Antibacterial Activity of Silver Nanoparticles Synthesized by Using Extracts of Hedera helix

Abstract

Background: Silver nanoparticles (AgNPs) are one of the most widely applicable particles whose application is increasing in Nano world daily. Silver nanoparticles have expressed significant advances owing to wide range of applications in the field of bio-medical, sensors, antimicrobials, catalysts, electronics, optical fibers, agricultural, bio-labeling and the other areas. Green synthesis is the safe and easiest method of producing silver nanoparticles. Because of the production of the silver ions, silver nanoparticles are found to have the antibacterial activity.Objectives: The aim of this study was to investigate antibacterial activity of silver nanoparticles synthesized by using extracts of Hedera helix against Bacillus subtilis and Klebsiella pneumoniae. Methods: In this experimental study AgNPs were prepared by the reaction of 1mM silver nitrate and extracts of Hedera helix. Antibacterial activity of AgNPs was assessed by using disc diffusion method against Bacillus subtilis and Klebsiella pneumoniae. The AgNPs were characterized by UV-visible (vis) spectrophotometer, particle size analyzer by dynamic light scattering (DLS) method, transmission electron microscopy (TEM).Results: AgNPs obtained showed significantly higher antimicrobial activities against B. subtilis and K. pneumonia in comparison to both AgNO3 and raw plant extracts. Conclusions:Biological methods are a good competent for the chemical procedures, which are environment friendly and convenient.

Biologically active compounds of plant origin in medicine

“…Silver nanoparticles synthesised with the use of ivy extracts showed markedly higher antimicrobial activity against Gram-positive B. subtilis ATCC 1715 and Gramnegative K. pneumoniae ATCC 1290 strains in comparison to both AgNO 3 and raw plant extracts. Both these strains were characterised by similar sensitivity to silver nanoparticles and a similar growth inhibition zone under the influence of silver nitrate [Abbasifar et al 2017].…”

Common Ivy (Hedera Helix L.) as a Novel Green Resource in an Urban Biorefinery Concept

“…They concluded that the nanoparticles had significantly higher antimicrobial activity than either the extract alone or AgNO 3 . 110 Saponin-rich ethanolic CI extracts were also used to improve bacterial metabolism in biodegradation processes. Zdarta et al 111 found that the extract enhanced the viability of the cells (Acinetobacter calcoaceticus) during the biodegradation process.…”

“…Their research focused on the antibacterial activity of the nanoparticles against two bacteria strains. They concluded that the nanoparticles had significantly higher antimicrobial activity than either the extract alone or AgNO 3 . Saponin-rich ethanolic CI extracts were also used to improve bacterial metabolism in biodegradation processes.…”

Formulation and evaluation of azithromycin-loaded silver nanoparticles for the treatment of infected wounds

“…Research on Escherichia coli has confirmed that the accumulation of AgNPs on the cell membrane creates gaps in the bilayer's integrity, thereby increasing its permeability and resulting in bacterial cell death. Various studies have highlighted the strong correlation between the activity of AgNPs and their size ( Abbasifar et al, 2017 ; Ahmadi, 2020 ; Cai et al, 2012 ; Du et al, 2020 ; Elshazly et al, 2022 ; Hassan et al, 2016 ; Panda et al, 2011 ; Salem and Samir, 2018 ; Zachar, 2020 ). Infected wounds pose a significant challenge in healthcare, necessitating innovative therapeutic strategies.…”