Antibacterial activity of polyeugenol against<i>staphylococcus aureus</i>and<i>escherichia coli</i>

Handayani, Dezi; Pranoto, Pranoto; Saputra, Dhany; Marliyana, Soerya Dewi

doi:10.1088/1757-899x/578/1/012061

Cited by 12 publications

(8 citation statements)

References 14 publications

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“…The dose‐dependent inhibitory activity was measured at varying concentrations of Ag‐CuO NCs (10–100 μg/mL) (Figure 9). One substantial limitation of this technique is the difficulty in determining the amount of antibacterial activity with subject to time 59 . The green fabricated hybrid Ag‐CuO NCs had potential growth inhibition on both Gram‐negative and Gram‐positive bacteria.…”

Section: Resultsmentioning

confidence: 99%

“…One substantial limitation of this technique is the difficulty in determining the amount of antibacterial activity with subject to time. 59 The green fabricated hybrid Ag-CuO NCs had potential growth inhibition on both Gram-negative and Gram-positive bacteria. Growth kinetics of hybrid Ag-CuO NCs decreased the bacteria population from 0 to 4 h, and after 4 h, both Gram-positive and Gram-negative bacteria overcome the NCs activity and increased their population (Figure 9a-c).…”

Section: Effect Of Ag-cuo Ncs On Growth Rate Of Pathogenic Microorganismmentioning

confidence: 99%

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Green synthesized AgNPs, CuONPs, and Ag‐CuO NCs to effective antibiofilm activities and their potential application in aquaculture

Manikandan,

Arumugam,

Abdul

et al. 2023

Applied Organom Chemis

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The expanded emergence of drug‐resistant microbes remains a concern to the scientific community in developing effective therapeutics. Approach of green chemistry based nanomaterials fabrication is in high demand, due to biocompatibility, non‐toxic, and high surface area that adheres more biomolecules on surface. Green fabricated silver nanoparticles (AgNPs), copper oxide nanoparticles (CuONPs), and silver–copper oxide nanocomposites (Ag‐CuO NCs) were characterized by fluorescence and Raman spectroscopy, field emission scanning electron microscopy (FE‐SEM) with energy‐dispersive X‐ray spectroscopy (EDX), and thermogravimetric (TG)/differential scanning calorimetry (DSC) analysis. Antibiofilm potential of green fabricated AgNPs, CuONPs, and Ag‐CuO NCs was tested against aquatic pathogenic microorganisms such as Aeromonas hydrophila, Pseudomonas aeruginosa, and Staphylococcus aureus. This present study deals with bacterial growth rate, biofilm inhibition, and antibiofilm architecture of AgNPs, CuONPs, and Ag‐CuO NCs under the visualization of confocal laser scanning electron microscopy (CLSM). The FE‐SEM technique was used to observe dense and compact structure (control without NPs treatment) with treatment of NPs that showed reduced amount of cell population in A. hydrophila, P. aeruginosa, and S. aureus. The effective antibiofilm inhibition of Ag‐CuO NCs was achieved by reducing micro‐colonies compared with AgNPs and CuONPs. The AgNPs, CuONPs, and Ag‐CuO NCs demonstrated antibiofilm properties against Gram‐negative and Gram‐positive bacteria, indicating a combinatorial effect of green fabricated NPs in combination with plant metabolites against pathogenic bacteria. As a result, aforementioned nano‐product merits further investigation in order to be used as a potent adjuvant therapy as antagonistic toward various bacterial diseases in aquaculture.

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Section: Resultsmentioning

confidence: 99%

Section: Effect Of Ag-cuo Ncs On Growth Rate Of Pathogenic Microorganismmentioning

confidence: 99%

Green synthesized AgNPs, CuONPs, and Ag‐CuO NCs to effective antibiofilm activities and their potential application in aquaculture

Manikandan,

Arumugam,

Abdul

et al. 2023

Applied Organom Chemis

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“…The antibacterial activity of RDFP ethanol extract showed that the inhibition diameter in accordance to the strong category [28]. The antibacterial activity was a resulted from secondary metabolites that contained in the extract, namely alkaloids, saponins, tannins, flavonoids, and triterpenoids [18].…”

Section: Discussionmentioning

confidence: 99%

“…The antibacterial activity produced was seen based on the diameter of the clear zone formed and it can be seen in table 6. Classification of the strength of antibacterial activity was seen based on the inhibition zone formed; if the diameter<5 mm was in the weak category, 5-9 mm was in the medium category, 10-19 mm was in the strong category, and diameter>20 mm was in the very strong category [28].…”

Section: Antimicrobial Activitymentioning

confidence: 99%

Utilization Red Dragon Fruit Peel (Hylocereus Polyrhizus) Ethanol Extract in Oral Thin Film Strip as a Mouth Freshener

APRILIANI,

LAILA,

PRASETYO

2024

Int J App Pharm

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Objective: The aim of this study was to formulate an oral thin film strip (OTFS) contained the red dragon fruit peel (RDFP) ethanol extract (Hylocereus polyrhizus) and evaluate the characteristic, stability and antibacterial activity against Streptococcus mutans (S. mutans). Methods: The film was made using the solvent casting method by adding a variety of concentration ethanol extract of red dragon fruit peel (5%, 10%, and 15%). The films were evaluated in organoleptic test, weight, thickness, pH, disintegration time, folding endurance, stability test and antibacterial activity. Results: The results showed that the film provided a distinctive color, aroma, and taste of the extract. The result of film evaluation had weight between 0.07-0.21 g, thickness between 0.10-0.20 mm, pH between 5.70-5.99, disintegration time between 34.99-49.13 s, and folding endurance between 321.00-812.83 times. The films were stable for 2 mo at a variety storage temperature (4±2 ℃, 28±2 ℃, and 40±2 ℃). The films showed antibacterial activity for 5%, 10% and 15% with the diameter of inhibition 8.5 mm, 10.8 mm, and 12.9 mm, respectively. Conclusion: Ethanol extract of RDFP can be utilized as a mouth freshener film that is stable for 2 mo and has antibacterial activity against S. mutans.

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“…For example, silver nanoparticles (AgNP) have emerged as a promising medical technique in recent years. AgNP have been shown to induce the generation of ROS on their surface in the cytoplasm, leading to intracellular oxidative stress, increased membrane permeability and inactivation of proteins and enzymes, and thus causing apoptosis or necrosis of tumour cells [131][132][133] . In addition, generation of ROS was elevated (>10 fold) and more GSH depletion was detected when cells were treated with smaller, more reactive AgNP 122 .…”

Section: Ros-producing Nanoparticlesmentioning

confidence: 99%

Reactive oxygen species (ROS): utilizing injectable antioxidative hydrogels and ROS-producing therapies to manage the double-edged sword

Newland

et al. 2021

J. Mater. Chem. B

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Antibacterial activity of polyeugenol againststaphylococcus aureusandescherichia coli

Cited by 12 publications

References 14 publications

Green synthesized AgNPs, CuONPs, and Ag‐CuO NCs to effective antibiofilm activities and their potential application in aquaculture

Green synthesized AgNPs, CuONPs, and Ag‐CuO NCs to effective antibiofilm activities and their potential application in aquaculture

Utilization Red Dragon Fruit Peel (Hylocereus Polyrhizus) Ethanol Extract in Oral Thin Film Strip as a Mouth Freshener

Reactive oxygen species (ROS): utilizing injectable antioxidative hydrogels and ROS-producing therapies to manage the double-edged sword

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