Antibacterial, Antifungal, and Cytotoxic Activities of<i>Distictis buccinatoria</i>.

Rojas, María Gabriela; Navarro, Vı́ctor; Alonso, Daniel F.; Rios, Marı́a Yolanda; Tortoriello, Jaime; Román-Ramos, Rubén

doi:10.1080/13880200701214847

Cited by 8 publications

(7 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although, D. buccinatoria is used in traditional medicine for the treatment of inflammation related diseases, only cytotoxic, antimicrobial and antifungal activities had been described for integrate extracts from this plant (Rojas et al, 2007). This is the first report that confirms the traditional use of "Tonacaxochilt" as anti-inflammatory treatment.…”

Section: Discussionmentioning

confidence: 77%

“…Distictis buccinatoria has been used, since, pre-Hispanic times for medical purposes (De la Cruz, 1964;Moreno, 1971). Now a days, empirical midwives and herbalists in the state of Morelos use the decoction of its leaves and flowers to treat cough, angina, inflammation, pharyngitis and coughs with blood (Rojas et al, 2007). Previous studies demonstrated that this plant shows anti-microbial activity against Staphylococcus aureus, Streptococcus pyogenes, Streptococcus faecalis, bacteria and Trichophyton mentagrophytes, Trichophyton rubrum dermatophytes, as well as cytotoxicity against cancerous line cell KB (Rojas et al, 2007).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Anti-inflammatory Extracts and Coumaroyl Ursolic Acid Derivatives from Distictis buccinatoria

Ruiz¹,

Rojas-Bibriesca²,

Nuñez³

et al. 2015

International J. of Pharmacology

View full text Add to dashboard Cite

Three ascendant polarities extracts (n-hexane, dichloromethane and methanol) from Distictis buccinatoria were analyzed for their anti-inflammatory activity in the TPA mice ear edema assay. The dichloromethane extract (DbDE) shown the highest percentage of edema inhibition (90.47%; ED 50 = 0.036 mg earG 1 and E max = 90.9%). The chemical bio-guided study of this extract allowed to obtain an anti-inflammatory fraction DbC1F4 (95.8%; D 50 = 0.49 mg earG 1 and E max = 99.01%) and sub-fraction DbC2F3 (93.44% of edema inhibition). The compounds (1) 3-O-(E)-p-coumaroyl ursolic acid, (2) 3-O-(Z)-p-coumaroyl ursolic acid and (3) ursolic acid were isolated from this last fraction. These results give a scientific basis to the traditional uses of this Mexican medicinal plant, which could be standardized in the content of coumaroyl ursolic acid derivatives for future investigations of this species in treatment of inflammation related illness.

show abstract

Section: Discussionmentioning

confidence: 77%

Section: Introductionmentioning

confidence: 99%

Anti-inflammatory Extracts and Coumaroyl Ursolic Acid Derivatives from Distictis buccinatoria

Ruiz¹,

Rojas-Bibriesca²,

Nuñez³

et al. 2015

International J. of Pharmacology

View full text Add to dashboard Cite

show abstract

“…The multi-well plates were incubated for 72 h under the same conditions, after which, the cell concentration for each treatment was determined by quantifying the protein with the Lowry method. The results are expressed as the extract concentration that inhibited growth by 50%, i.e., the median inhibitory concentration (IC 50 ) relative to the negative control [34]. Values were estimated from the treatment semi-log concentrations versus the percentage of viable cells.…”

Section: Cytotoxic Activitymentioning

confidence: 99%

Spontaneous Regeneration of Plantlets Derived from Hairy Root Cultures of Lopezia racemosa and the Cytotoxic Activity of Their Organic Extracts

Vargas-Morales

Moreno-Anzúrez

Téllez-Román

et al. 2022

Plants

View full text Add to dashboard Cite

A histological analysis was performed with the aim of elucidating the spontaneous regeneration process of the hairy root lines LRT 2.3 and LRT 6.4, derived from Lopezia racemosa leaf explants and genetically transformed with the Agrobacterium rhizogenes strain ATCC15834/pTDT. The analysis showed both lines regenerate via indirect somatic embryogenesis; LRT 6.4 also regenerated by direct organogenesis. The morphogenic characteristics of the regenerated plantlets from both lines showed the typical characteristics, described previously, including a higher number of axillary shoot formation, short internodes, and plagiotropic roots compared with wild-type seedlings. The regeneration process occurred without the addition of plant growth regulators and was linked to the sucrose concentration in the culture medium. Reducing the sucrose concentration from 3% to 2%, 1%, and 0.5% increased the regeneration rate in LRT 6.4; the effect was less pronounced in LRT 2.3. The cytotoxic activity of different organic extracts obtained from roots and shoots were evaluated in the cancer cell lines HeLa (cervical carcinoma), HCT-15 (colon adenocarcinoma), and OVCAR (ovary carcinoma). The hexane and dichloromethane extracts from roots of both lines showed cytotoxic activity against the HeLa cell line. Only the dichloromethane extract from the roots of PLRT 2.3 showed cytotoxic activity against the OVCAR cell line. None of the methanol extracts showed cytotoxic activity, nor the shoot extracts from any solvent.

show abstract

“…A.H. Gentry (Bignoniaceae), is a native Mexican plant which has been used by empirical midwives and herbalists in the state of Morelos in Mexico to treat cough, angina, inflammation, pharyngitis, and coughs [5]. A.H. Gentry (Bignoniaceae), is a native Mexican plant which has been used by empirical midwives and herbalists in the state of Morelos in Mexico to treat cough, angina, inflammation, pharyngitis, and coughs [5].…”

Section: Distictis Buccinatoria Plantmentioning

confidence: 99%

Development of Biomaterials With Therapeutically Medicinal Application

et al. 2009

View full text Add to dashboard Cite

A biomaterial is a non-biological material used in a medical device in order to interact with biological systems. Many different types of materials such as metals, ceramic or natural and synthetic polymers can be included in this definition. Most of the time they are used as mixed materials where the combination of two or more substances with their own characteristics results in a new material whose features will be superior to the ones of its components for the achievement of the objectives preset [1]. According to the length and characteristics of the contact with an organism, biomaterials can be classified as temporal and permanent and of intra or extra corporal location. According to their functions they can be used as support, diagnostic or treatment [2]. Some biomaterials contain drugs and they are considered as medicines, others may include living cells and become the so called “hybrid biomaterials”.Elaboration of a biomaterial from a medicinal plant called Tonacaxochitl (Distictis buccinatoria (D.C.)) is presented in this work. The Tonacaxochitl is an endemic plant from Morelos state in Mexico. By means of solvents, active principles were extracted from the plant in an integral way. Obtained product (plant extract) was mixed with materials like clay and toncil. The biomaterial obtained from clay and toncil has shown anti-inflammatory activity, what makes it a useful tool for topic treatment of inflammation. Tests are being carried out with different extract concentrations to specify suitable concentrations to get effects on specific parts of the human body.

show abstract

Antibacterial, Antifungal, and Cytotoxic Activities ofDistictis buccinatoria.

Cited by 8 publications

References 24 publications

Anti-inflammatory Extracts and Coumaroyl Ursolic Acid Derivatives from Distictis buccinatoria

Anti-inflammatory Extracts and Coumaroyl Ursolic Acid Derivatives from Distictis buccinatoria

Spontaneous Regeneration of Plantlets Derived from Hairy Root Cultures of Lopezia racemosa and the Cytotoxic Activity of Their Organic Extracts

Development of Biomaterials With Therapeutically Medicinal Application

Contact Info

Product

Resources

About