Antibacterial Activity of <i>Salvadora persica</i> L. (Miswak) Extracts against Multidrug Resistant Bacterial Clinical Isolates

Al-Ayed, Mohamed Saeed Zayed; Asaad, Ahmed Morad; Qureshi, Mohamed Ansar; Attia, Gouda H.; AlMarrani, Abduljabbar Hadi

doi:10.1155/2016/7083964

Cited by 46 publications

(32 citation statements)

References 21 publications

(29 reference statements)

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“…However, the role of the aqueous extract was largely as a reductant for the synthesis of NPs as the concentration used for the synthesis was too low to show its own antimicrobial activity (10–300 µg/mL). It has been demonstrated in an earlier study that the aqueous RE of S. persica L. exhibited considerable antimicrobial activity at concentrations range of 50–400 mg/mL [43]. In this study, antimicrobial activity of the RE was tested at a very low concentration (300 µg/mL, which is ~100 times lower), therefore, no antimicrobial activity was observed.…”

Section: Resultsmentioning

confidence: 82%

“Miswak” Based Green Synthesis of Silver Nanoparticles: Evaluation and Comparison of Their Microbicidal Activities with the Chemical Synthesis

et al. 2016

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Microbicidal potential of silver nanoparticles (Ag-NPs) can be drastically improved by improving their solubility or wettability in the aqueous medium. In the present study, we report the synthesis of both green and chemical synthesis of Ag-NPs, and evaluate the effect of the dispersion qualities of as-prepared Ag-NPs from both methods on their antimicrobial activities. The green synthesis of Ag-NPs is carried out by using an aqueous solution of readily available Salvadora persica L. root extract (RE) as a bioreductant. The formation of highly crystalline Ag-NPs was established by various analytical and microscopic techniques. The rich phenolic contents of S. persica L. RE (Miswak) not only promoted the reduction and formation of NPs but they also facilitated the stabilization of the Ag-NPs, which was established by Fourier transform infrared spectroscopy (FT-IR) analysis. Furthermore, the influence of the volume of the RE on the size and the dispersion qualities of the NPs was also evaluated. It was revealed that with increasing the volume of RE the size of the NPs was deteriorated, whereas at lower concentrations of RE smaller size and less aggregated NPs were obtained. During this study, the antimicrobial activities of both chemically and green synthesized Ag-NPs, along with the aqueous RE of S. persica L., were evaluated against various microorganisms. It was observed that the green synthesized Ag-NPs exhibit comparable or slightly higher antibacterial activities than the chemically obtained Ag-NPs.

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Section: Resultsmentioning

confidence: 82%

“Miswak” Based Green Synthesis of Silver Nanoparticles: Evaluation and Comparison of Their Microbicidal Activities with the Chemical Synthesis

et al. 2016

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“…baumannii may be attributed to the phytochemical components (trimethylamine, Salvadorin, chlorides, fluoride, silica, sulphur, vitamin C, tannins, saponins, flavonoids, sterols, beta-sitosterol, gallic acid, ellagic acid, ethyl gallate, galloyl glucose, chebulagic acid) of major active ingredients of Hiora-regular mouthwash such as Salvadora persica and Terminalia bellerica [24,25].…”

Section: Discussionmentioning

confidence: 99%

An Herbal Alternative to Control Nosocomial Pathogens in Aerosols and Splatter During Ultrasonic Scaling

Rajachandrasekaran¹,

Valiathan

Jayaraman

et al. 2019

Pesqui. bras. odontopediatria clín. integr.

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Objective: To evaluate the efficacy of herbal mouthwash (Himalaya Hiora Regular) against methicillin-resistant Staphylococcus aureus and Acinetobacter baumanni during ultrasonic scaling. Material and Methods: Group B (n=25) received herbal mouthwash and Group A (n=25) received 0.12% chlorhexidine mouthwash respectively as a preprocedural rinse. The aerosols produced by the ultrasonic unit were collected on MeReSa and Leeds Acinetobacter Agar plates. The experimental setting included eight different locations covering all areas of the operatory. The plates exposed to aerosols for a period of 30 minutes were incubated aerobically at 37 o C for 48hrs and the colony forming units (CFU) were statistically analyzed. Results: Herbal mouthwash (Himalaya Hiora Regular) showed a significant reduction in mean CFU of MRSA compared to 0.12% chlorhexidine. While herbal mouthwash was on par with 0.12% chlorhexidine in the reduction of A. baumannii. Conclusion: Herbal mouthwash was found to be more effective against MRSA than 0.12% Chlorhexidine mouthwash as a pre-procedural rinse. Both herbal mouthwash and chlorhexidine mouthwash was found to be effective against A. baumannii. Herbal mouthwash may be a safe alternative to chlorhexidine against nosocomial pathogens like MRSA and A. baumannii.

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“…Medicinal plants have been used for medicinal purposes worldwide, because of their significant health benefits. Various plant extract has great potential against infectious agents and can be used for therapeutic purposes (8) . The use of plant products, either as pure compounds or as standardized plant extracts, could be of great significance in the treatment of microbial diseases (9) .…”

Section: Introductionmentioning

confidence: 99%

Biofilm inhibition of UTI pathogens using Terminalia arjuna and Ipomea carnea plant extract

Khalate¹,

Chandgude²,

Kambale³

et al. 2020

IJST

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Objectives: To evaluate the antibiofilm potential of Terminalia arjuna and Ipomea carnea plant extract against potent biofilm forming UTI pathogens. Methods/Statistical analysis:In this study, previously isolated and characterized three UTI pathogens viz. Escherichia coli, Pseudomonas aeruginosa and Staphylococcus equorum were used to evaluate antibiofilm potential of selected plants. Soxhlet apparatus was used with a solvent methanol for the extraction process. For the evaluation of antibiofilm activity of different concentrations (2, 4, 6, 8 and 10 mg/ml) of plant extract in 3% DMSO Crystal violet assay was used. Findings:The methanolic bark extract of T. arjuna showed maximum activity up to 89.84% at 10mg/ml. against S. equorum while leaves extract of I. carnea gives maximum antibiofilm activity up to 67.53% at 2mg/ml against E. coli. Applications: The result shows that the investigated plants might be helpful in the development of potent herbal drugs to treat UTI. https://www.indjst.org/ 2452 Urinary tract infections (UTIs) are the most common human infectious disease affecting the bladder, kidneys and urinary tracts. Escherichia coli is the most frequent pathogen causing UTI in humans and one of the most common causes of Gram-negative bacteremia in hospitalized patients Soxhlet extraction; Crystal violet assay

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Antibacterial Activity of Salvadora persica L. (Miswak) Extracts against Multidrug Resistant Bacterial Clinical Isolates

Cited by 46 publications

References 21 publications

“Miswak” Based Green Synthesis of Silver Nanoparticles: Evaluation and Comparison of Their Microbicidal Activities with the Chemical Synthesis

“Miswak” Based Green Synthesis of Silver Nanoparticles: Evaluation and Comparison of Their Microbicidal Activities with the Chemical Synthesis

An Herbal Alternative to Control Nosocomial Pathogens in Aerosols and Splatter During Ultrasonic Scaling

Biofilm inhibition of UTI pathogens using Terminalia arjuna and Ipomea carnea plant extract

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