Antibacterial and Solubility Analysis of Experimental Phytotherapeutic Paste for Endodontic Treatment of Primary Teeth

Freire, Aldelany Ramalho; Freire, Déborah Ellen Wanderley Gomes; Sousa, Simone Alves de; Serpa, Eliane Batista de Medeiros; Almeida, Leopoldina de Fátima Dantas de; Cavalcanti, Yuri Wanderley

doi:10.1590/pboci.2021.005

Cited by 5 publications

(9 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…La pasta CTZ ha demostrado una buena actividad antimicrobiana sobre la polimicrobiota típica de las infecciones endodóncicas. [12][13][14][15] Es importante considerar que los conductos radiculares de los dientes primarios con pulpas necróticas son infectados por una polimicrobiota con predominio de microorganismos anaerobios, bacilos pigmentados (porphyromonas y prevotella), algunos aerobios y estreptococos. 19 Las especies frecuentemente encontradas son Porphyromonas gingivalis (73,3%), Prevotella intermedia (6,7%), Porphyromonas nigrescens (86,7%), Fusobacterium alocis (73,3%), y Treponema forsythia (26,7%).…”

Section: Discussionunclassified

See 1 more Smart Citation

Pasta CTZ para abordaje endodóncico de dientes primarios: Una revisión narrativa de la literatura

Zeno

Marañón‐Vásquez

Primo

et al. 2022

Rev. Odontopediatr. Latinoam.

View full text Add to dashboard Cite

Introducción: La afectación pulpar irreversible de los dientes primarios representa un desafío para la endodoncia en odontopediatría. Sobre la base del enfoque de esterilización de lesiones y reparación de tejidos (LSTR-Lesion Sterelization and Tissue Repair), se ha propuesto una técnica endodóncica no instrumental que utiliza pastas antibióticas. La pasta antibiótica CTZ, que contiene una mezcla de cloranfenicol, tetraciclina, óxido de zinc y eugenol, tiene potencial para uso en la técnica endodóncica no instrumental en pacientes pediátricos. Objetivo: El objetivo de este trabajo es presentar una revisión narrativa de la literatura sobre la pasta antibiótica CTZ, en lo relacionado a capacidad antimicrobiana, biocompatibilidad y aspectos clínicos. Materiales y métodos: Se realizaron búsquedas en las bases de datos PUBMED, BVS, WEB OF SCIENCE, COCHRANE y SCOPUS utilizando los términos “ctzpaste”, “ctz”, “tooth, deciduous” y “primary molars” sin restricción de idioma, con fecha limitada de 2015 hasta enero de 2021. Resultados: Después de eliminar los duplicados, se obtuvieron 13 artículos. La pasta CTZ mostró una actividad antimicrobiana satisfactoria en Enterecoccus faecalis, Staphylococcus aureus, Klebisiella pneumonia, Escherichia coli y Candida albicans. Los estudios in vitro e in vivo han demostrado que la pasta tiene biocompatibilidad. La frecuencia de éxito clínico varió del 37% al 100% y el éxito radiográfico del 29,7% al 97,4%. Conclusiones: Aunque se necesitan más estudios que contribuyan a un mejor nivel de la evidencia, puede afirmase que la pasta CTZ una es alternativa para los casos de afectación pulpar en dientes primarios, inclusive en el ámbito de la salud pública.

show abstract

Section: Discussionunclassified

“…Se obtuvieron cuatro estudios de laboratorio utilizando diferentes metodologías: difusión en agar 12,13 y contacto directo. 14,15 La pasta CTZ mostró una actividad antimicrobiana satisfactoria en Enterecoccus faecalis, Staphylococcus aureus, Klebisiella pneumonia, Escherichia coli y Candida albicans.…”

Section: Actividad Antimicrobianaunclassified

Pasta CTZ para abordaje endodóncico de dientes primarios: Una revisión narrativa de la literatura

Zeno

Marañón‐Vásquez

Primo

et al. 2022

Rev. Odontopediatr. Latinoam.

View full text Add to dashboard Cite

show abstract

“…The ideal characteristics of a root canal filling material in primary teeth include biocompatibility, broad antimicrobial activity, to be a bactericidal material or not to encourage microbial growth, degradation similar to the physiological tooth root resorption, easy filling and removal of the material from the root canal system, resorbable in cases of periapical extrusion, no aggression to the periapical tissues and tooth germ of the permanent tooth, radiopacity, and no discoloration of the tooth. 9,15,16 Considering the limitations of the root canal instrumentation and the obstacles to the intracanal irrigants, the use of root canal filling material with antimicrobial activity is of great importance for the success of the endodontic treatment in primary dentition. 10,13 Numerous researchers investigated the antimicrobial spectrum of action of the materials used and the results obtained demonstrated significant divergence.…”

Section: Aimmentioning

confidence: 99%

“…5 In 2020, Brazilian researchers investigated an experimental phytotherapeutic paste containing terpineol and cinnamaldehyde for endodontic treatment of primary teeth and reported antimicrobial activity against E. faecalis similar to the ZOE paste. 9 Kirplani et al found a superior antimicrobial efficiency of Aloe vera and sterile water as an obturating material in primary teeth compared to ZOE, Metapex, and calcium hydroxide. 6 In 2008, Fabiane et al determined that MTA had high levels of antimicrobial activity in comparison with ZOE and a combination of calcium hydroxide and iodoform.…”

Section: Calcium Hydroxide + Iodoformbased Pastesmentioning

confidence: 99%

“…8 The complex anatomy of the root canal system (sharp curvatures and lateral canals) and the physiological resorption (no apical limit, occurs irregularly, not seen radiographically oftentimes) make the access and the instrumentation hard. 3,9,10 In addition, Faria et al found that several resistant microorganisms could persist after biomechanical preparation and use of intracanal irrigants. 11 Observing the importance of this aspect of the endodontic infections in primary dentition, a significant number of researchers emphasized the antimicrobial activity of the root canal filling material.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Root canal filling materials in primary teeth - review

Shindova¹

2021

View full text Add to dashboard Cite

Inadequate treatment of endodontic infections in primary teeth results in a loss of а deciduous tooth or abnormality in the development of hard dental tissues of the permanent successor. The main goal is to maintain the integrity and health of the primary tooth until their physiological exfoliation. The success of the endodontic treatment depends on the antimicrobial activity of the root canal filling material that contributes to the elimination or reduction of the microbial infection of the root canal system. The aim of this article is to systematically review the contemporary scientific literature concerning the root canal filling materials used in primary teeth. A critical evaluation of the antimicrobial activity, as well as the advantages and disadvantages of the investigated materials, has been made. Knowledge of the composition and characteristics of the available obturating materials is a useful advantage to dentists to address the functional problems associated with endodontic infections in very young patients. Future studies should also seek and compare the long-term effects of the use of traditional and alternative intracanal materials.

show abstract

Lesion sterilization and tissue repair with chloramphenicol, tetracyline, zinc oxide/eugenol paste versus conventional pulpectomy: A 36‐month randomized controlled trial

Castro

Lima

et al. 2023

Int J Paed Dentistry

View full text Add to dashboard Cite

Background Endodontic treatment of primary molars represents one of the challenges in pediatric dentistry. There is a lack of consensus in the literature about the endodontic techniques and filling paste for primary teeth with pulp necrosis. Aim To compare the effectiveness of the LSTR technique (lesion sterilization and tissue repair) with CTZ paste (chloramphenicol, tetracycline, zinc oxide and eugenol) and pulpectomy with ZOE paste (zinc oxide and eugenol) in the treatment of primary molars with pulp necrosis. Design Eighty‐eight primary molars with pulp necrosis from 70 children between the ages of 3 and 8 years were included. The teeth were randomized to the LSTR with CTZ paste group or pulpectomy with ZOE paste group. Clinical and radiographic evaluations were performed at 18, 24, 30 and 36 months. Results At 36 months, clinical success was 86.4% in LSTR with CTZ paste and 90.9% in pulpectomy with ZOE paste (p = .45). Radiographic success was 43.2% in both groups (p = 1.00). The overall success was 40.9% in LSTR with CTZ paste and 43.2% in pulpectomy with ZOE paste (p = 1.00). Conclusion After 36 months of evaluation, the effectiveness of the LSTR technique with CTZ paste and pulpectomy with ZOE paste was similar for the treatment of primary molars with pulp necrosis.

show abstract

Antibacterial and Solubility Analysis of Experimental Phytotherapeutic Paste for Endodontic Treatment of Primary Teeth

Cited by 5 publications

References 27 publications

Pasta CTZ para abordaje endodóncico de dientes primarios: Una revisión narrativa de la literatura

Pasta CTZ para abordaje endodóncico de dientes primarios: Una revisión narrativa de la literatura

Root canal filling materials in primary teeth - review

Lesion sterilization and tissue repair with chloramphenicol, tetracyline, zinc oxide/eugenol paste versus conventional pulpectomy: A 36‐month randomized controlled trial

Contact Info

Product

Resources

About