Antibacterial effects of supernatant of lactic acid bacteria isolated from different Dough's in Gorgan city in north of Iran

Rashti, Zeinab; Koohsari, Hadi

doi:10.15761/ifnm.1000129

Cited by 10 publications

(5 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Interestingly, adiponectin injection improved intestinal permeability evidenced by decreasing serum LPS and enhancing colonic expressions of tight junctions in mice. The high level of serum LPS is considered to be the consequence of the increased intestinal permeability [ 45 ]. Thus, the in vivo results suggested a beneficial role of adiponectin in barrier integrity, which was further demonstrated in Caco-2 cells that adiponectin alleviated DSS-induced the decreased TEER and increased FD-4 flux.…”

Section: Discussionmentioning

confidence: 99%

RETRACTED ARTICLE: Adiponectin administration alleviates DSS-induced colonic inflammation in Caco-2 cells and mice

Zhao

Liu²,

Tan

et al. 2018

Inflamm. Res.

View full text Add to dashboard Cite

BackgroundAdiponectin, a protein hormone produced by adipose tissues, exhibits anti-inflammatory functions in various models. This study was investigated the effects of adiponectin on dextran sodium sulfate (DSS)-colonic injury, inflammation, apoptosis, and intestinal barrier dysfunction in Caco-2 cell and mice.Materials and methodsThe results showed that DSS caused inflammatory response and intestinal barrier dysfunction in vitro and in vivo. Adiponectin injection alleviated colonic injury and rectal bleeding in mice. Meanwhile, adiponectin downregulated colonic IL-1β and TNF-α expressions and regulated apoptosis relative genes to attenuate DSS-induced colonic inflammation and apoptosis. Adiponectin markedly reduced serum lipopolysaccharide concentration, a biomarker for intestinal integrity, and enhanced colonic expression of tight junctions (ZO-1 and occludin). The in vitro data further demonstrated that adiponectin alleviated DSS-induced proinflammatory cytokines production and the increased permeability in Caco-2 cells.ConclusionAdiponectin plays a beneficial role in DSS-induced inflammation via alleviating apoptosis and improving intestinal barrier integrity.

show abstract

Section: Discussionmentioning

confidence: 99%

RETRACTED ARTICLE: Adiponectin administration alleviates DSS-induced colonic inflammation in Caco-2 cells and mice

Zhao

Liu²,

Tan

et al. 2018

Inflamm. Res.

View full text Add to dashboard Cite

show abstract

“…Excess generation of free redical species and oxidative stress have been suggested to involve in the development of acute respiratory failure [ 13 , 14 ]. To maintain cellular oxidative balance, antioxidant enzymes (i.e.…”

Section: Discussionmentioning

confidence: 99%

Indirubin improves antioxidant and anti-inflammatory functions in lipopolysaccharide-challenged mice

2017

Oncotarget

View full text Add to dashboard Cite

Indirubin, a traditional Chinese medicine formulation from the Muricidae family, has been reported to exhibit abroad anti-cancer and anti-inflammation activities and mediate nuclear factor-κB (NF-κB) signal. Thus, this study aimed to investigate the protective effects of indirubin on LPS-induced acute lung injury and the potential mechanism in mice. The results showed that LPS treatment caused oxidative stress and inflammation in mice. Indirubin alleviated LPS-caused oxidative stress and inflammation via reducing MDA abundance and IL-1β and TNF-α expressions in mice. Meanwhile, indirubin improved lung NO production and inhibited NF-κB activation caused by LPS exposure. In conclusion, indirubin alleviated LPS-induced acute lung injury via improving antioxidant and anti-inflammatory functions, which might be associated with the NO and NF-κB signals.

show abstract

“…Phosphorylation of IκBs is associated with its degradation and NF-κB activation (Yan and Polk, 1999). Compelling evidence suggests that NF-κB is activated in IBD and other inflammatory diseases (Cheon et al, 2006;Vinod and Guruvayoorappan, 2014;Rashti and Koohsari, 2015). Thus, inhibition of the NF-κB signaling pathway has been considered to be a potential target for IBD therapy.…”

Section: Discussionmentioning

confidence: 99%

Hydrogen sulfide from a NaHS source attenuates dextran sulfate sodium (DSS)-induced inflammation via inhibiting nuclear factor-κB

Chen

Liu

2016

J. Zhejiang Univ. Sci. B

View full text Add to dashboard Cite

This study investigated the alleviating effects of hydrogen sulfide (H2S), derived from sodium hydrosulfide (NaHS), on inflammation induced by dextran sulfate sodium (DSS) in both in vivo and in vitro models. We found that NaHS injection markedly decreased rectal bleeding, diarrhea, and histological injury in DSS-challenged mice. NaHS (20 μmol/L) reversed DSS-induced inhibition in cell viability in Caco-2 cells and alleviated pro-inflammation cytokine expression in vivo and in vitro, indicating an anti-inflammatory function for H2S. It was also found that H2S may regulate cytokine expression by inhibiting the nuclear factor-κB (NF-κB) signaling pathway. In conclusion, our results demonstrated that H2S alleviated DSS-induced inflammation in vivo and in vitro and that the signal mechanism might be associated with the NF-κB signaling pathway.

show abstract

Antibacterial effects of supernatant of lactic acid bacteria isolated from different Dough's in Gorgan city in north of Iran

Cited by 10 publications

References 3 publications

RETRACTED ARTICLE: Adiponectin administration alleviates DSS-induced colonic inflammation in Caco-2 cells and mice

RETRACTED ARTICLE: Adiponectin administration alleviates DSS-induced colonic inflammation in Caco-2 cells and mice

Indirubin improves antioxidant and anti-inflammatory functions in lipopolysaccharide-challenged mice

Hydrogen sulfide from a NaHS source attenuates dextran sulfate sodium (DSS)-induced inflammation via inhibiting nuclear factor-κB

Contact Info

Product

Resources

About