Antibacterial and Antioxidant Activities of Dacryodes edulis Methanolic Leaf Extract

Oyetunji, Olasunkanmi; Opeyemi, A Adeeyo

doi:10.9734/jamps/2017/33831

Cited by 5 publications

(5 citation statements)

References 18 publications

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“…These findings concur with those obtained by Aristimunha et al (2016) and Ogbe and Affiku (2012) . Proportionately, the amounts determined from different plant parts in this study (see Table 2 ) compare well with those reported in other studies evaluating D. edulis phytochemical composition ( Ogboru, 2015 ; Ebana et al, 2016 ; Okolo et al, 2016 ; Oyetunji and Opeyemi, 2017 ). These compounds have been noted to possess bactericidal, virucidal, fungicidal, and antiparasitical properties which can be exploited in pharmaceutical medicine or animal feed additives.…”

Section: Discussionsupporting

confidence: 89%

“…The phytochemical analysis of the three D. edulis plant parts was determined qualitatively ( Nwokonkwo, 2014 ; Oyetunji and Opeyemi, 2017 ) and quantitatively ( Madhurima et al, 2014 ) using three replicate for each of the parts. While the proximate analysis was carried out for all experimental diets in which the dry Matter (DM) was determined by drying samples at 105 °C overnight.…”

Section: Data Collectionmentioning

confidence: 99%

“…Studies by Valenzuela-Grijalva et al (2017) showed that the D. edulis seed, leave, stem, and bark also showed antimicrobial properties when used in vitro against resistant strain of Staphylococcus aureus . Further, findings from a study by Oyetunji and Opeyemi (2017) indicate that various parts of the D. edulis have broad spectrum antibacterial activity. Decoctions from different parts of the plant are used to relieve certain digestive disorders caused by microbial infection ( Ebana et al, 2016 ).…”

Section: Introductionmentioning

confidence: 99%

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Effect of feed supplementation of Dacryodes edulis parts’ powder as prebiotic on the growth traits, ceca microbiota and blood parameters of local chickens

Tangomo¹,

Keambou

Gicheha

et al. 2020

Translational Animal Science

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This study aimed at testing the efficacy and safety of Dacryodes edulis plant parts in diets fed to chicken. The plant has potential for use as a natural prebiotic to substitute the conventionally used antibiotic growth promoters in poultry production. Phytochemical analyses of the plant leaves, stem, and bark combination (stembark) and seed powders from the D. edulis were carried out. The powder from the three D. edulis plant parts were used as supplement in formulating six experimental diets tested in this study. The diets were TL0Ed (0.5% leaves powder), TL1Ed (1.0% leaves powder), TB0Ed (0.5% stembark powder), TB1Ed (1.0% stembark powder), TS0Ed (0.5% seeds powder), and TS1Ed (1.0% seeds powder). Besides, a positive (T+ positive control; 0.5-g oxytetracycline as recommended by the manufacturer) and a negative (T- negative control; having no commercial antibiotic and no plant supplement) diets were prepared for comparison purposes. The diets were fed to a total of 288 dual-purpose chicken for a period of 14 weeks. The chicken growth and body composition characteristics, blood chemistry, and microbiota count were collected and used as indicators of the plant parts efficacy and safety. The analysis of the D. edulis plant parts significantly differed (P ≤ 0.05) in their phytochemical contents. The initial body weight and feed conversion efficiency ratios were not significantly different (P ≥ 0.05) between and among treatment groups. However, significant differences (P ≤ 0.05) were detected in the feed intake and body weight gain at eighth week. Live weight at eighth week was significantly different (P ≤ 0.05) with its values ranging between 503.32 and 614.93 g for treatments TL1Ed and TNeg-, respectively. The dietary treatment of D. edulis leaves, stembark, and seed powder at the two inclusion levels significantly (P ≤ 0.05) decreased the colonies forming unit of Escherichia coli and Salmonella sp. as compared with negative control treatment in the eighth week phase. The level of glucose, total cholesterol, triglycerides, aspartate aminotransferase, alanine amino transferase, alkaline phosphatase, and the packed cell volume did not differ significantly (P ≥ 0.05) between and among dietary D. edulis treatments. The findings from this research provide crucial information on the efficacy and safety of D. edulis plant parts. This is an important step in testing the potential of the plant in use as a prebiotic in chicken feeds production.

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Section: Discussionsupporting

confidence: 89%

Section: Data Collectionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Effect of feed supplementation of Dacryodes edulis parts’ powder as prebiotic on the growth traits, ceca microbiota and blood parameters of local chickens

Tangomo¹,

Keambou

Gicheha

et al. 2020

Translational Animal Science

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“…Previous studies have reported antibacterial activity of the ethyl acetate fraction of D. edulis leaves against Staphylococcus aureus , Klebsiella pneumoniae , and P. aeruginosa , with inhibition zones of 29, 28, and 25 mm, respectively [ 83 ]. Methanol extraction of D. edulis leaves also showed antibacterial activity against various bacteria, including Bacillus stearothermophilus , K. pneumoniae , Bacillus polymyxa , Citrobacter freundii , P. aeruginosa , Trueperella pyogenes , Enterococcus faecalis , Escherichia coli , Micrococcus luteus , Shigella sp., and S. aureus , with inhibition diameters ranging from 12.0–23.3 mm, compared to 13.0–31.0 and 18.3–29.3.5 mm for streptomycin and ampicillin, respectively [ 84 ]. The flavonoid content of D. edulis exhibited antimicrobial activity against Proteus mirabilis and Candida albicans with IC 50 values of 5 and 10 mg/mL, respectively [ 85 ].…”

Section: Bioactivity Studiesmentioning

confidence: 99%

The Genus Dacryodes Vahl.: Ethnobotany, Phytochemistry and Biological Activities

Swana,

Tsakem,

Tembu

et al. 2023

Pharmaceuticals

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Dacryodes Vahl. species, belonging to the Burseraceae family, are widely used in traditional medicine in tropical regions to treat a range of ailments including malaria, wounds, tonsillitis, and ringworms. This review discusses the distribution, ethnobotanical uses, phytochemistry, and bioactivities of Dacryodes species. The intent is to spur future research into isolating and identifying key active principles, secondary metabolites, and crude extracts, and evaluating their pharmacological and toxicological effects, as well as the mechanism of actions to understand their medicinal benefits. A systematic review of scientific electronic databases from 1963 to 2022 including Scifinder, Scopus, Pubmed, Springer Link, ResearchGate, Ethnobotany Research and Applications, Google Scholar, and ScienceDirect was conducted with a focus on Dacryodes edulis (G.Don) H.J. Lam and Dacryodes rostrata (Blume) H.J. Lam. Pharmacological data revealed that D. edulis isolates contain secondary metabolites and other phytochemical groups belonging to the terpenoids class with anti-microbial, anticancer, antidiabetic, antiinflammatory and hepatoprotective activities, highlighting its pharmacological potential in the therapy or management of diverse cancers, cardiovascular, and neurological diseases. Thus, phytochemicals and standardized extracts from D. edulis could offer safer and cost-effective chemopreventive and chemotherapeutic health benefits/regimen, or as alternative therapeutic remedy for several human diseases. Nevertheless, the therapeutic potential of most of the plants in the genus have not been exhaustively explored with regard to phytochemistry and pharmacology, but mostly complementary approaches lacking rigorous, scientific research-based knowledge. Therefore, the therapeutic potentials of the Dacryodes genus remain largely untapped, and comprehensive research is necessary to fully harness their medicinal properties.

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“…Antibacterial effect of the essential oil as well as the organic extracts of D. edulis plant has been reported [8,3]. It was indicated that the leaf extract of Dacryodes edulis possess broad spectrum antibacterial activity in a recent study [9].…”

Section: Introductionmentioning

confidence: 99%

Antioxidant and Antimicrobial Activities of Various Extracts from Safou (Dacryodes edulis) Cultivated in Côte d’Ivoire

Sika

Kadji

Ouattara

et al. 2021

MRJI

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Safou (Dacryodes edulis) is a fruit with very interesting nutritional and pharmacological properties. However, this fruit remains rather unknown to the Ivorian population. Aims: The objective of this study was to highlight the antioxidant and antimicrobial potential of the seed and pulp of Safou (Dacryodes edulis) cultivated in Côte d'Ivoire for its valorization. Study Design: Microbiological and biochemical studies Place and Duration of Study: Laboratory of Biotechnology and Food Microbiology,Abidjan, Côte d’Ivoire, between September 2020 and February 2021. Methodology: Aqueous, ethanolic and methanolic extracts of the pulp and seed of Safou were prepared. Moisture content, pH, yield, total polyphenols,diphényl-2-picrylhydrazyle (DPPH) radical scavenging testof the different extracts were determined.Aqueous, ethanolicand methanolicextracts of the seed and pulp at varying concentrations of 200 mg/mL, 100 mg/mL, 50 mg/mL, 25 mg/mL, 12.5mg/mL and 6.25 mg/mL was tested against human pathogens such asEscherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Klebsiellapneumoniae, Proteus mirabilis, Aspergillus fumigatus and Penicilliumchrysogenum. Results: pH, moisture content and yield ranged from 3.16 to 4.74; 9 to 18.30%; and 10.79 to 18.78%, respectively. Total polyphenol content ranged from 1.45 mgEAG/g to 4.56 mgEAG/g. The highest levels of total polyphenols were observed for the methanolic extracts of pulp. The different extracts strongly scavenged the DPPH radical with percentages of anti-free radical activity that varied from 50.76 to 64.43%.The antimicrobial susceptibility results of the methanolic extracts of D. edulis seed showed highest zones of inhibition to the microbial isolates tested. The microorganisms were resistant to the aqueous extracts of pulp and seed. Conclusion: The presence of bioactive compounds and the antimicrobial activity of Safou extracts could justify its use in the food and pharmaceutical fields.

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Antibacterial and Antioxidant Activities of Dacryodes edulis Methanolic Leaf Extract

Cited by 5 publications

References 18 publications

Effect of feed supplementation of Dacryodes edulis parts’ powder as prebiotic on the growth traits, ceca microbiota and blood parameters of local chickens

Effect of feed supplementation of Dacryodes edulis parts’ powder as prebiotic on the growth traits, ceca microbiota and blood parameters of local chickens

The Genus Dacryodes Vahl.: Ethnobotany, Phytochemistry and Biological Activities

Antioxidant and Antimicrobial Activities of Various Extracts from Safou (Dacryodes edulis) Cultivated in Côte d’Ivoire

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