Antibacterial efficacy of triclosan-incorporated polymers

Effect of chemical structure of thermoplastics on antibacterial activity and physical diffusion of triclosan doped in vinyl thermoplastics and their composites with CaCO3

“…Among the thermoplastics used, it was observed that at the lowest triclosan concentration (5000 ppm), the inhibition zone for PS was the smallest. Work by Kalyon et al 17 suggested that the triclosan-filled PS could inhibit the bacteria growth (E.coli and B.thuringiensis) only for a short period of time because triclosan could not effectively diffuse through the PS to kill the bacteria. In this work, three possible explanations for the differences in inhibition zones for all thermoplastics used were proposed, these including (i) rigidities of the thermoplastics, (ii) abilities to crystallize, (iii) free volume or molecular density.…”

“…They found that the relevant release rate of triclosan from the drawn specimens was lower than the nonstretched samples due to the molecular orientation developed during the drawing process. Kalyon et al 17 assessed the antibacterial efficacy of triclosanincorporated PS disks against Escherichia coli and Bacillus thuringiensis. The results suggested that triclosan-filled PS inhibited the bacteria growth for some periods, after which bacteria growth resumed and the bulk of the triclosan in the polymer was not available for interaction with bacteria.…”

“…[7][8][9][10][11][12][13][14][15][16][17] None of these studies have addressed relationship between triclosan and chemical structure of thermoplastics on the antibacterial activities. Besides, In practical point of view, fillers (reinforcing and extending fillers) are usually required for promoting the physical and mechanical properties, for stabilizing the chemical structures, and for reducing the product costs.…”

Contact‐Active Antimicrobial Coatings Derived from Aqueous Suspensions

“…Increasing hygiene standards and the threat of infectious disease demand materials with surfaces that inhibit the survival and proliferation of microbes. Most commercial materials of this type rely on impregnation with biocides, such as silver ions, [1] quaternary ammonium compounds, [2] triclosan, [3] chlorohexidine, [4] chlorine, [5] tributyltin, [6] and diverse antibiotics. [7] Although effective, the ongoing release of biocides contaminates the environment [8,9] and promotes the development of resistant microbial strains, which is one of the most important problems facing modern medicine.…”

Evaluation of Microbial Contamination in Frequently Used Fomites in Kuwait

“…5 Other suggested techniques to decrease bacterial contaminations include use of antimicrobial additive materials and surface coatings to fabricate telephones, door knobs, fabrics and various building materials. [20][21][22] The current study was conducted to determine the type of microbial cross-contamination on different surfaces and locations in Kuwait. These include fitness club equipment, gas station, home, supermarket, and microbiology lab at hospital.…”