Antibacterial activity of selected invertebrate species

Ali, Salwa Mansur; Siddiqui, Ruqaiyyah; Sagathevan, Kuppusamy; Khan, Naveed Ahmed

doi:10.1007/s12223-021-00860-6

Cited by 6 publications

(6 citation statements)

References 29 publications

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“…It is well known that one major issue in treating bacterial infections is the bacteria's ability to develop resistance to antibiotics. To overcome this problem, the discovery of new antimicrobial substances is still up-to-date [27,28]. For many years, the presence of antimicrobial substances, especially of bacterial and fungal origin, has been demonstrated.…”

Section: Discussionmentioning

confidence: 99%

Interaction between Acanthamoeba and Staphylococcus

Özcan Aykol,

Zeybek

2024

J Basic Microbiol

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Free‐living amoebae of the genus Acanthamoeba are infected by various bacteria in nature, and thus bacteria can protect themselves from adverse environmental conditions. Contrary to this ameba–bacteria relationship whether Acanthamoeba has antibacterial effects on bacteria is the different aspect of the relationship between these microorganisms. In this study, we investigate various Acanthamoeba strains have antibacterial effects on various Staphylococcus strains. Three environmental Acanthamoeba strains, isolated from various aquatic environments in Turkey, and Acanthamoeba castellanii ATCC 50373 standard strains were used in the study. The antistaphylococcal effect of cell‐free supernatant (CFS) obtained from these amoebae against 12 different Staphylococcus bacteria was investigated by colony counting method. In addition, the pathogenicity of the tested Acanthamoeba strains was determined using osmotolerance and thermotolerance tests. CFSs obtained from Acanthamoeba were found to have varying degrees of antistaphylococcal effects on various Staphylococcus strains (0%–100%). It was determined that the CFS of the standard Acanthamoeba strain showed 100% inhibitory effect against one clinical methicillin‐resistant Staphylococcus aureus strain (M2). Also, CFS of Ugöl strain showed 99.97% inhibitory effect against one clinical methicillin‐sensitive Staphylococcus epidermidis strain (L3). It was determined that all Acanthamoeba isolates had no pathogenic potential. According to the results, it has been observed that Acanthamoeba produces antibacterial substance(s) against Staphylococcus bacteria and that the ameba–bacteria relationship may also result in the detriment of the bacteria. Furthermore, the current study indicates that new and natural antimicrobial agents from Acanthamoeba can be used as an alternative to infections caused by Staphylococcus.

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Section: Discussionmentioning

confidence: 99%

Interaction between Acanthamoeba and Staphylococcus

Özcan Aykol,

Zeybek

2024

J Basic Microbiol

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“…So far, the constitutive production of AMPs and their storage in hemocyte granules has been confirmed in Acanthoscurria gomesiana ( Fukuzawa et al, 2008 ). While Ali et al (2021) tested the antibacterial activity of invertebrate lysates, including the prosoma and opisthosoma of spider Grammostola rosea , against Gram (−) Escherichia coli K1 and Gram (+) methicillin-resistant Staphylococcus aereus (MRSA). Both parts of the spider’s body showed antibacterial activity after 2 h of incubation with bacterial suspension at a concentration of 10 8 CFU/mL.…”

Section: Discussionmentioning

confidence: 99%

Immunostimulation of Parasteatoda tepidariorum (Araneae: Theridiidae) in juvenile and adult stages. Immunity reactions to injury with foreign body and Bacillus subtilis infection

Czerwonka¹,

Sawadro²,

Brożek³

et al. 2023

PeerJ

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To assess the immune potential of spiders, in the present study juvenile and adult females of Parasteatoda tepidariorum were exposed to Bacillus subtilis infection, injury by a nylon monofilament and a combination of both. The expression level of selected immune-related genes: defensin 1 (PtDEF1), lysozyme 1 (PtLYS1), lysozyme C (PtLYSC), lysozyme M1 (PtLYSM1), autophagy-related protein 101 (PtATG101), dynamin (PtDYN) and heat shock proteins (HSP70) (PtHSPB, PtHSPB2A, PtHSPB2B), production of lysozyme and HSP70 proteins, and hemocytes viability were measured. The obtained results indicated expression of the lysozyme, autophagy-related protein and HSP70 genes in both ontogenetic stages of P. tepidariorum. It has been also shown that the simultaneous action of mechanical and biological factors causes higher level of lysozyme and HSP70, cell apoptosis intensity and lower level of hemocytes viability than in the case of exposure to a single immunostimulant. Moreover, mature females showed stronger early immune responses compared to juveniles.

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“…These peptides (AMPs) also play important role in Ecdysis process of centipede Scolopendra subspinipes subspinipes [44]. These also show broad-spectrum antibacterial activity and [45]. Centipede venoms contain toxins which serve as AMPs and were found active against several bacteria [33].…”

Section: Antimicrobial Activitymentioning

confidence: 99%

Centipede Venom Toxins and Its Biomedical and Pharmacological Properties

Yadav

Upadhyay²

2022

Int J Pharm Pharm Sci

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The present review article explains venoms from various centipede species with their biomedical and pharmacological properties. Centipede venom is a natural source of bioactive proteins, peptides and other small molecules. These use venoms as defense arsenals to paralyze prey. This review paper sketch out important physiological effects like platelet aggregation, anticoagulant, phospholipase A2 and trypsin inhibiting activity. Centipede venom toxins selectively bind Kv2.1 channel and block them. Centipede venom disrupts cardiovascular, respiratory, muscular and nervous systems by targeting the broadly distributed KCNQ channels. It also signifies toxin-voltage-gated integrations and its inhibition. These peptides can be used for developing drugs for treatments as well as bio-insecticides for insect control.

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Antibacterial activity of selected invertebrate species

Cited by 6 publications

References 29 publications

Interaction between Acanthamoeba and Staphylococcus

Interaction between Acanthamoeba and Staphylococcus

Immunostimulation of Parasteatoda tepidariorum (Araneae: Theridiidae) in juvenile and adult stages. Immunity reactions to injury with foreign body and Bacillus subtilis infection

Centipede Venom Toxins and Its Biomedical and Pharmacological Properties

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