Antibacterial copper(II) complexes of 1,1′‐symmetric ferrocene‐derived Schiff‐base ligands: studies of the effect of anions on their antibacterial properties

Abstract

Symmetrically substituted 1,1'-dimethylferrocene-derived pyrazine, pyridine and thiazole Schiffbase ligands and their copper(II) complexes have been prepared. The effect of anions on the antibacterial activity of these synthesized metal(II) complexes has been determined.

Synthesis, physical and antimicrobial studies of ferrocenyl-N-(pyridinylmethylene)anilines and ferrocenyl-N-(pyridinylmethyl)anilines

“…Chem., 2016, 69, 51-66, <http://journals.sabinet.co.za/sajchem/>. reviewed by P. Barbaro et al 43 and A. Fihri et al 44 Potential uses of ferrocenylpyridines Schiff bases includes synthesis of materials for usage in electrochemical sensors, 45 homogenous catalysis, 46 cytotoxic agents, 16 antimicrobial compounds, [47][48][49] antiparasitic, 50 liquid crystals, 51 non-linear optical materials, 52 luminescent systems, 53 as well as coordination of a variety of metal centres to yield novel bimetallic complexes with fascinating architectures, 54,55 organometallic polymers 56 and conducting polymers. 57 In view of the aforementioned potential applications of ferrocenylpyridines and ferrocene derived Schiff bases, we have prepared a series of novel mono-substituted ferrocenyl-N-(pyridinylmethylene)anilines Schiff bases and their corresponding ferrocenyl-N-(pyridinylmethyl)anilines secondary amines.…”

Metal-based new sulfonamides: Design, synthesis, antibacterial, antifungal, and cytotoxic properties

“…The complexes (4)-(6) exhibited moderate activity (51-75%) against fungal strain (a) while (2) and (6)- (11) showed moderate activity against (b). Similarly, the complexes (2)- (4), (10) and (11) displayed moderate (51-75%) activity against bacterial strain (c), (7), (10), and (12) against (d), (2) and (5) against (e) and (4), (8), and (12) against (f) fungal strain. All other complexes were inactive or showed weak activity (<50%).…”

“…A parti cular interest in Schiff bases containing specifically oxygen and nitrogen donor atoms and their metal com plexes speedily arose due to their inhibiting properties towards the growth of tumours [4][5][6][7] . The imine bond in Schiff bases plays role in coordination with the metals as well as acting as highly bioactive site [8][9][10][11][12][13][14] . Keeping in view all such aspects, we report in this paper the synthesis of three chlorosubstituted salicylaldehyde derived Schiff base sulfonamides, 4 [ 15,16 .…”

Structure and biological properties of first row d-transition metal complexes with N-substituted sulfonamides

“…Minimum inhibitory concentration (MIC) for antibacterial activity. The preliminary antibacterial screening showed that compounds (4), (12), (16), (20) and (24) were the most active ones (above 80%). These compounds were therefore, selected for antibacterial minimum inhibitory concentration (MIC) studies (Table V).…”