Antibacterial properties and cytocompatibility of tantalum oxide coatings with different silver content

Abstract

Tantalum (Ta) oxides and their coatings have been proved to increase their applications in the biomedical fields by improving osseointegration and wear resistance. In this study, Ta oxide coatings containing different proportions of Ag are deposited on SS304 materials. A twin-gun magnetron sputtering system is used to deposit the tantalum oxide-Ag coating. In this study, Staphylococcus aureus, which exhibits physiological commensalism on the human skin, nares, and mucosal and oral areas, is chosen as the model for in vitro antibacterial analyses via a fluorescence staining method using Syto9. The cytocompatibility and adhesive morphology of human skin fibroblast cells (CCD-966SK) on the coatings are also determined by using the microculture tetrazolium assay. This study shows that Ta2O5 and Ta2O5-Ag coatings with 12.5 at. % of Ag exhibit improved antibacterial effects against S. aureus and have good skin fibroblast cell cellular biocompatibility.

Potential antibacterial mechanism of silver nanoparticles and the optimization of orthopedic implants by advanced modification technologies

“…Furthermore, AgNPs incorporated on the implant surface by sputtering can increase water contact angle and improve hydrophobicity of the substrate surface. 113 It was found that with a decreased sputtering time, surface roughness and wettability were higher. An increasing roughness value is well known to be associated with increased osteoblast adhesion.…”

Preparation, Microstructure, Mechanical Properties and Biocompatibility of Ta-Coated 3Y-TZP Ceramic Deposited by a Plasma Surface Alloying Technique

“…Figure 4b shows the elemental diffusion of Ta, Zr and O in the diffusion zone, respectively. Here, the non-steady diffusion was caused by bombardment of argon ions during the fabrication process of Ta coating, so Fick's second law was employed to evaluate the non-equilibrium diffusion between the Ta coating and the substrate [17,24]: (1) where D, t and x are the diffusion coefficient, time and location, respectively. The concentration of any diffusing location, C, could be got as:…”

Microstructure, Wettability, Corrosion Resistance and Antibacterial Property of Cu-MTa2O5 Multilayer Composite Coatings with Different Cu Incorporation Contents

“…In the high-resolution spectrum of Ta 4f (Figure 8b), two peaks located at the binding energy position of 25.8 eV and 27.7 eV correspond to the characteristic peaks of Ta 4f 7/2 and Ta 4f 5/2 , respectively, indicating that the chemical state of Ta on the surface of C3 sample is Ta 2 O 5 [17]. energy position of 531.3 eV, 530.2 eV and 529.8 eV could be attributed to Ta2O5, CuO and Cu2O, respectively [54][55][56]. These results show that the chemical state of the Ta element in Cu-MTa2O5 composite coating is Ta2O5, while both CuO and Cu2O existed as state Cu elements.…”

“…In high-resolution XPS spectrum of O 1s (Figure 8f), three deconvolution peaks at binding energy position of 531.3 eV, 530.2 eV and 529.8 eV could be attributed to Ta 2 O 5 , CuO and Cu 2 O, respectively [54][55][56]. These results show that the chemical state of the Ta element in Cu-MTa 2 O 5 composite coating is Ta 2 O 5 , while both CuO and Cu 2 O existed as state Cu elements.…”