Antibacterial activity of PLAL synthesized nanocinnamon

Salim, A.A.; Bidin, Noriah; Lafi, Ahmad Sh. A.; Huyop, Fahrul

doi:10.1016/j.matdes.2017.07.014

Cited by 42 publications

(17 citation statements)

References 59 publications

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“…Furthermore, the absorption peaks were located at 1414 cm −1 assigned to carbon-hydroxyl groups (C-O) of aromatic amines that conjugates from aromatic ring in the Cin [25]. All these peaks confirmed the absorption of the cinnamon molecules and amide linkages of proteins attached on the surface of the NCs by different functional groups as reported earlier [9,25]. The observed shift was due to the presence of the cinnamaldehyde (main compound of cinnamon) and enlargement in the particle size.…”

Section: Resultssupporting

confidence: 83%

“…1a). This was due to the existence of the polyphenols, heterocyclic and cinnamaldehyde compounds in the Cin [9]. Furthermore, the absorption peaks were located at 1414 cm −1 assigned to carbon-hydroxyl groups (C-O) of aromatic amines that conjugates from aromatic ring in the Cin [25].…”

Section: Resultsmentioning

confidence: 98%

“…On top, various phytochemical studies on the cinnamon bark (cassia) have been long-established in vitro and vivo, revealing the existence of diterpenes, sesquiterpenoids, phenylpropanoids and flavonoids without any side effect or toxicity [8]. Despite these promising curative features, the extensive utilization of the cinnamon bark as an active biocidal agent is very minimal and low in pharmacodynamics action due to its poor dispersal and aqueous solubility as well as the lower absorption in the gastrointestinal process, and rapid metabolism to decrease foodstuffs (coumarin, di-tetra, hexahydrocinnamon, heterocyclic, eugenol, flavonoids and cinnamaldehyde) [6][7][8][9].…”

Section: Introductionmentioning

confidence: 99%

“…Of late, the organic nanoclusters (ONCs) emerged as an active agent in the area of advanced drug delivery, nanomedicinal, hyperthermia therapy and anti-bacterial purpose [9,10]. The conventional ONCs from their bulk sources can be obtained using the nanotechnology route.…”

Section: Introductionmentioning

confidence: 99%

“…It has been established that the nucleation of the cinnamon nanostructures can be critically sensitive to different types of growth liquid media and laser fluence (LF), signifying their uses towards biomedical applications [9,14]. The PLAL supported growth mechanism was clarified in terms of a simple process relating to the cavitation bubble dynamic forces, plasma generation, and the impact of pulse laser factors on the formation of the ONCs [17,18].…”

Section: Introductionmentioning

confidence: 99%

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Customised structural, optical and antibacterial characteristics of cinnamon nanoclusters produced inside organic solvent using 532 nm Q-switched Nd:YAG-pulse laser ablation

Salim

Bakhtiar

Ghoshal

et al. 2020

Optics & Laser Technology

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Spherical Cin-NCs were prepared in citric acid via nanosecond pulse laser ablation.• Physiochemical traits of these NCs strongly depended on the laser fluence.• Morphology and structure of Cin-NCs was controlled via laser fluence variation.• Cin-NCs containing cinnamaldehyde compounds showed strong antibacterial action.• Achieved Cin-NCs were shown to be favorable for antibacterial drug development.

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Section: Resultssupporting

confidence: 83%

Section: Resultsmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Customised structural, optical and antibacterial characteristics of cinnamon nanoclusters produced inside organic solvent using 532 nm Q-switched Nd:YAG-pulse laser ablation

Salim

Bakhtiar

Ghoshal

et al. 2020

Optics & Laser Technology

Self Cite

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Efficient Synthesis of Submicrometer‐Sized Active Pharmaceuticals by Laser Fragmentation in a Liquid‐Jet Passage Reactor with Minimum Degradation

Friedenauer,

Buck,

Eberwein

et al. 2023

Part & Part Syst Charact

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One challenge in the development of new drug formulations is overcoming their low solubility in relevant aqueous media. Reducing the particle size of drug powders to a few hundred nanometers is a well‐known method that leads to an increase in solubility due to an elevated total surface area. However, state‐of‐the‐art comminution techniques like cryo‐milling suffer from degradation and contamination of the drugs, particularly when sub‐micrometer diameters are aspired that require long processing times. In this work, picosecond‐pulsed laser fragmentation in liquids (LFL) of dispersed drug particles in a liquid‐jet passage reactor is used as a wear‐free comminution technique using the hydrophobic oral model drugs naproxen, prednisolone, ketoconazole, and megestrol acetate. Particle size and morphology of the drug particles are characterized using scanning electron microscopy (SEM) and changes in particle size distributions upon irradiation are quantified using an analytical centrifuge. The findings highlight the superior fragmentation efficiency of the liquid‐jet passage reactor setup, with a 100 times higher fraction of submicrometer particles (SMP) of the drugs compared to the batch control, which enhances solubility and goes along with minimal chemical degradation (<1%), determined by attenuated total reflection‐Fourier transform infrared spectroscopy (ATR‐FTIR), high‐performance liquid chromatography (HPLC), and X‐ray diffraction (XRD). Moreover, the underlying predominantly photo‐mechanically induced laser fragmentation mechanisms of organic microparticles (MP) are discussed.

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Critical Review on Nutritional, Bioactive, and Medicinal Potential of Spices and Herbs and Their Application in Food Fortification and Nanotechnology

Mandal

Sarkar

Chakraborty

2022

Appl Biochem Biotechnol

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Medicinal or herbal spices are grown in tropical moist evergreen forestland, surrounding most of the tropical and subtropical regions of Eastern Himalayas in India (Sikkim, Darjeeling regions), Bhutan, Nepal, Pakistan, Iran, Afghanistan, a few Central Asian countries, Middle East, USA, Europe, South East Asia, Japan, Malaysia, and Indonesia. According to the cultivation region surrounded, economic value, and vogue, these spices can be classified into major, minor, and colored tropical spices. In total, 24 tropical spices and herbs (cardamom, black jeera, fennel, poppy, coriander, fenugreek, bay leaves, clove, chili, cassia bark, black pepper, nutmeg, black mustard, turmeric, saffron, star anise, onion, dill, asafoetida, celery, allspice, kokum, greater galangal, and sweet flag) are described in this review. These spices show many pharmacological activities like anti-inflammatory, antimicrobial, anti-diabetic, anti-obesity, cardiovascular, gastrointestinal, central nervous system, and antioxidant activities. Numerous bioactive compounds are present in these selected spices, such as 1,8-cineole, monoterpene hydrocarbons, γ-terpinene, cuminaldehyde, trans-anethole, fenchone, estragole, benzylisoquinoline alkaloids, eugenol, cinnamaldehyde, piperine, linalool, malabaricone C, safrole, myristicin, elemicin, sinigrin, curcumin, bidemethoxycurcumin, dimethoxycurcumin, crocin, picrocrocin, quercetin, quercetin 4’-O-β-glucoside, apiol, carvone, limonene, α-phellandrene, galactomannan, rosmarinic acid, limonene, capsaicinoids, eugenol, garcinol, and α-asarone. Other than that, various spices are used to synthesize different types of metal-based and polymer-based nanoparticles like zinc oxide, gold, silver, selenium, silica, and chitosan nanoparticles which provide beneficial health effects such as antioxidant, anti-carcinogenic, anti-diabetic, enzyme retardation effect, and antimicrobial activity. The nanoparticles can also be used in environmental pollution management like dye decolorization and in chemical industries to enhance the rate of reaction by the use of catalytic activity of the nanoparticles. The nutritional value, phytochemical properties, health advantages, and both traditional and modern applications of these spices, along with their functions in food fortification, have been thoroughly discussed in this review

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Antibacterial activity of PLAL synthesized nanocinnamon

Cited by 42 publications

References 59 publications

Customised structural, optical and antibacterial characteristics of cinnamon nanoclusters produced inside organic solvent using 532 nm Q-switched Nd:YAG-pulse laser ablation

Customised structural, optical and antibacterial characteristics of cinnamon nanoclusters produced inside organic solvent using 532 nm Q-switched Nd:YAG-pulse laser ablation

Efficient Synthesis of Submicrometer‐Sized Active Pharmaceuticals by Laser Fragmentation in a Liquid‐Jet Passage Reactor with Minimum Degradation

Critical Review on Nutritional, Bioactive, and Medicinal Potential of Spices and Herbs and Their Application in Food Fortification and Nanotechnology

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