Antibacterial activity of the aqueous extract of &lt;I&gt;Thonningia sanguinea&lt;/i&gt; against Extended-Spectrum-b-Lactamases (ESBL) producing &lt;i&gt;Escherichia coli&lt;/i&gt; and &lt;i&gt;Klebsiella pneumoniae&lt;/i&gt; strains

N'guessan, J. D.; Dinzedi, M R; Guessennd, Nathalie; Coulibaly, A; Dosso, M; Djaman, AJ; Guédé-Guina, F.

doi:10.4314/tjpr.v6i3.14659

Cited by 26 publications

(19 citation statements)

References 17 publications

(8 reference statements)

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“…These results are in line with other findings mentioning that for the bactericidal properties higher concentration is usually required to kill all bacterial cells [48] . Bactericidal nature is determined by lower concentration of extracts that kills all tested bacteria which is guided by MIC test.…”

Section: Discussionsupporting

confidence: 82%

Studies on bactericidal efficacy of pumpkin (Cucurbita moschata Duchesne) peel

2014

JCLM

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Section: Discussionsupporting

confidence: 82%

Studies on bactericidal efficacy of pumpkin (Cucurbita moschata Duchesne) peel

2014

JCLM

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“…The results showed significant inhibition with MIC values between 3.125 and 6.250 mg/ml 20 . In the present study, the MIC 90 of the different fractions varied between 5.5 and 80 μg/μl.…”

Section: Antimicrobial Activity Of Viola Odoratamentioning

confidence: 89%

Untitled

2011

IJPSR

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The aim of this study was to determine the antimicrobial activity of three selected Lebanese plants (Rheum rhaponticum, Olea europaea, and Viola Odorata) against Extended Spectrum Beta Lactamase (ESBL) -producing Escherichia coli and Klebsiella pneumoniae, and to identify the specific plant fraction responsible for the antimicrobial activity. The plants were extracted with ethanol to yield the crude extract which was further subfractionated by different solvents to obtain the petroleum ether, the dichloromethane, the ethyl acetate and the aqueous fractions. The Minimum Inhibitory Concentrations (MIC) and Minimum Bactericidal Concentrations (MBC) were determined using broth microdilution. The MICs ranged between 2.5 and 80 μg/μl. The majority of these microorganisms were inhibited by 80 and 40 μg/μl of the crude extracts. The dichloromethane fraction of Olea europea exerted a significant inhibitory effect on 90% of the tested strains. Ethyl acetate extracts of all selected plants presented antibacterial activity with high potency. Aqueous extracts of Rheum rhaponticum and Olea europaea exerted antimicrobial activity against the majority of the tested strains while Viola Odorata's aqueous extract showed less activity. This study constitutes a good example for the screening of antimicrobial activities of plants on highly resistant organisms of clinical importance; however, toxicity of these extracts needs more investigation.

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“…These are for example Erythrina vogelii, Potomorphe umbellata [39], Erythrina senegalensis, Bobgunnia madagascariensis, Waltheria lanceolata [13], Terminalia avicennioides, Phyllanthus discoideus, Ocimum gratissimum, Acalypha wilkesiana [14] and Thonningia sanguinea [15]. These are for example Erythrina vogelii, Potomorphe umbellata [39], Erythrina senegalensis, Bobgunnia madagascariensis, Waltheria lanceolata [13], Terminalia avicennioides, Phyllanthus discoideus, Ocimum gratissimum, Acalypha wilkesiana [14] and Thonningia sanguinea [15].…”

Section: Plants Used In Bacterial Disease Treatment In West Africamentioning

confidence: 99%

“…Among the plants found through investigations able to treat bacterial diseases that we have just mentioned, several species have been tested in vitro against MDR bacteria [13][14][15]. Furthermore, the research conducted is scattered among various laboratories without cooperative agreements.…”

Section: Introductionmentioning

confidence: 99%

West African Plants and Related Phytocompounds with Anti‐Multidrug‐Resistance Activity

Witabouna

Kagoyire

2008

New Strategies Combating Bacterial Infection

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Diseases due to multidrug resistant (MDR) bacteria have become a major health problem in developing as well as developed countries. Therapy of bacterial infections is a frequent problem due to the emergence of bacterial strains resistant to numerous antibiotics. In many west African countries, the prevalence of MDR bacteria is increasing despite the measures of control. This increase of MDR bacteria necessitates the search for new effective alternatives to replace antibacterial agents currently in use. In this instance, the plant kingdom is undoubtedly a valuable source for new antibiotics. Herbal medicine has been shown to have a genuine utility and rural population depens on it as primary health care. About 80% of the population in West Africa still use traditional medicine for treating diseases, both microbial and non-microbial origins. Ethnobotanical studies on west African medicinal plants has reasonably been done resulting into a collection of information which show that African medicinal plants could be source of leads compounds. A wide range of those medicinal plants have been studied for antibacterial activity against various bacteria, but few have included MDR bacteria. This chapter provides an overview of the West African plants and related phytocompounds with anti-MDR activity. An attempt has been made to summarize the information in order to highlight those promising medicinal plant in the treatment of diseases caused by multidrug resistant bacteria. The most promising are Erythrina senegalensis, Erythrina vogelii, Terminalia avicennioides, Momordica balsamina, Combretum paniculatum, Morinda lucida, Ocimum gratissimum and Trema guineensis. These plant species show a strong anti-MDR activity on MRSA, vancomycin resistant enterococci (VRE), Escherichia coli ESBL, Klebsiella pneumoniae ESBL and MDR-Salmonella typhi strains. The phytochemicals responsible for this activity are flavonoids, isoflavonoids, naphtoquinones, alkaloids, sesquiterpenoids, phenolic compounds and xanthones. Precise active principles, such as isowighteone, vogelin B and vogelin Cwith anti-MDR activity, have been isolated from Erythrina vogelii. The importance of MDR bacteria makes these data of special interest since many medicinal plants are used in traditional medicinal in places of West Africa where medical services are not in position to provide health care.New Strategies Combating Bacterial Infection. Edited by Iqbal Ahmad and Farrukh Aqil

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Antibacterial activity of the aqueous extract of <I>Thonningia sanguinea</i> against Extended-Spectrum-b-Lactamases (ESBL) producing <i>Escherichia coli</i> and <i>Klebsiella pneumoniae</i> strains

Cited by 26 publications

References 17 publications

Studies on bactericidal efficacy of pumpkin (Cucurbita moschata Duchesne) peel

Studies on bactericidal efficacy of pumpkin (Cucurbita moschata Duchesne) peel

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West African Plants and Related Phytocompounds with Anti‐Multidrug‐Resistance Activity

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