Antibacterial and Larvicidal Activity of Silver Nanoparticles Synthesized by the Leaf Extract of Andrographis serpyllifolia Wight

R, Madhankumar; Sivasankar, Palaniappan; Kalaimurugan, Dharman; Murugesan, Subban

doi:10.1007/s10876-019-01679-5

Cited by 16 publications

(6 citation statements)

References 39 publications

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“…It shows promising potential for controlling different pathogens. With multiple applications, nanoparticle research plays a vital role in the fields such as cancer study [1] , larvicidal and insecticidal activity [2] and plant disease control in agricultural sciences [3] . Biological activities like antibacterial, antifungal, anticancer [4] , anti-inflammatory, antiviral, cardioprotection [5] , wound healing [6] , and biosurfactants [7] helped nanotechnology to gain enormous popularity within a short time.…”

mentioning

confidence: 99%

Amycolatopsis sp. strain MN235945 Mediated Biosynthesis of Silver Nanoparticles: Characterization, Antimicrobial and Anticancer Activity against HeLa and MCF-7 Cell Lines

Swamy¹,

Bhat²,

Nayaka³

2022

IJPS

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Swamy et al.: Anticancer activity of Amycolatopsis sp. mediated Silver NanoparticlesThe current study investigated about the biogenic synthesis and evaluation of biological activities of Amycolatopsis sp. strain MN235945 fabricated silver nanoparticles and their characterization by ultraviolet-visible spectroscopy, fourier transform infrared spectroscopy, high resolution-transmission electron microscopy, energy dispersive X-ray spectroscopy, X-ray diffractometry and zeta potential analysis. The most potent isolate Amycolatopsis sp. strain MN235945 was identified by morphological and genotypic characterization and biological activity of silver nanoparticles was studied via antimicrobial and anticancer activity assays. The synthesized silver nanoparticles with spherical shape and polydispersed nature showed ultraviolet visible spectroscopy, absorption maximum at 417 nm with the smallest size of 19.40 nm. The presence of various biological functional groups and different elemental composition of silver nanoparticles were determined along with zeta potential value of -34.8 mV; whereas, the X-ray diffractometry analysis revealed the specific Bragg's diffraction peaks for metallic silver. The silver nanoparticles with increased antimicrobial activity significantly inhibited cervical adenocarcinoma HeLa and human breast cancer MCF-7 tumour cells with IC 50 values of 81.12 and 235.45 µg/ml respectively. These encouraging results obtained via low-cost green synthesis of silver nanoparticles from marine Amycolatopsis sp. strain MN235945 provide helpful information for further research and designing an anticancer agent in coming years using Amycolatopsis sp. strain MN235945 mediated silver nanoparticles with minimal side effects.

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confidence: 99%

Amycolatopsis sp. strain MN235945 Mediated Biosynthesis of Silver Nanoparticles: Characterization, Antimicrobial and Anticancer Activity against HeLa and MCF-7 Cell Lines

Swamy¹,

Bhat²,

Nayaka³

2022

IJPS

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“…With an average size of 24.1 nm and a range of 3.4 nm–71.6 nm, the silver nanoparticles were spherical in shape. The authors suggested that AgNPs could be a potential larvicidal agent for controlling mosquito-borne diseases and safeguarding human populations ( Madhankumar et al, 2020 ). More examples of plant-based AgNPs having wound-healing properties are mentioned in Table 6 .…”

Section: Medicinal Properties Of Silver Nanoparticlesmentioning

confidence: 99%

Plant-mediated synthesis of silver nanoparticles: unlocking their pharmacological potential–a comprehensive review

Dhir,

Chauhan,

Subham

et al. 2024

Front. Bioeng. Biotechnol.

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In recent times, nanoparticles have experienced a significant upsurge in popularity, primarily owing to their minute size and their remarkable ability to modify physical, chemical, and biological properties. This burgeoning interest can be attributed to the expanding array of biomedical applications where nanoparticles find utility. These nanoparticles, typically ranging in size from 10 to 100 nm, exhibit diverse shapes, such as spherical, discoidal, and cylindrical configurations. These variations are not solely influenced by the manufacturing processes but are also intricately linked to interactions with surrounding stabilizing agents and initiators. Nanoparticles can be synthesized through physical or chemical methods, yet the biological approach emerges as the most sustainable and eco-friendly alternative among the three. Among the various nanoparticle types, silver nanoparticles have emerged as the most encountered and widely utilized due to their exceptional properties. What makes the synthesis of silver nanoparticles even more appealing is the application of plant-derived sources as reducing agents. This approach not only proves to be cost-effective but also significantly reduces the synthesis time. Notably, silver nanoparticles produced through plant-mediated processes have garnered considerable attention in recent years due to their notable medicinal capabilities. This comprehensive review primarily delves into the diverse medicinal attributes of silver nanoparticles synthesized using plant-mediated techniques. Encompassing antimicrobial properties, cytotoxicity, wound healing, larvicidal effects, anti-angiogenesis activity, antioxidant potential, and antiplasmodial activity, the paper extensively covers these multifaceted roles. Additionally, an endeavor is made to provide an elucidated summary of the operational mechanisms underlying the pharmacological actions of silver nanoparticles.

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“…The colourless solution turned dark brown, confirms the presence of fabricated AgNPs. After the solution was prepared, the nanoparticles were collected by centrifuging it at 10,000 rpm while filtering the solution via filter paper to remove impurities [42].…”

Section: Synthesis Of Agnpsmentioning

confidence: 99%

Green synthesized silver nanoparticles using Andrographis macrobotrys Nees leaf extract and its potential to antibacterial, antioxidant, anti-inflammatory and lung cancer cells cytotoxicity effects

Sivakumar

Murugesan

Ragavendran

et al. 2023

Inorganic Chemistry Communications

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Antibacterial and Larvicidal Activity of Silver Nanoparticles Synthesized by the Leaf Extract of Andrographis serpyllifolia Wight

Cited by 16 publications

References 39 publications

Amycolatopsis sp. strain MN235945 Mediated Biosynthesis of Silver Nanoparticles: Characterization, Antimicrobial and Anticancer Activity against HeLa and MCF-7 Cell Lines

Amycolatopsis sp. strain MN235945 Mediated Biosynthesis of Silver Nanoparticles: Characterization, Antimicrobial and Anticancer Activity against HeLa and MCF-7 Cell Lines

Plant-mediated synthesis of silver nanoparticles: unlocking their pharmacological potential–a comprehensive review

Green synthesized silver nanoparticles using Andrographis macrobotrys Nees leaf extract and its potential to antibacterial, antioxidant, anti-inflammatory and lung cancer cells cytotoxicity effects

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