Antibacterial effect of a gingival patch containing nano-emulsion of red dragon fruit peel extract on Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, and Fusobacterium nucleatum assessed in vitro

Diyatri, Indeswati; Juliastuti, Wisnu Setyari; Ridwan, Rini Devijanti; Ananda, Ghinalya Chalbi; Waskita, Fuad Adhi; Juliana, Nita Vania; Khansa, Shafa Putri; Pratiwi, Reinaya Tifa; Putri, Cindy Ramadhan

doi:10.1016/j.jobcr.2023.03.011

Cited by 3 publications

(5 citation statements)

References 27 publications

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“…by-products. Diyatri, I. et al [8] Antibacterial effect of a gingival patch containing nano-emulsion of red dragon fruit peel extract on Porphyromonas gingivalis,Aggregatibacter actinomycetemcomitans, and Fusobacterium nucleatum assessed in vitro Leong, H. Y., Ooi, C. W., Law, C. L., Julkifle, A. L., Ling, T. C., & Show, P. L. [9] Application of liquid biphasic flotation for betacyanins extraction from peel and flesh of Hylocereus polyrhizus and antioxidant activity evaluation. Shad, Z., Mirhosseini, H., Hussin, A. S. M., Forghani, B., Motshakeri, M., & Manap, M. Y.…”

Section: A Resultados Bibliométricos De La Revisión Sistemáticamentioning

confidence: 98%

“…Método de extracción Producto extraído de valor agregado [8] Difusión Flavonoides [31] Solución de etanol Clorofila -Antocianina [35] Enfoque de activación química Catalizador libre [28] Método pHpzc, (FTIR), (SEM/EDS). Polvo de pitahaya [29] Método DPPH, Método ABTS Flavonoides [15] Solución de etanol Antocianina [21] Extracción acuosa Flavonoides [30] Método LC-MS y GC-MS Fenoles y Flavonoides [23] Método de adsorción Biosorbentes naturales modificados químicamente [12] Método ABTS, DPPH Flavonoides y polifenoles [39] Ultrasonido Polifenoles [34] Coagulación y Floculación Mucílago [16] Análisis por HPLC Ácido gálico y ferúlico [27] Extracción ácida en caliente a pH 3,5 Pectina [14] Solución alcoholica Betacianina [32] Microondas Alto metoxil-pectina [26] Extracción asistida por ultrasonidos.…”

Section: Fuenteunclassified

“…También es importante mencionar que se puede utilizar para la eliminación de tintes de aguas residuales en industria textil [18]. Finalmente, en la Tabla VII se muestran las oportunidades de uso en la industria farmacéutica, para el cual la cáscara indica una alta presencia de terpenoides, compuestos fenólicos, flavonoides, y vitaminas, estos le dan un alto nivel de actividad antibacteriana y anticancerígena, contribuyendo a la propuesta como parche gingival mucoadhesivo para aprovechar esta propiedad antibacteriana, extraídos por ensayos in vitro [8]. Sumado a ello, buscan detectar posibles actividades apoptóticas de extractos de cáscara y pulpa de Hylocereus undatus en líneas celulares de cáncer MCF-7 [30].…”

Section: Fuenteunclassified

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Aprovechamiento de la cáscara de Pitahaya. Una Revisión Sistemática de la Literatura

Chávez Romero,

Nicolás Saldaña,

Paz Reyes

et al. 2023

Proceedings of the 3rd LACCEI International Multiconference on Entrepreneurship, Innovation and Regional Development (LEIRD 202

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This systematic review of the literature shows the various research advances, perspectives and current trends regarding the shell of the "dragon fruit", and its possible applications for the generation of products with greater added value, which have sustainable production processes. production. Through the use of the PICO and PRISMA methodology, 39 articles out of a total of 169 were reviewed, with exclusions of keywords, age, titles and abstracts. The results show that among the main compounds, polyphenols, flavonoids, pectins, betacyanins have been found, which demonstrate that the peel is highly usable for various applications. There is a clear trend for the use of highly sustainable extraction techniques (ultrasound and microwave), trying to reduce the use of traditional methods in which organic solvents are used. This diversity of products from the Pitahaya peel are highly promising within the food, chemical and pharmaceutical sectors, having a clear strategy to promote the circular economy in these sectors. Finally, the findings obtained support the feasibility of using Pitahaya peel for various applications, which can generate a positive socioeconomic impact.

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Section: A Resultados Bibliométricos De La Revisión Sistemáticamentioning

confidence: 98%

Section: Fuenteunclassified

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Aprovechamiento de la cáscara de Pitahaya. Una Revisión Sistemática de la Literatura

Chávez Romero,

Nicolás Saldaña,

Paz Reyes

et al. 2023

Proceedings of the 3rd LACCEI International Multiconference on Entrepreneurship, Innovation and Regional Development (LEIRD 202

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show abstract

“…In a study on the inhibition of bacteria that cause periodontitis, gingival patch mucoadhesion containing red dragon fruit peel extract (GP-RDFPE) inhibited Porphyromonas gingivalis, Fusobacterium nucleatum , and Aggregatibacter actinomycetemcomitans [ 19 ] . The inhibitory effects on Porphyromonas gingivalis, Fusobacterium nucleatum, and Aggregatibacter actinomycetemcomitans were significant at an RDFPE concentration of 6.25%, not at an RDFPE concentration of 3.125%.…”

Section: Discussionmentioning

confidence: 99%

“…RDFPE at concentrations of 3.125% and 6.25% inhibited Porphyromonas gingivalis, Fusobacterium nucleatum, and Aggregatibacter actinomycetemcomitans , respectively. An RDFPE concentration of 6.25% is considered the MIC, and an RDFPE concentration of 12.5% is the MBC [ 19 ]. Topical cream obtained from Hylocereus polyrhizus extract has been reported to be effective in wound healing [ 20 ].…”

Section: Discussionmentioning

confidence: 99%

Antimicrobial and Antibiofilm Effects of Silver-Copper Nanoparticles Obtained by Green Synthesis Against Streptococcus mutans

Sarıtaş,

Yiğit,

Karacalı Tunç

et al. 2024

Cureus

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Introduction : Oral diseases affect billions worldwide, with dental caries being a significant concern. Silver-copper nanoparticles (Ag-Cu NPs) synthesized from pitaya plant extract offer a potential solution due to their antimicrobial properties. This study aimed to evaluate the inhibitory effects of Ag-Cu NPs on Streptococcus mutans ( S. mutans ), a major contributor to dental caries. Methodology: Ag-Cu NPs were synthesized using a green chemical method and characterized using a scanning electron microscope (SEM), ultraviolet-visible (U-vis) spectrophotometer, and Fourier Transform Infrared Spectroscopy (FT-IR). The minimum inhibitory concentration (MIC) against S. mutans was determined using the broth microdilution method, while the antibiofilm effect was assessed by the crystal violet method. Results: The synthesized Ag-Cu NPs demonstrated antimicrobial activity with an MIC of 128 µg/ml, significantly inhibiting S. mutans biofilm formation by up to 94% at a concentration of 256 µg/ml. Characterization studies confirmed the successful synthesis of Ag-Cu NPs with spherical morphology. Conclusions: These findings highlight the potential of Ag-Cu NPs as a novel approach for combating dental caries by targeting S. mutans biofilms. Further research is warranted to explore their safety and efficacy in clinical settings.

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Ethanolic extract of red dragon fruit inhibits growth of mosquito larvae

Susanti,

Milyunier,

Nufus

et al. 2023

Healthc Low-resour S

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Controlling the vector by eradicating mosquito larvae is frequently done by spreading Abate powder containing 1% Temephos as a larvicide agent. However, the use of Abate powder will possibly increase pesticide residue contamination in the water. This study aimed to explore the potential use of ethanolic extract from red dragon fruit skin to kill mosquito larvae. An experimental laboratory study was performed to examine the larvicidal activity of ethanolic extract from red dragon fruit skin. Maceration method was used to extract active compounds from the fruit skin. Subsequently, the viscous extract was formulated using the wet granulation method to obtain powder form. The larvicide test was done by comparing the lethal concentration (LC50) of mosquito larvae after treatment using the extract and the reference larvicide agent, 1% Temephos Abate. The treatment groups consisted of four different extract concentrations of 1%, 2%, 3%, and 4%. The LC50 of each treatment groups was then calculated against the negative control group. Phytochemical screening showed that the ethanol extract of red dragon fruit skin contains alkaloids, flavonoids, saponins, triterpenoids, and tannins. The larvicide test on Aedes aegypti mosquito larvae showed that the extract treatment hardly killed the Aedes aegypti mosquito larvae. However, on Culex mosquito larvae, the ethanolic extract of red dragon fruit skin was able to kill mosquito larvae, with LC50 value of of 19.06%. The ethanolic extract of red dragon fruit skin was effective on killing the Culex mosquito larvae but not the Aedes aegypti mosquito larvae.

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Antibacterial effect of a gingival patch containing nano-emulsion of red dragon fruit peel extract on Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, and Fusobacterium nucleatum assessed in vitro

Cited by 3 publications

References 27 publications

Aprovechamiento de la cáscara de Pitahaya. Una Revisión Sistemática de la Literatura

Aprovechamiento de la cáscara de Pitahaya. Una Revisión Sistemática de la Literatura

Antimicrobial and Antibiofilm Effects of Silver-Copper Nanoparticles Obtained by Green Synthesis Against Streptococcus mutans

Ethanolic extract of red dragon fruit inhibits growth of mosquito larvae

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