Antibacterial Potential of Clonally Propagated Prunella vulgaris L. under in vitro Conditions

Çetin, Burcu; Kalyoncu, Fatih

doi:10.9734/jamps/2018/43626

Cited by 1 publication

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References 9 publications

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“…In addition, the 2020 edition of Chinese Pharmacopoeia stipulated that rosmarinic acid was used as the content determination index of its quality control. Modern pharmacological studies have shown that it has extensive pharmacological activities, and has certain pharmacological effects on anti-tumor, antibacterial and antiviral, anti-inflammatory and immune regulation, antihypertensive, hypoglycemic, hypolipidemic, antioxidant and free radical scavenging, liver protection and so on ( Ryu et al, 1992 ; Fang et al, 2005a ; Sárosi and Bernath, 2008 ; Kim, 2012 ; Zhang et al, 2014 ; Huang et al, 2015 ; Raafat et al, 2016 ; Çetin and Kalyoncu, 2018 ; Ahmad et al, 2020 ; Zhang et al, 2020 ). More than any of these, its excellent quality and remarkable curative effect have also been highlighted in clinical application.…”

Section: Introductionmentioning

confidence: 99%

Prunella vulgaris L. – A Review of its Ethnopharmacology, Phytochemistry, Quality Control and Pharmacological Effects

2022

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Prunella vulgaris L. (PVL) is dried fruit spike of Lamiacea plant Prunella vulgaris L., which is a perennial herb with medicinal and edible homology used for thousands of years. PVL is bitter, acrid, cold, and belongs to the liver and gallbladder meridians. It clears the liver and dissipate fire, improve vision, disperse swelling, and has satisfactory clinical therapeutic effects on many diseases such as photophobia, dizziness, scrofula, goiter, breast cancer. The collection of information and data related to PVL comes from literatures retrieved and collated from various online scientific databases (such as CNKI, VIP, PubMed, Web of Science, Research Gate, Science Database), ancient books of traditional chinese medicine (Encyclopedia of Traditional Chinese Medicine, Classics of Traditional Chinese Medicine, Dictionary of Traditional Chinese Medicine), and Doctoral and Master’s Dissertations. Currently, the major chemical constituents isolated and identified from PVL are triterpenoids, steroids, flavonoids, phenylpropanoids, organic acids, volatile oils and polysaccharides. Modern pharmacological studies have shown that PVL has a wide range of pharmacological activities, including anti-inflammatory, anti-tumor, antibacterial and antiviral effects, as well as immune regulation, antihypertensive, hypoglycemic, lipid-lowering, antioxidant, free radical scavenging, liver protection, sedative and hypnotic effects. This paper reviewes the botany, ethnopharmacology, traditional application, phytochemistry, analytical methods, quality control, pharmacological effects of PVL. It can be used not only as medicine, but also gradually integrated into the “medicine and food homology” and “Chinese medicine health” boom. More importantly, it has great potential for drug resources development. This paper deeply discusses the shortcomings of current PVL research, and proposes corresponding solutions, in order to find a breakthrough point for PVL research in the future. At the same time, it is necessary to further strengthen the research on its medicinal chemistry, mechanism of action and clinical application efficacy in the future, and strive to extract, purify and synthesize effective components with high efficiency and low toxicity, so as to improve the safety and rationality of clinical medication.

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Section: Introductionmentioning

confidence: 99%

Prunella vulgaris L. – A Review of its Ethnopharmacology, Phytochemistry, Quality Control and Pharmacological Effects

2022

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Antibacterial Potential of Clonally Propagated Prunella vulgaris L. under in vitro Conditions

Abstract: Aims:The study aims to determine the antibacterial efficacy of Prunella vulgaris plant produced by micropropagation method.

Cited by 1 publication

References 9 publications

Prunella vulgaris L. – A Review of its Ethnopharmacology, Phytochemistry, Quality Control and Pharmacological Effects

Prunella vulgaris L. – A Review of its Ethnopharmacology, Phytochemistry, Quality Control and Pharmacological Effects

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