Antibacterial Activity of the Crude Extracts and Fractionated Constituents of Myrtus communis

Mansouri, Shahla; Foroumadi, Alireza; Ghaneie, Teimour; Najar, Ahmad Gholamhosseinian

doi:10.1076/phbi.39.5.399.5889

Cited by 88 publications

(49 citation statements)

References 6 publications

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“…Consistent with previous studies, the essential oil was active against both methicillin resistant and sensitive S. aureus at concentrations ranging from 4-8 μL/mL, 21,30,32 . In nosocomial infections, E. faecalis were isolated more often than E. faecium.…”

Section: Discussionsupporting

confidence: 73%

Chemical Composition and Antimicrobial Activities of the Essential Oil fromMyrtus communisLeaves

Zomorodian

Moein

Lori

et al. 2013

Journal of Essential Oil Bearing Plants

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Abstract:Nosocomial pathogens are associated with increased hospital stay lengths and mortality rates. Increasing resistance to antibiotics makes the treatment of these infections more difficult. Novel antimicrobial compounds derived from natural sources may be useful for addressing antiobiotic resistance. The objective of this study is to determine the chemical composition and antimicrobial activities of essential oils from Myrtus communis L. (Myrtaceae) leaves against pathogens causing nosocomial infections. The chemical composition of essential oil from M. communis leaves was analysed by gas chromatography-mass spectrometry (GC-MS). The antimicrobial activity of the essential oil against bacteria and fungi was evaluated by broth micro-dilution as per the Clinical and Laboratory Standards Institute (CLSI) methods. GC-MS analysis revealed that the major constituents of the essential oil were α-pinene (39.2 %), 1,8-cineole (22.0 %), and linalool (18.4 %). The essential oil exhibited antimicrobial activity against all Gram positive and Gram negative bacteria with MICs in the range of 0.5-32 μL/mL and 8-64 μL/mL, respectively. MICs for the tested clinical and standard fungi were in the range of 0.03-16 μL/mL. The essential oil exhibited strong antibacterial and antifungal activities against all the causative agents of nosocomial infections examined, particularly against strains with antibiotic resistance. The essential oil from M. communis leaves is a potential source of novel antimicrobial agents for the treatment of nosocomial infections.

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Section: Discussionsupporting

confidence: 73%

Chemical Composition and Antimicrobial Activities of the Essential Oil fromMyrtus communisLeaves

Zomorodian

Moein

Lori

et al. 2013

Journal of Essential Oil Bearing Plants

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“…However, considerable variability in the composition of oils from different locations has been reported (Olga, Stavros, & Ioanna, 2007). Although many plants from the Myrtaceae family are reported to have antibacterial or antifungal activities (Mansouri, Foroumadi, Ghaneie, & Gholamhosseinian, 2001;Shahidi, 2004), very little has been reported on the antioxidant activity of this plant (Hayder et al, 2004;Romani et al, 2004).…”

Section: Introductionmentioning

confidence: 99%

Antioxidant activity and total phenolic compounds of myrtle extracts Actividad antioxidante y contenido de compuestos fenólicos totales en extractos de myrtus

Amensour

Sendra

Abrini

et al. 2010

CyTA - Journal of Food

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The total phenolic content, flavonoid content and antioxidant activity of methanol, ethanol, water and ethyl acetate extracts of the leaves and berries of myrtle (Myrtus communis) were measured. Total phenolic content was assessed by the Folin-Ciocalteau assay, total flavonoid content was assessed by a colorimetric method using rutin as standard flavonoid, whereas antioxidant activity was assessed by measuring the ability of the extracts to scavenge the 2,2 0 -azinobis (3-ethylbenzothiazoline-6-sulphonic acid) diammonium salt (ABTS þ ) radical. The results pointed to the significant antioxidant activities of the methanol and water extracts, the overall strength being in the order of methanol 4 water 4 ethanol 4 ethyl acetate in both, leaf and berry extracts. In all cases, the extracts obtained from leaves showed higher antioxidant activity and higher total phenolic and flavonoid contents than the corresponding extracts obtained from berries. The phenolic content exhibited a strong association (r 2 ¼ 0.9452) with antioxidant activity.Keywords: Myrtus communis; antioxidant activity; phenolic compounds; flavonoid Se determino´el contenido de compuestos feno´licos totales y de flavonoides, ası´como la actividad antioxidante de diferentes extractos (metanol, etanol, acetil e´ter y agua) de hojas y frutos de myrtus (Myrtus communis). El contenido de compuestos feno´licos totales se determino´mediante el me´todo de Folin-Ciocalteau, el contenido de flavonoides mediante un me´todo colorime´trico usando como flavonoide esta´ndar la rutina, mientras que la actividad antioxidante se determino´midiendo la capacidad de los extractos para captar el radical ABTS þ . Los resultados mostraron una significante actividad antioxidante de los extractos metano´licos y acuosos, siendo la intensidad de dicha actividad antioxidante en el siguiente orden: metanol 4 agua 4 etanol 4 acetil e´ter, tanto en el caso de los extractos procedentes de hojas como de frutos. Para todos los extractos, los procedentes de las hojas de myrtus presentaron mayor actividad antioxidante y mayor contenido en polifenoles totales y en flavonoides que los correspondientes extractos de frutos. El contenido total de compuestos feno´licos totales presento´una alta correlacio´n (r 2 ¼ 0,9452) con la actividad antioxidante.

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“…Ferulic acid were found in methanol (0,018 mg/g), ethanol (0,038 mg/g) and ethyl acetate (0,006 mg/g) extracts in low amounts while it was not determined in asetone extract. Other studies have shown mostly that essential oils of plant had strong antimicrobial activity [17][18][19][20]. However, It has known that classical extraction methods commonly used for the evaluation of antifungal activities of Myrtus communis.…”

Section: Resultsmentioning

confidence: 99%

Anti-candidal activities of some Myrtus communis L. extracts obtained using accelerated solvent extraction (ASE)

2014

J App Biol Biotech

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Candida albicans is a very important organism in production of acute and chronic infections. It can be reason of serious infections in human immune compromised patients as nosocominal infections. In this study, We researched new anti-candida agents from Myrtus communis extracts by ASE (Accelerated Solvent Extraction). We were also determined Gallic, Ferulic, Quercetin phenolic compounds known charged with antimicrobial activity by HPLC (High-performance Liquid Chromatography). Gallic acid (2,424 mg/g) and Quercetin (2,289 mg/g) were detected in high amounts in Acetone extract and Methanol extract while Ferulic (0,018 mg/g; 0,038 mg/g; 0,006mg/g) was recorded in low amounts in Methanol, Ethanol and Ethly acetate extracts, respectively. Methanol, Acetone, Ethanol and Ethly acetate extracts showed good anti-candida activity against C. albicans, with Minimum Inhibitory Concentration (MIC) ranging from 0.187 to 1,5 mg/mL; Minimum Fungicidal Concentration (MFC) ranging from 0,375 to 3 mg/mL.

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Antibacterial Activity of the Crude Extracts and Fractionated Constituents of Myrtus communis

Cited by 88 publications

References 6 publications

Chemical Composition and Antimicrobial Activities of the Essential Oil fromMyrtus communisLeaves

Chemical Composition and Antimicrobial Activities of the Essential Oil fromMyrtus communisLeaves

Antioxidant activity and total phenolic compounds of myrtle extracts Actividad antioxidante y contenido de compuestos fenólicos totales en extractos de myrtus

Anti-candidal activities of some Myrtus communis L. extracts obtained using accelerated solvent extraction (ASE)

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