differ from that of microtextured surfaces. Recent experimental and theoretical studies which contributed to the progress in this field are considered, before outlining potential future areas of research.

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Section: Why Nanotopography?supporting

confidence: 77%

Questions and Answers on the Wettability of Nano‐Engineered Surfaces

MacGregor

Vasilev

2017

Adv Materials Inter

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“…HFF is a well-accepted cell line to test general cytotoxicity of materials on mammalian cells. 27,28…”

Section: Methodsmentioning

confidence: 99%

Self-assembled cationic amphiphiles as antimicrobial peptides mimics: Role of hydrophobicity, linkage type, and assembly state

Zhang

Algburi

Wang

et al. 2017

Nanomedicine: Nanotechnology, Biology and Medicine

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Inspired by high promise using naturally occurring antimicrobial peptides (AMPs) to treat infections caused by antimicrobial-resistant bacteria, cationic amphiphiles (CAms) were strategically designed as synthetic mimics to overcome associated limitations, including high manufacture cost and low metabolic stability. CAms with facially amphiphilic conformation were expected to demonstrate membrane-lytic properties and thus reduce tendency of resistance development. By systematically tuning the hydrophobicity, CAms with optimized compositions exhibited potent broad-spectrum antimicrobial activity (with minimum inhibitory concentrations in low μg/mL range) as well as negligible hemolytic activity. Electron microscope images revealed the morphological and ultrastructure changes of bacterial membranes induced by CAm treatment and validated their membrane-disrupting mechanism. Additionally, an all-atom molecular dynamics simulation was employed to understand the CAm-membrane interaction on molecular level. This study shows that these CAms can serve as viable scaffolds for designing next generation of AMP mimics as antimicrobial alternatives to combat drug-resistant pathogens.

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“…The synthetic protocols which we developed involve a range of reduction and capping agents (lipids, 2-mercaptosuccinic acid, citrate, polyvinyl-sulphonate, etc. ), including a procedure that benefited from the properties of natural products, such as cacao extract [64,71,[73][74][75][76][77][78]83,86]. These nanoparticles can be immobilised electrostatically or covalently to plasma polymer films containing appropriate surface functionalities ( Figure 5) [70,71,75,79,87].…”

Section: Silver Containing Coatings and Materialsmentioning

confidence: 99%

Nanoengineered Antibacterial Coatings and Materials: A Perspective

Vasilev

2019

Coatings

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This feature article begins by outlining the problem of infection and its implication on healthcare. The initial introductory section is followed by a description of the four distinct classes of antibacterial coatings and materials, i.e., bacteria repealing, contact killing, releasing and responsive, that were developed over the years by our team and others. Specific examples of each individual class of antibacterial materials and a discussion on the pros and cons of each strategy are provided. The article contains a dedicated section focused on silver nanoparticle based coatings and materials, which have attracted tremendous interest from the scientific and medical communities. The article concludes with the author’s view regarding the future of the field.

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Antibacterial properties of silver dendrite decorated silicon nanowires

Abstract: Silicon nanowires fabricated through Ag-assisted chemical etching were found to be effective bacterial-traps with strong antibacterial properties resulting from Ag-nanoclusters.

Cited by 37 publications

References 53 publications

Questions and Answers on the Wettability of Nano‐Engineered Surfaces

Questions and Answers on the Wettability of Nano‐Engineered Surfaces

Self-assembled cationic amphiphiles as antimicrobial peptides mimics: Role of hydrophobicity, linkage type, and assembly state

Nanoengineered Antibacterial Coatings and Materials: A Perspective

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