Antibacterial Properties of Functionalized Gold Nanoparticles and Their Application in Oral Biology

Abstract

As bacterial resistance is becoming increasingly serious, the development of antibacterial nanomaterials is an effective method of solving this problem. Gold nanoparticles have good stability and excellent biocompatibility and are easily modified, and their antibacterial properties can be enhanced by changing their structure and size or adding ingredients. Gold nanoparticles are also excellent drug carriers that can improve the antibacterial effects of loaded antibacterial drugs. After being modified and combined with other antibacterial drugs, gold nanoparticles can also play a better antibacterial role for effective antibacterial strategies against some resistant bacteria. Gold nanoparticles have photothermal effects, and modified gold nanoparticles can be a good medium for photothermal treatments to kill bacteria. By adding functionally modified gold nanoparticles, many materials can obtain much needed antibacterial properties. Gold nanoparticles can also be combined with cations, low-temperature plasma, various surface ligands, and other potential antibacterial agents. In short, the antibacterial characteristics of functionalized gold nanoparticles demonstrate that they have considerable practical application value and provide more ideas to solve antibacterial problems. At the same time, the application of gold nanoparticles in oral biology is also increasing.

Synthesis of Silver and Gold Nanoparticles in Sodium Alginate Matrix Enriched with Graphene Oxide and Investigation of Properties of the Obtained Thin Films

“…Thus, smoothing the edges leads to the deactivation of the antimicrobial action [58]. The zone of growth inhibition for Escherichia coli when exposed to nanogold may also result from the impairment of proteins, lipids and nucleic acids present in bacterial cell membranes [59,60]. The absence of inhibition zones for microbial growth after 48 h of incubation in the case of nanogold is not a result that excludes its antimicrobial activity.…”

“…One of the described ways of the influence of nanometals on microorganisms is the ion release-the lower activity of nanogold can be caused by the slower ion release compared to nanosilver [61][62][63]. It seems reasonable to continue microbiological studies over longer incubation periods or increased nanogold concentrations [60].…”

Antibacterial and Anti-Inflammatory Coating Materials for Orthopedic Implants: A Review

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Immunomodulatory Function of Polyvinylpyrrolidone (PVP)-Functionalized Gold Nanoparticles in Vibrio-Stimulated Sea Urchin Immune Cells

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